{
  "url": "https://dantelabs.com/genes/fsip2",
  "gene": {
    "slug": "fsip2",
    "symbol": "FSIP2",
    "name": "fibrous sheath interacting protein 2",
    "hgnc": "HGNC:21675",
    "summary": null,
    "location": "2q32.1",
    "locusType": "gene with protein product",
    "aliases": [
      "FLJ34780"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000188738",
    "entrezId": 401024,
    "omim": [
      "615796"
    ],
    "uniprot": [
      "Q5CZC0"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "2",
      "start": 185738804,
      "end": 185833290,
      "strand": "+",
      "ensemblTranscript": "ENST00000424728.6",
      "refseqTranscript": "NM_173651.4",
      "ensemblProtein": "ENSP00000401306.1",
      "refseqProtein": "NP_775922.3",
      "exons": [
        {
          "start": 185738804,
          "end": 185738993
        },
        {
          "start": 185739346,
          "end": 185739471
        },
        {
          "start": 185743133,
          "end": 185743294
        },
        {
          "start": 185744322,
          "end": 185744411
        },
        {
          "start": 185745429,
          "end": 185745568
        },
        {
          "start": 185746669,
          "end": 185746810
        },
        {
          "start": 185747313,
          "end": 185747423
        },
        {
          "start": 185753722,
          "end": 185753842
        },
        {
          "start": 185756192,
          "end": 185756278
        },
        {
          "start": 185760988,
          "end": 185761103
        },
        {
          "start": 185761972,
          "end": 185762017
        },
        {
          "start": 185763183,
          "end": 185763289
        },
        {
          "start": 185764502,
          "end": 185764565
        },
        {
          "start": 185782705,
          "end": 185782762
        },
        {
          "start": 185786252,
          "end": 185786288
        },
        {
          "start": 185788643,
          "end": 185797526
        },
        {
          "start": 185799697,
          "end": 185809133
        },
        {
          "start": 185813545,
          "end": 185814042
        },
        {
          "start": 185815371,
          "end": 185815471
        },
        {
          "start": 185824434,
          "end": 185824480
        },
        {
          "start": 185828156,
          "end": 185828199
        },
        {
          "start": 185831813,
          "end": 185831882
        },
        {
          "start": 185833090,
          "end": 185833290
        }
      ],
      "cds": {
        "start": 185738895,
        "end": 185833226
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "2",
      "start": 186603355,
      "end": 186698017,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 185286047,
      "end": 186286046,
      "genes": [],
      "truncated": false
    },
    "reports": [
      {
        "slug": "male-infertility",
        "name": "Male Infertility",
        "diseases": [
          {
            "mondoId": "MONDO:0005372",
            "name": "Male Infertility",
            "genes": 41,
            "inheritance": null,
            "description": "The inability of the male to effect fertilization of an ovum after a specified period of unprotected intercourse. Male sterility is permanent infertility.",
            "management": null,
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/conditions/male-infertility"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "absent-sperm-axoneme-central-pair-complex",
        "name": "Absent sperm axoneme central pair complex",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/absent-sperm-axoneme-central-pair-complex"
      },
      {
        "slug": "absent-sperm-flagella",
        "name": "Absent sperm flagella",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/absent-sperm-flagella"
      },
      {
        "slug": "coiled-sperm-flagella",
        "name": "Coiled sperm flagella",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/coiled-sperm-flagella"
      },
      {
        "slug": "irregularly-shaped-sperm-tail",
        "name": "Irregularly shaped sperm tail",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/irregularly-shaped-sperm-tail"
      },
      {
        "slug": "male-infertility",
        "name": "Male infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/male-infertility"
      },
      {
        "slug": "reduced-sperm-motility",
        "name": "Reduced sperm motility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/reduced-sperm-motility"
      },
      {
        "slug": "short-sperm-flagella",
        "name": "Short sperm flagella",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-sperm-flagella"
      }
    ],
    "related": [
      {
        "slug": "actl9",
        "symbol": "ACTL9",
        "name": "actin like 9",
        "shared": 1,
        "url": "https://dantelabs.com/genes/actl9"
      },
      {
        "slug": "armc2",
        "symbol": "ARMC2",
        "name": "armadillo repeat containing 2",
        "shared": 1,
        "url": "https://dantelabs.com/genes/armc2"
      },
      {
        "slug": "aurkc",
        "symbol": "AURKC",
        "name": "aurora kinase C",
        "shared": 1,
        "url": "https://dantelabs.com/genes/aurkc"
      },
      {
        "slug": "bcorl1",
        "symbol": "BCORL1",
        "name": "BCL6 corepressor like 1",
        "shared": 1,
        "url": "https://dantelabs.com/genes/bcorl1"
      },
      {
        "slug": "cfap251",
        "symbol": "CFAP251",
        "name": "cilia and flagella associated protein 251",
        "shared": 1,
        "url": "https://dantelabs.com/genes/cfap251"
      },
      {
        "slug": "cfap43",
        "symbol": "CFAP43",
        "name": "cilia and flagella associated protein 43",
        "shared": 1,
        "url": "https://dantelabs.com/genes/cfap43"
      },
      {
        "slug": "dmc1",
        "symbol": "DMC1",
        "name": "DNA meiotic recombinase 1",
        "shared": 1,
        "url": "https://dantelabs.com/genes/dmc1"
      },
      {
        "slug": "dmrt1",
        "symbol": "DMRT1",
        "name": "doublesex and mab-3 related transcription factor 1",
        "shared": 1,
        "url": "https://dantelabs.com/genes/dmrt1"
      },
      {
        "slug": "dnah1",
        "symbol": "DNAH1",
        "name": "dynein axonemal heavy chain 1",
        "shared": 1,
        "url": "https://dantelabs.com/genes/dnah1"
      },
      {
        "slug": "dnah10",
        "symbol": "DNAH10",
        "name": "dynein axonemal heavy chain 10",
        "shared": 1,
        "url": "https://dantelabs.com/genes/dnah10"
      },
      {
        "slug": "dnah12",
        "symbol": "DNAH12",
        "name": "dynein axonemal heavy chain 12",
        "shared": 1,
        "url": "https://dantelabs.com/genes/dnah12"
      },
      {
        "slug": "dnah17",
        "symbol": "DNAH17",
        "name": "dynein axonemal heavy chain 17",
        "shared": 1,
        "url": "https://dantelabs.com/genes/dnah17"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}