{
  "url": "https://dantelabs.com/traits/cold-urticaria",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "cold-urticaria",
    "id": "HP:0410135",
    "name": "Cold urticaria",
    "definition": "Urticaria may be caused by cold temperatures.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "physical-urticaria",
        "name": "Physical urticaria",
        "url": "https://dantelabs.com/traits/physical-urticaria"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "plcg2",
        "symbol": "PLCG2",
        "hgnc": "HGNC:9066",
        "name": "phospholipase C gamma 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plcg2"
      },
      {
        "slug": "carmil2",
        "symbol": "CARMIL2",
        "hgnc": "HGNC:27089",
        "name": "capping protein regulator and myosin 1 linker 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/carmil2"
      },
      {
        "slug": "nlrp3",
        "symbol": "NLRP3",
        "hgnc": "HGNC:16400",
        "name": "NLR family pyrin domain containing 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nlrp3"
      }
    ]
  }
}