{
  "url": "https://dantelabs.com/traits/motor-tics",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "motor-tics",
    "id": "HP:0100034",
    "name": "Motor tics",
    "definition": "Movement-based tics affecting discrete muscle groups.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "tics",
        "name": "Tic disorder",
        "url": "https://dantelabs.com/traits/tics"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cep152",
        "symbol": "CEP152",
        "hgnc": "HGNC:29298",
        "name": "centrosomal protein 152",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep152"
      },
      {
        "slug": "coasy",
        "symbol": "COASY",
        "hgnc": "HGNC:29932",
        "name": "Coenzyme A synthase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/coasy"
      },
      {
        "slug": "gria1",
        "symbol": "GRIA1",
        "hgnc": "HGNC:4571",
        "name": "glutamate ionotropic receptor AMPA type subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gria1"
      },
      {
        "slug": "kcnn2",
        "symbol": "KCNN2",
        "hgnc": "HGNC:6291",
        "name": "potassium calcium-activated channel subfamily N member 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnn2"
      },
      {
        "slug": "vps13a",
        "symbol": "VPS13A",
        "hgnc": "HGNC:1908",
        "name": "vacuolar protein sorting 13 homolog A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps13a"
      },
      {
        "slug": "gnb1",
        "symbol": "GNB1",
        "hgnc": "HGNC:4396",
        "name": "G protein subunit beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnb1"
      },
      {
        "slug": "hnrnpc",
        "symbol": "HNRNPC",
        "hgnc": "HGNC:5035",
        "name": "heterogeneous nuclear ribonucleoprotein C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hnrnpc"
      },
      {
        "slug": "pank2",
        "symbol": "PANK2",
        "hgnc": "HGNC:15894",
        "name": "pantothenate kinase 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pank2"
      },
      {
        "slug": "pdgfb",
        "symbol": "PDGFB",
        "hgnc": "HGNC:8800",
        "name": "platelet derived growth factor subunit B",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pdgfb"
      },
      {
        "slug": "hdc",
        "symbol": "HDC",
        "hgnc": "HGNC:4855",
        "name": "histidine decarboxylase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hdc"
      },
      {
        "slug": "ptchd1",
        "symbol": "PTCHD1",
        "hgnc": "HGNC:26392",
        "name": "patched domain containing 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptchd1"
      },
      {
        "slug": "slitrk1",
        "symbol": "SLITRK1",
        "hgnc": "HGNC:20297",
        "name": "SLIT and NTRK like family member 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slitrk1"
      }
    ]
  }
}