{
  "url": "https://dantelabs.com/traits/hyperplastic-colonic-polyposis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hyperplastic-colonic-polyposis",
    "id": "HP:0012183",
    "name": "Hyperplastic colonic polyposis",
    "definition": "Presence of multiple hyperplastic polyps in the colon. Hyperplastic polyps are generally about 5 mm in size and show hyperplastic mucosal proliferation.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "large-intestinal-polyposis",
        "name": "Large intestinal polyposis",
        "url": "https://dantelabs.com/traits/large-intestinal-polyposis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "bmpr1a",
        "symbol": "BMPR1A",
        "hgnc": "HGNC:1076",
        "name": "bone morphogenetic protein receptor type 1A",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/bmpr1a"
      },
      {
        "slug": "grem1",
        "symbol": "GREM1",
        "hgnc": "HGNC:2001",
        "name": "gremlin 1, DAN family BMP antagonist",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/grem1"
      }
    ]
  }
}