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        "url": "https://dantelabs.com/traits/bulbous-nose"
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      {
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        "systems": [
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/cerebral-visual-impairment"
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/everted-lower-lip-vermilion"
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        "slug": "epileptic-encephalopathy",
        "name": "Epileptic encephalopathy",
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/epileptic-encephalopathy"
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      {
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        "name": "Focal impaired awareness seizure",
        "systems": [
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/focal-impaired-awareness-seizure"
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        "slug": "thick-vermilion-border",
        "name": "Full lips",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/thick-vermilion-border"
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/periorbital-fullness"
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      {
        "slug": "generalized-tonic-seizure",
        "name": "Generalized tonic seizure",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/generalized-tonic-seizure"
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        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "bilateral-tonic-clonic-seizure",
        "name": "Grand mal seizures",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/bilateral-tonic-clonic-seizure"
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      {
        "slug": "hypoplasia-of-the-pons",
        "name": "Hypoplasia of the pons",
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        "url": "https://dantelabs.com/traits/hypoplasia-of-the-pons"
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        "url": "https://dantelabs.com/traits/hypsarrhythmia"
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        "name": "Inability to walk",
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        "url": "https://dantelabs.com/traits/inability-to-walk"
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      {
        "slug": "infantile-spasms",
        "name": "Infantile spasms",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/infantile-spasms"
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      {
        "slug": "intellectual-disability",
        "name": "Intellectual disability",
        "systems": [
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/intellectual-disability"
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      {
        "slug": "myoclonus",
        "name": "Jerking",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/myoclonus"
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      {
        "slug": "large-earlobe",
        "name": "Large earlobe",
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/large-earlobe"
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      {
        "slug": "long-eyelashes",
        "name": "Long eyelashes",
        "systems": [
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          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/long-eyelashes"
      },
      {
        "slug": "low-anterior-hairline",
        "name": "Low frontal hairline",
        "systems": [
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          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/low-anterior-hairline"
      },
      {
        "slug": "hypotonia",
        "name": "Low muscle tone",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypotonia"
      },
      {
        "slug": "synophrys",
        "name": "Monobrow",
        "systems": [
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          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/synophrys"
      },
      {
        "slug": "multifocal-epileptiform-discharges",
        "name": "Multifocal epileptiform discharges",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/multifocal-epileptiform-discharges"
      },
      {
        "slug": "narrow-forehead",
        "name": "Narrow forehead",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/narrow-forehead"
      },
      {
        "slug": "anteverted-nares",
        "name": "Nasal tip, upturned",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/anteverted-nares"
      },
      {
        "slug": "occipital-cortical-atrophy",
        "name": "Occipital cortical atrophy",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/occipital-cortical-atrophy"
      },
      {
        "slug": "reduced-eye-contact",
        "name": "Poor eye contact",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/reduced-eye-contact"
      },
      {
        "slug": "poor-speech",
        "name": "Poor speech",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/poor-speech"
      },
      {
        "slug": "prominent-ear-helix",
        "name": "Prominent ear helix",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/prominent-ear-helix"
      },
      {
        "slug": "prominent-nasal-bridge",
        "name": "Prominent nasal bridge",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/prominent-nasal-bridge"
      },
      {
        "slug": "motor-stereotypy",
        "name": "Repetitive movements",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/motor-stereotypy"
      },
      {
        "slug": "short-philtrum",
        "name": "Short philtrum",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/short-philtrum"
      },
      {
        "slug": "atonic-seizure",
        "name": "Sudden loss of muscle tone",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/atonic-seizure"
      },
      {
        "slug": "supravalvular-aortic-stenosis",
        "name": "Supravalvular aortic stenosis",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/supravalvular-aortic-stenosis"
      },
      {
        "slug": "thick-eyebrow",
        "name": "Thick eyebrow",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/thick-eyebrow"
      },
      {
        "slug": "tonic-seizure",
        "name": "Tonic seizure",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/tonic-seizure"
      },
      {
        "slug": "hypoplasia-of-the-corpus-callosum",
        "name": "Underdevelopment of part of brain called corpus callosum",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypoplasia-of-the-corpus-callosum"
      }
    ],
    "related": [
      {
        "slug": "aars1",
        "symbol": "AARS1",
        "name": "alanyl-tRNA synthetase 1",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/aars1"
      },
      {
        "slug": "abat",
        "symbol": "ABAT",
        "name": "4-aminobutyrate aminotransferase",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/abat"
      },
      {
        "slug": "actl6b",
        "symbol": "ACTL6B",
        "name": "actin like 6B",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/actl6b"
      },
      {
        "slug": "adam22",
        "symbol": "ADAM22",
        "name": "ADAM metallopeptidase domain 22",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/adam22"
      },
      {
        "slug": "aldh7a1",
        "symbol": "ALDH7A1",
        "name": "aldehyde dehydrogenase 7 family member A1",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/aldh7a1"
      },
      {
        "slug": "alg13",
        "symbol": "ALG13",
        "name": "ALG13 UDP-N-acetylglucosaminyltransferase subunit",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/alg13"
      },
      {
        "slug": "ap3b2",
        "symbol": "AP3B2",
        "name": "adaptor related protein complex 3 subunit beta 2",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/ap3b2"
      },
      {
        "slug": "arhgef9",
        "symbol": "ARHGEF9",
        "name": "Cdc42 guanine nucleotide exchange factor 9",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/arhgef9"
      },
      {
        "slug": "arv1",
        "symbol": "ARV1",
        "name": "ARV1 fatty acid homeostasis modulator",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/arv1"
      },
      {
        "slug": "arx",
        "symbol": "ARX",
        "name": "aristaless related homeobox",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/arx"
      },
      {
        "slug": "atp1a2",
        "symbol": "ATP1A2",
        "name": "ATPase Na+/K+ transporting subunit alpha 2",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/atp1a2"
      },
      {
        "slug": "atp1a3",
        "symbol": "ATP1A3",
        "name": "ATPase Na+/K+ transporting subunit alpha 3",
        "shared": 1,
        "url": "https://dantelabs.com/hu/genes/atp1a3"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}