{
  "url": "https://dantelabs.com/traits/flat-acetabular-roof",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "flat-acetabular-roof",
    "id": "HP:0003180",
    "name": "Flat acetabular roof",
    "definition": "Flattening of the superior part of the acetabulum, which is a cup-shaped cavity at the base of the hipbone into which the ball-shaped head of the femur fits. The acetabular roof thereby appears horizontal rather than arched, as it normally does.",
    "synonyms": [
      "Acetabular angle flat",
      "Flat acetabular roofs",
      "Flattened acetabular roof",
      "Horizontal acetabulae",
      "Horizontal acetabular roof",
      "Horizontal acetabular roofs"
    ],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-acetabulum-morphology",
        "name": "Abnormality of the hipbone socket",
        "url": "https://dantelabs.com/traits/abnormal-acetabulum-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "bnip1",
        "symbol": "BNIP1",
        "hgnc": "HGNC:1082",
        "name": "BCL2 interacting protein 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bnip1"
      },
      {
        "slug": "cant1",
        "symbol": "CANT1",
        "hgnc": "HGNC:19721",
        "name": "calcium activated nucleotidase 1",
        "frequency": "obligate",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cant1"
      },
      {
        "slug": "col2a1",
        "symbol": "COL2A1",
        "hgnc": "HGNC:2200",
        "name": "collagen type II alpha 1 chain",
        "frequency": "obligate",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/col2a1"
      },
      {
        "slug": "csgalnact1",
        "symbol": "CSGALNACT1",
        "hgnc": "HGNC:24290",
        "name": "chondroitin sulfate N-acetylgalactosaminyltransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/csgalnact1"
      },
      {
        "slug": "gnpnat1",
        "symbol": "GNPNAT1",
        "hgnc": "HGNC:19980",
        "name": "glucosamine-phosphate N-acetyltransferase 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnpnat1"
      },
      {
        "slug": "pam16",
        "symbol": "PAM16",
        "hgnc": "HGNC:29679",
        "name": "presequence translocase associated motor 16",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pam16"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "rab33b",
        "symbol": "RAB33B",
        "hgnc": "HGNC:16075",
        "name": "RAB33B, member RAS oncogene family",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab33b"
      },
      {
        "slug": "slc35d1",
        "symbol": "SLC35D1",
        "hgnc": "HGNC:20800",
        "name": "solute carrier family 35 member D1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc35d1"
      },
      {
        "slug": "dym",
        "symbol": "DYM",
        "hgnc": "HGNC:21317",
        "name": "dymeclin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dym"
      },
      {
        "slug": "fig4",
        "symbol": "FIG4",
        "hgnc": "HGNC:16873",
        "name": "FIG4 phosphoinositide 5-phosphatase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fig4"
      },
      {
        "slug": "trpv4",
        "symbol": "TRPV4",
        "hgnc": "HGNC:18083",
        "name": "transient receptor potential cation channel subfamily V member 4",
        "frequency": "frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/trpv4"
      },
      {
        "slug": "cog1",
        "symbol": "COG1",
        "hgnc": "HGNC:6545",
        "name": "component of oligomeric golgi complex 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cog1"
      },
      {
        "slug": "comp",
        "symbol": "COMP",
        "hgnc": "HGNC:2227",
        "name": "cartilage oligomeric matrix protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/comp"
      },
      {
        "slug": "fgfr3",
        "symbol": "FGFR3",
        "hgnc": "HGNC:3690",
        "name": "fibroblast growth factor receptor 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr3"
      },
      {
        "slug": "bgn",
        "symbol": "BGN",
        "hgnc": "HGNC:1044",
        "name": "biglycan",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bgn"
      },
      {
        "slug": "ccn2",
        "symbol": "CCN2",
        "hgnc": "HGNC:2500",
        "name": "cellular communication network factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccn2"
      },
      {
        "slug": "cep120",
        "symbol": "CEP120",
        "hgnc": "HGNC:26690",
        "name": "centrosomal protein 120",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep120"
      },
      {
        "slug": "chd4",
        "symbol": "CHD4",
        "hgnc": "HGNC:1919",
        "name": "chromodomain helicase DNA binding protein 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chd4"
      },
      {
        "slug": "flnb",
        "symbol": "FLNB",
        "hgnc": "HGNC:3755",
        "name": "filamin B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnb"
      },
      {
        "slug": "gnptab",
        "symbol": "GNPTAB",
        "hgnc": "HGNC:29670",
        "name": "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnptab"
      },
      {
        "slug": "gpx4",
        "symbol": "GPX4",
        "hgnc": "HGNC:4556",
        "name": "glutathione peroxidase 4",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gpx4"
      },
      {
        "slug": "ift52",
        "symbol": "IFT52",
        "hgnc": "HGNC:15901",
        "name": "intraflagellar transport 52",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift52"
      },
      {
        "slug": "inppl1",
        "symbol": "INPPL1",
        "hgnc": "HGNC:6080",
        "name": "inositol polyphosphate phosphatase like 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/inppl1"
      },
      {
        "slug": "matn3",
        "symbol": "MATN3",
        "hgnc": "HGNC:6909",
        "name": "matrilin 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/matn3"
      },
      {
        "slug": "nans",
        "symbol": "NANS",
        "hgnc": "HGNC:19237",
        "name": "N-acetylneuraminate synthase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nans"
      },
      {
        "slug": "slc26a2",
        "symbol": "SLC26A2",
        "hgnc": "HGNC:10994",
        "name": "solute carrier family 26 member 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc26a2"
      },
      {
        "slug": "trip11",
        "symbol": "TRIP11",
        "hgnc": "HGNC:12305",
        "name": "thyroid hormone receptor interactor 11",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trip11"
      },
      {
        "slug": "wdr35",
        "symbol": "WDR35",
        "hgnc": "HGNC:29250",
        "name": "WD repeat domain 35",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wdr35"
      },
      {
        "slug": "xylt1",
        "symbol": "XYLT1",
        "hgnc": "HGNC:15516",
        "name": "xylosyltransferase 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/xylt1"
      }
    ]
  }
}