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"ENSG00000143226", "biotype": "protein_coding", "start": 161505415, "end": 161524013, "strand": "+", "slug": "fcgr2a" }, { "symbol": "HSPA6", "ensemblId": "ENSG00000173110", "biotype": "protein_coding", "start": 161524540, "end": 161526894, "strand": "+", "slug": "hspa6" }, { "symbol": "FCGR3A", "ensemblId": "ENSG00000203747", "biotype": "protein_coding", "start": 161541738, "end": 161550968, "strand": "-", "slug": "fcgr3a" }, { "symbol": "", "ensemblId": "ENSG00000289768", "biotype": "protein_coding", "start": 161544807, "end": 161631456, "strand": "-" } ], "truncated": false }, "reports": [ { "slug": "ectodermal-dysplasias", "name": "Ectodermal Dysplasias", "diseases": [ { "mondoId": "MONDO:0024565", "name": "Ectodermal dysplasia-syndactyly syndrome 1", "genes": 1, "inheritance": "autosomal-recessive", "description": "A NECTIN4 disorder with sparse hair, tooth anomalies and fused fingers or toes.", "management": null, "evidence": { "gencc": [ "G2P", "PanelApp Australia" ], "acmgSf": false, "inheritance": [ "autosomal-recessive" ] }, "sameAsReport": false, "broad": false } ], "url": "https://dantelabs.com/hu/conditions/ectodermal-dysplasias" } ], "pharmacogenomics": [], "traits": [], "phenotypes": [ { "slug": "absent-facial-hair", "name": "Absent facial hair", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/absent-facial-hair" }, { "slug": "coarse-hair", "name": "Coarse hair", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/coarse-hair" }, { "slug": "conical-tooth", "name": "Cone shaped tooth", "systems": [ "abnormality-of-head-or-neck" ], "url": "https://dantelabs.com/traits/conical-tooth" }, { "slug": "ectodermal-dysplasia", "name": "Ectodermal dysplasia", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/ectodermal-dysplasia" }, { "slug": "pili-torti", "name": "Flattened and twisted hair", "systems": [ "abnormality-of-the-integument" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/pili-torti" }, { "slug": "alopecia", "name": "Hair loss", "systems": [ "abnormality-of-the-integument" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/alopecia" }, { "slug": "heat-intolerance", "name": "Heat intolerance", "systems": [ "abnormality-of-metabolism-homeostasis" ], "frequency": "occasional", "url": "https://dantelabs.com/traits/heat-intolerance" }, { "slug": "palmar-hyperkeratosis", "name": "Palmar hyperkeratosis", "systems": [ "abnormality-of-limbs", "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/palmar-hyperkeratosis" }, { "slug": "patchy-alopecia", "name": "Patchy baldness", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/patchy-alopecia" }, { "slug": "small-nail", "name": "Small nail", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/small-nail" }, { "slug": "sparse-eyelashes", "name": "Sparse eyelashes", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/sparse-eyelashes" }, { "slug": "sparse-scalp-hair", "name": "Sparse scalp hair", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/sparse-scalp-hair" }, { "slug": "enamel-hypoplasia", "name": "Thin dental enamel", "systems": [ "abnormality-of-head-or-neck", "abnormality-of-the-musculoskeletal-system" ], "url": "https://dantelabs.com/traits/enamel-hypoplasia" }, { "slug": "hypoplastic-toenails", "name": "Underdeveloped toenails", "systems": [ "abnormality-of-the-integument" ], "url": "https://dantelabs.com/traits/hypoplastic-toenails" }, { "slug": "4-5-toe-syndactyly", "name": "Webbed 4th-5th toes", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/4-5-toe-syndactyly" }, { "slug": "cutaneous-finger-syndactyly", "name": "Webbed fingers", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "url": "https://dantelabs.com/traits/cutaneous-finger-syndactyly" }, { "slug": "2-4-finger-cutaneous-syndactyly", "name": "Webbed index through ring fingers", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "frequent", "url": "https://dantelabs.com/traits/2-4-finger-cutaneous-syndactyly" }, { "slug": "2-3-toe-cutaneous-syndactyly", "name": "Webbed skin of 2nd-3rd toes", "systems": [ "abnormality-of-limbs", "abnormality-of-the-musculoskeletal-system" ], "frequency": "obligate", "url": "https://dantelabs.com/traits/2-3-toe-cutaneous-syndactyly" }, { "slug": "widely-spaced-teeth", "name": "Widely spaced teeth", "systems": [ "abnormality-of-head-or-neck" ], "url": "https://dantelabs.com/traits/widely-spaced-teeth" } ], "related": [], "sources": { "bundleId": "2026.10.17-8666dff2", "panel": "2026-10-17", "acmgSf": "SF v3.2" }, "locusKind": "proteinCoding" }, "variants": { "total": 0, "url": null, "items": [] } }