{
  "url": "https://dantelabs.com/hu/genes/rnf43",
  "gene": {
    "slug": "rnf43",
    "symbol": "RNF43",
    "name": "ring finger protein 43",
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    "location": "17q22",
    "locusType": "gene with protein product",
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      "DKFZp781H0392",
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    "uniprot": [
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      "chrom": "17",
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      "ensemblTranscript": "ENST00000407977.7",
      "refseqTranscript": "NM_017763.6",
      "ensemblProtein": "ENSP00000385328.2",
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    },
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      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
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    },
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        {
          "symbol": "CUEDC1",
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        {
          "symbol": "VEZF1",
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        {
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          "ensemblId": "ENSG00000266086",
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        {
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        {
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        {
          "symbol": "HSF5",
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        {
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        {
          "symbol": "SEPTIN4",
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        {
          "symbol": "TEX14",
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        {
          "symbol": "RAD51C",
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        {
          "symbol": "PPM1E",
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          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "ppm1e"
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      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "adenomatous-colonic-polyposis",
        "name": "Adenomatous colonic polyposis",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/adenomatous-colonic-polyposis"
      },
      {
        "slug": "biliary-tract-neoplasm",
        "name": "Biliary tract neoplasm",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/biliary-tract-neoplasm"
      },
      {
        "slug": "bladder-carcinoma",
        "name": "Bladder carcinoma",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/bladder-carcinoma"
      },
      {
        "slug": "breast-carcinoma",
        "name": "Breast cancer",
        "systems": [
          "abnormality-of-the-breast",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/breast-carcinoma"
      },
      {
        "slug": "melanoma",
        "name": "Cancer of skin pigment cells",
        "systems": [
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/melanoma"
      },
      {
        "slug": "colorectal-polyposis",
        "name": "Colorectal polyposis",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/colorectal-polyposis"
      },
      {
        "slug": "gastric-diverticulum",
        "name": "Gastric diverticulum",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/gastric-diverticulum"
      },
      {
        "slug": "germ-cell-neoplasia",
        "name": "Germ cell neoplasia",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/germ-cell-neoplasia"
      },
      {
        "slug": "hodgkin-lymphoma",
        "name": "Hodgkin lymphoma",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/hodgkin-lymphoma"
      },
      {
        "slug": "neoplasm-of-the-large-intestine",
        "name": "Large intestine tumor",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/neoplasm-of-the-large-intestine"
      },
      {
        "slug": "ovarian-neoplasm",
        "name": "Ovarian cancer",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/ovarian-neoplasm"
      },
      {
        "slug": "pancreatic-adenocarcinoma",
        "name": "Pancreatic adenocarcinoma",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/pancreatic-adenocarcinoma"
      },
      {
        "slug": "prostate-cancer",
        "name": "Prostate cancer",
        "systems": [
          "abnormality-of-the-genitourinary-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/prostate-cancer"
      },
      {
        "slug": "schwannoma",
        "name": "Schwannoma",
        "systems": [
          "abnormality-of-the-nervous-system",
          "neoplasm"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/schwannoma"
      },
      {
        "slug": "serrated-intestinal-polyps",
        "name": "Serrated intestinal polyps",
        "systems": [
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "url": "https://dantelabs.com/traits/serrated-intestinal-polyps"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}