{
  "url": "https://dantelabs.com/hu/genes/bcl2",
  "gene": {
    "slug": "bcl2",
    "symbol": "BCL2",
    "name": "BCL2 apoptosis regulator",
    "hgnc": "HGNC:990",
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    "location": "18q21.33",
    "locusType": "gene with protein product",
    "aliases": [
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    "previousSymbols": [],
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    "uniprot": [
      "P10415"
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    "model": {
      "build": "GRCh38",
      "release": "v1.5",
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      "start": 63123346,
      "end": 63319769,
      "strand": "-",
      "ensemblTranscript": "ENST00000333681.5",
      "refseqTranscript": "NM_000633.3",
      "ensemblProtein": "ENSP00000329623.3",
      "refseqProtein": "NP_000624.2",
      "exons": [
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        },
        {
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      "cds": {
        "start": 63128625,
        "end": 63318666
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    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "18",
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      "end": 60987361,
      "strand": "-"
    },
    "neighbourhood": {
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      "genes": [
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          "ensemblId": "ENSG00000081913",
          "biotype": "protein_coding",
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          "end": 62980433,
          "strand": "+",
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        },
        {
          "symbol": "KDSR",
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          "biotype": "protein_coding",
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          "end": 63367615,
          "strand": "-",
          "slug": "kdsr"
        },
        {
          "symbol": "VPS4B",
          "ensemblId": "ENSG00000119541",
          "biotype": "protein_coding",
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          "end": 63422521,
          "strand": "-",
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        },
        {
          "symbol": "SERPINB5",
          "ensemblId": "ENSG00000206075",
          "biotype": "protein_coding",
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          "end": 63505085,
          "strand": "+",
          "slug": "serpinb5"
        },
        {
          "symbol": "SERPINB12",
          "ensemblId": "ENSG00000166634",
          "biotype": "protein_coding",
          "start": 63542369,
          "end": 63569329,
          "strand": "+",
          "slug": "serpinb12"
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        {
          "symbol": "SERPINB13",
          "ensemblId": "ENSG00000197641",
          "biotype": "protein_coding",
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          "strand": "+",
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        {
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          "strand": "-",
          "slug": "serpinb4"
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        {
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          "biotype": "protein_coding",
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          "end": 63726432,
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          "slug": "serpinb11"
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        {
          "symbol": "SERPINB3",
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          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "serpinb3"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-peritoneum-morphology",
        "name": "Abnormal peritoneum morphology",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-peritoneum-morphology"
      },
      {
        "slug": "ascites",
        "name": "Accumulation of fluid in the abdomen",
        "systems": [
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ascites"
      },
      {
        "slug": "lymphoma",
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        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/lymphoma"
      },
      {
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        "name": "Fatigue",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fatigue"
      },
      {
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        "name": "Fever",
        "systems": [
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        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/fever"
      },
      {
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        "name": "Fluid around lungs",
        "systems": [
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          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pleural-effusion"
      },
      {
        "slug": "hypercalcemia",
        "name": "High blood calcium levels",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypercalcemia"
      },
      {
        "slug": "increased-circulating-lactate-dehydrogenase-concentration",
        "name": "Increased circulating lactate dehydrogenase concentration",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/increased-circulating-lactate-dehydrogenase-concentration"
      },
      {
        "slug": "splenomegaly",
        "name": "Increased spleen size",
        "systems": [
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          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/splenomegaly"
      },
      {
        "slug": "mediastinal-mass",
        "name": "Mediastinal mass",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/mediastinal-mass"
      },
      {
        "slug": "meningitis",
        "name": "Meningitis",
        "systems": [
          "abnormality-of-the-immune-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/meningitis"
      },
      {
        "slug": "night-sweats",
        "name": "Night sweats",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/night-sweats"
      },
      {
        "slug": "skin-nodule",
        "name": "Skin nodule",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/skin-nodule"
      },
      {
        "slug": "lymphedema",
        "name": "Swelling caused by excess lymph fluid under skin",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/lymphedema"
      },
      {
        "slug": "lymphadenopathy",
        "name": "Swollen lymph nodes",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/lymphadenopathy"
      },
      {
        "slug": "mediastinal-lymphadenopathy",
        "name": "Swollen lymph nodes in center of chest",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-immune-system",
          "abnormality-of-the-thoracic-cavity"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/mediastinal-lymphadenopathy"
      },
      {
        "slug": "weight-loss",
        "name": "Weight loss",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/weight-loss"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}