{
  "url": "https://dantelabs.com/traits/hydatidiform-mole",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hydatidiform-mole",
    "id": "HP:0032192",
    "name": "Hydatidiform mole",
    "definition": "Hydatidiform mole (HM) is an aberrant human pregnancy with absence of, or abnormal embryonic development, hydropic degeneration of chorionic villi, and excessive proliferation of the trophoblast.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-prenatal-development-or-birth",
        "name": "Abnormality of prenatal development or birth",
        "url": "https://dantelabs.com/traits/abnormality-of-prenatal-development-or-birth"
      }
    ],
    "broader": [
      {
        "slug": "abnormalities-of-placenta-or-umbilical-cord",
        "name": "Abnormalities of placenta or umbilical cord",
        "url": "https://dantelabs.com/traits/abnormalities-of-placenta-or-umbilical-cord"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "khdc3l",
        "symbol": "KHDC3L",
        "hgnc": "HGNC:33699",
        "name": "KH domain containing 3 like, subcortical maternal complex member",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/khdc3l"
      },
      {
        "slug": "mei1",
        "symbol": "MEI1",
        "hgnc": "HGNC:28613",
        "name": "meiotic double-stranded break formation protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mei1"
      },
      {
        "slug": "nlrp7",
        "symbol": "NLRP7",
        "hgnc": "HGNC:22947",
        "name": "NLR family pyrin domain containing 7",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nlrp7"
      },
      {
        "slug": "top6bl",
        "symbol": "TOP6BL",
        "hgnc": "HGNC:26197",
        "name": "TOP6B like initiator of meiotic double strand breaks",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/top6bl"
      }
    ]
  }
}