{
  "url": "https://dantelabs.com/hu/genes/meox1",
  "gene": {
    "slug": "meox1",
    "symbol": "MEOX1",
    "name": "mesenchyme homeobox 1",
    "hgnc": "HGNC:7013",
    "summary": null,
    "location": "17q21.31",
    "locusType": "gene with protein product",
    "aliases": [
      "MOX1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000005102",
    "entrezId": 4222,
    "omim": [
      "600147"
    ],
    "uniprot": [
      "P50221"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "17",
      "start": 43640389,
      "end": 43661922,
      "strand": "-",
      "ensemblTranscript": "ENST00000318579.9",
      "refseqTranscript": "NM_004527.4",
      "ensemblProtein": "ENSP00000321684.4",
      "refseqProtein": "NP_004518.1",
      "exons": [
        {
          "start": 43640389,
          "end": 43642032
        },
        {
          "start": 43643488,
          "end": 43643660
        },
        {
          "start": 43661066,
          "end": 43661922
        }
      ],
      "cds": {
        "start": 43641910,
        "end": 43661534
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
      "start": 41717756,
      "end": 41739322,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 43151156,
      "end": 44151155,
      "genes": [
        {
          "symbol": "BRCA1",
          "ensemblId": "ENSG00000012048",
          "biotype": "protein_coding",
          "start": 43044292,
          "end": 43170245,
          "strand": "-",
          "slug": "brca1"
        },
        {
          "symbol": "NBR1",
          "ensemblId": "ENSG00000188554",
          "biotype": "protein_coding",
          "start": 43170317,
          "end": 43211690,
          "strand": "+",
          "slug": "nbr1"
        },
        {
          "symbol": "TMEM106A",
          "ensemblId": "ENSG00000184988",
          "biotype": "protein_coding",
          "start": 43211835,
          "end": 43220041,
          "strand": "+",
          "slug": "tmem106a"
        },
        {
          "symbol": "CCDC200",
          "ensemblId": "ENSG00000236383",
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          "slug": "ccdc200"
        },
        {
          "symbol": "ARL4D",
          "ensemblId": "ENSG00000175906",
          "biotype": "protein_coding",
          "start": 43398150,
          "end": 43408660,
          "strand": "+",
          "slug": "arl4d"
        },
        {
          "symbol": "DHX8",
          "ensemblId": "ENSG00000067596",
          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "dhx8"
        },
        {
          "symbol": "ETV4",
          "ensemblId": "ENSG00000175832",
          "biotype": "protein_coding",
          "start": 43527841,
          "end": 43579620,
          "strand": "-",
          "slug": "etv4"
        },
        {
          "symbol": "SOST",
          "ensemblId": "ENSG00000167941",
          "biotype": "protein_coding",
          "start": 43753738,
          "end": 43758791,
          "strand": "-",
          "slug": "sost"
        },
        {
          "symbol": "DUSP3",
          "ensemblId": "ENSG00000108861",
          "biotype": "protein_coding",
          "start": 43763629,
          "end": 43779000,
          "strand": "-",
          "slug": "dusp3"
        },
        {
          "symbol": "CFAP97D1",
          "ensemblId": "ENSG00000231256",
          "biotype": "protein_coding",
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          "end": 43787620,
          "strand": "+",
          "slug": "cfap97d1"
        },
        {
          "symbol": "MPP3",
          "ensemblId": "ENSG00000161647",
          "biotype": "protein_coding",
          "start": 43800795,
          "end": 43833203,
          "strand": "-",
          "slug": "mpp3"
        },
        {
          "symbol": "CD300LG",
          "ensemblId": "ENSG00000161649",
          "biotype": "protein_coding",
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          "end": 43863639,
          "strand": "+",
          "slug": "cd300lg"
        },
        {
          "symbol": "MPP2",
          "ensemblId": "ENSG00000108852",
          "biotype": "protein_coding",
          "start": 43875352,
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          "strand": "-",
          "slug": "mpp2"
        },
        {
          "symbol": "PPY",
          "ensemblId": "ENSG00000108849",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "ppy"
        },
        {
          "symbol": "PYY",
          "ensemblId": "ENSG00000131096",
          "biotype": "protein_coding",
          "start": 43952733,
          "end": 44004469,
          "strand": "-",
          "slug": "pyy"
        },
        {
          "symbol": "NAGS",
          "ensemblId": "ENSG00000161653",
          "biotype": "protein_coding",
          "start": 44004581,
          "end": 44011213,
          "strand": "+",
          "slug": "nags"
        },
        {
          "symbol": "TMEM101",
          "ensemblId": "ENSG00000091947",
          "biotype": "protein_coding",
          "start": 44008986,
          "end": 44023946,
          "strand": "-",
          "slug": "tmem101"
        },
        {
          "symbol": "LSM12",
          "ensemblId": "ENSG00000161654",
          "biotype": "protein_coding",
          "start": 44033931,
          "end": 44067619,
          "strand": "-",
          "slug": "lsm12"
        },
        {
          "symbol": "G6PC3",
          "ensemblId": "ENSG00000141349",
          "biotype": "protein_coding",
          "start": 44070620,
          "end": 44094678,
          "strand": "+",
          "slug": "g6pc3"
        },
        {
          "symbol": "HDAC5",
          "ensemblId": "ENSG00000108840",
          "biotype": "protein_coding",
          "start": 44076746,
          "end": 44123702,
          "strand": "-",
          "slug": "hdac5"
        },
        {
          "symbol": "HROB",
          "ensemblId": "ENSG00000125319",
          "biotype": "protein_coding",
          "start": 44141903,
          "end": 44162481,
          "strand": "+",
          "slug": "hrob"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "ectopic-anus",
        "name": "Abnormal anus position",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ectopic-anus"
      },
      {
        "slug": "abnormal-cardiovascular-system-morphology",
        "name": "Abnormal cardiovascular system morphology",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-cardiovascular-system-morphology"
      },
      {
        "slug": "abnormal-cranial-nerve-morphology",
        "name": "Abnormal cranial nerve morphology",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-cranial-nerve-morphology"
      },
      {
        "slug": "ectopic-kidney",
        "name": "Abnormal kidney location",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ectopic-kidney"
      },
      {
        "slug": "abnormal-sacrum-morphology",
        "name": "Abnormal sacrum morphology",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-sacrum-morphology"
      },
      {
        "slug": "abnormal-vertebral-segmentation-and-fusion",
        "name": "Abnormal vertebral segmentation and fusion",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-vertebral-segmentation-and-fusion"
      },
      {
        "slug": "abnormality-of-the-genitourinary-system",
        "name": "Abnormality of the genitourinary system",
        "systems": [],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-the-genitourinary-system"
      },
      {
        "slug": "abnormal-rib-morphology",
        "name": "Abnormality of the ribs",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-rib-morphology"
      },
      {
        "slug": "abnormal-shoulder-morphology",
        "name": "Abnormality of the shoulder",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-shoulder-morphology"
      },
      {
        "slug": "abnormality-of-the-vertebral-column",
        "name": "Abnormality of the vertebral column",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormality-of-the-vertebral-column"
      },
      {
        "slug": "abnormal-pinna-morphology",
        "name": "Abnormally shaped ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "url": "https://dantelabs.com/traits/abnormal-pinna-morphology"
      },
      {
        "slug": "anal-atresia",
        "name": "Absent anus",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/anal-atresia"
      },
      {
        "slug": "renal-hypoplasia-aplasia",
        "name": "Absent/small kidney",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/renal-hypoplasia-aplasia"
      },
      {
        "slug": "cervical-c2-c3-vertebral-fusion",
        "name": "Cervical C2/C3 vertebral fusion",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/cervical-c2-c3-vertebral-fusion"
      },
      {
        "slug": "cleft-palate",
        "name": "Cleft palate",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/cleft-palate"
      },
      {
        "slug": "cleft-upper-lip",
        "name": "Cleft upper lip",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/cleft-upper-lip"
      },
      {
        "slug": "cognitive-impairment",
        "name": "Cognitive impairment",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/cognitive-impairment"
      },
      {
        "slug": "conductive-hearing-impairment",
        "name": "Conductive deafness",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "url": "https://dantelabs.com/traits/conductive-hearing-impairment"
      },
      {
        "slug": "congenital-muscular-torticollis",
        "name": "Congenital muscular torticollis",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/congenital-muscular-torticollis"
      },
      {
        "slug": "facial-asymmetry",
        "name": "Facial asymmetry",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/facial-asymmetry"
      },
      {
        "slug": "fused-cervical-vertebrae",
        "name": "Fused neck",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "url": "https://dantelabs.com/traits/fused-cervical-vertebrae"
      },
      {
        "slug": "headache",
        "name": "Headache",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/headache"
      },
      {
        "slug": "hearing-impairment",
        "name": "Hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hearing-impairment"
      },
      {
        "slug": "sprengel-anomaly",
        "name": "High shoulder blade",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/sprengel-anomaly"
      },
      {
        "slug": "ventricular-septal-defect",
        "name": "Hole in heart wall separating two lower heart chambers",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ventricular-septal-defect"
      },
      {
        "slug": "limitation-of-neck-motion",
        "name": "Limitation of neck motion",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/limitation-of-neck-motion"
      },
      {
        "slug": "limited-neck-range-of-motion",
        "name": "Limited neck range of motion",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "url": "https://dantelabs.com/traits/limited-neck-range-of-motion"
      },
      {
        "slug": "low-posterior-hairline",
        "name": "Low hairline at back of neck",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/low-posterior-hairline"
      },
      {
        "slug": "spinal-canal-stenosis",
        "name": "Narrow spinal canal",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/spinal-canal-stenosis"
      },
      {
        "slug": "neck-pain",
        "name": "Neck pain",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/neck-pain"
      },
      {
        "slug": "hemiplegia-hemiparesis",
        "name": "Paralysis or weakness of one side of body",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hemiplegia-hemiparesis"
      },
      {
        "slug": "scoliosis",
        "name": "Scoliosis",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/scoliosis"
      },
      {
        "slug": "sensorineural-hearing-impairment",
        "name": "Sensorineural hearing impairment",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "url": "https://dantelabs.com/traits/sensorineural-hearing-impairment"
      },
      {
        "slug": "short-neck",
        "name": "Short neck",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/short-neck"
      },
      {
        "slug": "spina-bifida-occulta",
        "name": "Spina bifida occulta",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/spina-bifida-occulta"
      },
      {
        "slug": "spina-bifida",
        "name": "Split spine",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/spina-bifida"
      },
      {
        "slug": "synkinesis",
        "name": "Synkinesis",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/synkinesis"
      },
      {
        "slug": "webbed-neck",
        "name": "Webbed neck",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/webbed-neck"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}