{
  "url": "https://dantelabs.com/traits/peripheral-hypomyelination",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "peripheral-hypomyelination",
    "id": "HP:0007182",
    "name": "Peripheral hypomyelination",
    "definition": "Reduced amount of myelin in the nervous system resulting from defective myelinogenesis in the peripheral nervous system.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-peripheral-myelination",
        "name": "Abnormal peripheral myelination",
        "url": "https://dantelabs.com/traits/abnormal-peripheral-myelination"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "adcy6",
        "symbol": "ADCY6",
        "hgnc": "HGNC:237",
        "name": "adenylate cyclase 6",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adcy6"
      },
      {
        "slug": "dst",
        "symbol": "DST",
        "hgnc": "HGNC:1090",
        "name": "dystonin",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dst"
      },
      {
        "slug": "ctdp1",
        "symbol": "CTDP1",
        "hgnc": "HGNC:2498",
        "name": "CTD phosphatase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ctdp1"
      },
      {
        "slug": "dhx16",
        "symbol": "DHX16",
        "hgnc": "HGNC:2739",
        "name": "DEAH-box helicase 16",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx16"
      },
      {
        "slug": "kcnj10",
        "symbol": "KCNJ10",
        "hgnc": "HGNC:6256",
        "name": "potassium inwardly rectifying channel subfamily J member 10",
        "frequency": "occasional",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnj10"
      },
      {
        "slug": "egr2",
        "symbol": "EGR2",
        "hgnc": "HGNC:3239",
        "name": "early growth response 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/egr2"
      },
      {
        "slug": "fgd4",
        "symbol": "FGD4",
        "hgnc": "HGNC:19125",
        "name": "FYVE, RhoGEF and PH domain containing 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgd4"
      },
      {
        "slug": "fig4",
        "symbol": "FIG4",
        "hgnc": "HGNC:16873",
        "name": "FIG4 phosphoinositide 5-phosphatase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fig4"
      },
      {
        "slug": "hk1",
        "symbol": "HK1",
        "hgnc": "HGNC:4922",
        "name": "hexokinase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hk1"
      },
      {
        "slug": "sox10",
        "symbol": "SOX10",
        "hgnc": "HGNC:11190",
        "name": "SRY-box transcription factor 10",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox10"
      }
    ]
  }
}