{
  "url": "https://dantelabs.com/genes/myc",
  "gene": {
    "slug": "myc",
    "symbol": "MYC",
    "name": "MYC proto-oncogene, bHLH transcription factor",
    "hgnc": "HGNC:7553",
    "summary": null,
    "location": "8q24.21",
    "locusType": "gene with protein product",
    "aliases": [
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      "bHLHe39",
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    "previousSymbols": [],
    "ensemblId": "ENSG00000136997",
    "entrezId": 4609,
    "omim": [
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    "uniprot": [
      "P01106"
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    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "8",
      "start": 127736231,
      "end": 127742951,
      "strand": "+",
      "ensemblTranscript": "ENST00000621592.8",
      "refseqTranscript": "NM_002467.6",
      "ensemblProtein": "ENSP00000478887.2",
      "refseqProtein": "NP_002458.2",
      "exons": [
        {
          "start": 127736231,
          "end": 127736623
        },
        {
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          "end": 127739019
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        {
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        }
      ],
      "cds": {
        "start": 127736594,
        "end": 127740958
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    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "8",
      "start": 128747680,
      "end": 128753674,
      "strand": "+"
    },
    "neighbourhood": {
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      "start": 127239591,
      "end": 128239590,
      "genes": [
        {
          "symbol": "POU5F1B",
          "ensemblId": "ENSG00000212993",
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          "end": 127420066,
          "strand": "+",
          "slug": "pou5f1b"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abdominal-pain",
        "name": "Abdominal pain",
        "systems": [
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          "constitutional-symptom"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abdominal-pain"
      },
      {
        "slug": "abnormal-lymph-node-morphology",
        "name": "Abnormal lymph node histology",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-lymph-node-morphology"
      },
      {
        "slug": "abnormality-of-the-liver",
        "name": "Abnormality of the liver",
        "systems": [
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-liver"
      },
      {
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        "name": "Abnormality of the ovary",
        "systems": [
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        "url": "https://dantelabs.com/traits/abnormality-of-the-ovary"
      },
      {
        "slug": "abnormality-of-the-pancreas",
        "name": "Abnormality of the pancreas",
        "systems": [
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        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-pancreas"
      },
      {
        "slug": "abnormality-of-the-spleen",
        "name": "Abnormality of the spleen",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormality-of-the-spleen"
      },
      {
        "slug": "abnormal-bone-marrow-cell-morphology",
        "name": "Bone marrow disease",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-bone-marrow-cell-morphology"
      },
      {
        "slug": "burkitt-lymphoma",
        "name": "Burkitt lymphoma",
        "systems": [
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          "neoplasm"
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        "url": "https://dantelabs.com/traits/burkitt-lymphoma"
      },
      {
        "slug": "immunodeficiency",
        "name": "Decreased immune function",
        "systems": [
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        "url": "https://dantelabs.com/traits/immunodeficiency"
      },
      {
        "slug": "decreased-total-cd4-t-cell-proportion",
        "name": "Decreased total CD4+ T cell proportion",
        "systems": [
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          "abnormality-of-the-immune-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/decreased-total-cd4-t-cell-proportion"
      },
      {
        "slug": "gastrointestinal-hemorrhage",
        "name": "Gastrointestinal bleeding",
        "systems": [
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          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/gastrointestinal-hemorrhage"
      },
      {
        "slug": "hyperuricemia",
        "name": "High blood uric acid level",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hyperuricemia"
      },
      {
        "slug": "increased-circulating-lactate-dehydrogenase-concentration",
        "name": "Increased circulating lactate dehydrogenase concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/increased-circulating-lactate-dehydrogenase-concentration"
      },
      {
        "slug": "intestinal-obstruction",
        "name": "Intestinal obstruction",
        "systems": [
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        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/intestinal-obstruction"
      },
      {
        "slug": "neoplasm-of-the-oral-cavity",
        "name": "Mouth tumor",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-digestive-system",
          "neoplasm"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/neoplasm-of-the-oral-cavity"
      },
      {
        "slug": "nausea-and-vomiting",
        "name": "Nausea and vomiting",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/nausea-and-vomiting"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}