{
  "url": "https://dantelabs.com/traits/thyroid-hyperplasia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "thyroid-hyperplasia",
    "id": "HP:0008249",
    "name": "Large thyroid",
    "label": "Thyroid hyperplasia",
    "definition": "Hyperplasia of the thyroid gland.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-thyroid-morphology",
        "name": "Abnormal shape of thyroid gland",
        "url": "https://dantelabs.com/traits/abnormal-thyroid-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "thyroid-c-cell-hyperplasia",
        "name": "Thyroid C cell hyperplasia",
        "genes": 2,
        "url": "https://dantelabs.com/traits/thyroid-c-cell-hyperplasia"
      },
      {
        "slug": "thyroid-follicular-hyperplasia",
        "name": "Thyroid follicular hyperplasia",
        "genes": 1,
        "url": "https://dantelabs.com/traits/thyroid-follicular-hyperplasia"
      }
    ],
    "genes": [
      {
        "slug": "tg",
        "symbol": "TG",
        "hgnc": "HGNC:11764",
        "name": "thyroglobulin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tg"
      },
      {
        "slug": "tshr",
        "symbol": "TSHR",
        "hgnc": "HGNC:12373",
        "name": "thyroid stimulating hormone receptor",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/tshr"
      }
    ]
  }
}