{
  "url": "https://dantelabs.com/hu/genes/popdc2",
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        "name": "Progressive Cardiac Conduction Disease & Sick Sinus Syndrome",
        "diseases": [
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            "name": "Cardiac Conduction Defect",
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            "inheritance": null,
            "description": "A general term for disorders of electrical conduction in the heart, including inherited forms of atrioventricular block.",
            "management": null,
            "evidence": {
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        ],
        "url": "https://dantelabs.com/hu/conditions/cardiac-conduction-disease-sick-sinus-syndrome"
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    ],
    "pharmacogenomics": [],
    "traits": [],
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        "name": "2:1 atrioventricular block",
        "systems": [
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/2-1-atrioventricular-block"
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        "slug": "atrial-flutter",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/atrial-flutter"
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      {
        "slug": "chest-pain",
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        "systems": [
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/chest-pain"
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      {
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        "name": "Enlarged and thickened heart muscle",
        "systems": [
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypertrophic-cardiomyopathy"
      },
      {
        "slug": "premature-ventricular-contraction",
        "name": "Extra heart beat",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/premature-ventricular-contraction"
      },
      {
        "slug": "fatty-replacement-of-ventricular-myocardial-tissue",
        "name": "Fatty replacement of ventricular myocardial tissue",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fatty-replacement-of-ventricular-myocardial-tissue"
      },
      {
        "slug": "first-degree-atrioventricular-block",
        "name": "First degree atrioventricular block",
        "systems": [
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        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/first-degree-atrioventricular-block"
      },
      {
        "slug": "cardiac-arrest",
        "name": "Heart stops beating",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/cardiac-arrest"
      },
      {
        "slug": "myocarditis",
        "name": "Inflammation of heart muscle",
        "systems": [
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/myocarditis"
      },
      {
        "slug": "left-ventricular-systolic-dysfunction",
        "name": "Left ventricular systolic dysfunction",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/left-ventricular-systolic-dysfunction"
      },
      {
        "slug": "mobitz-i-atrioventricular-block",
        "name": "Mobitz I atrioventricular block",
        "systems": [
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        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/mobitz-i-atrioventricular-block"
      },
      {
        "slug": "monomorphic-ventricular-tachycardia",
        "name": "Monomorphic ventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/monomorphic-ventricular-tachycardia"
      },
      {
        "slug": "myocardial-fibrosis",
        "name": "Myocardial fibrosis",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/myocardial-fibrosis"
      },
      {
        "slug": "palpitations",
        "name": "Palpitations",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/palpitations"
      },
      {
        "slug": "atrial-fibrillation",
        "name": "Quivering upper heart chambers resulting in irregular heartbeat",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/atrial-fibrillation"
      },
      {
        "slug": "second-degree-atrioventricular-block",
        "name": "Second degree atrioventricular block",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/second-degree-atrioventricular-block"
      },
      {
        "slug": "sinoatrial-block",
        "name": "Sinoatrial block",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/sinoatrial-block"
      },
      {
        "slug": "sinus-bradycardia",
        "name": "Sinus bradycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/sinus-bradycardia"
      },
      {
        "slug": "ventricular-septal-hypertrophy",
        "name": "Ventricular septal hypertrophy",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/ventricular-septal-hypertrophy"
      },
      {
        "slug": "ventricular-tachycardia",
        "name": "Ventricular tachycardia",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/ventricular-tachycardia"
      }
    ],
    "related": [
      {
        "slug": "des",
        "symbol": "DES",
        "name": "desmin",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/des"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "name": "lamin A/C",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/lmna"
      }
    ],
    "sources": {
      "bundleId": "2026.10.18-8b139e39",
      "panel": "2026-10-18",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}