{
  "url": "https://dantelabs.com/traits/persistent-fetal-circulation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "persistent-fetal-circulation",
    "id": "HP:0011726",
    "name": "Persistent fetal circulation",
    "definition": "Systemic desaturation of a liveborn baby resulting from persistent pulmonary hypertension with a patent ductus arteriosus and patent foramen ovale, such that the circulation in postnatal life follows the fetal course.",
    "synonyms": [
      "Persistent foetal circulation"
    ],
    "systems": [
      {
        "slug": "abnormality-of-prenatal-development-or-birth",
        "name": "Abnormality of prenatal development or birth",
        "url": "https://dantelabs.com/traits/abnormality-of-prenatal-development-or-birth"
      },
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-fetal-cardiovascular-physiology",
        "name": "Abnormal fetal cardiovascular physiology",
        "url": "https://dantelabs.com/traits/abnormal-fetal-cardiovascular-physiology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "uqcrfs1",
        "symbol": "UQCRFS1",
        "hgnc": "HGNC:12587",
        "name": "ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/uqcrfs1"
      }
    ]
  }
}