{
  "url": "https://dantelabs.com/traits/block-vertebrae",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "block-vertebrae",
    "id": "HP:0003305",
    "name": "Block vertebrae",
    "definition": "Congenital synostosis between two or more adjacent vertebrae (partial or complete fusion of adjacent vertabral bodies).",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "vertebral-fusion",
        "name": "Vertebral fusion",
        "url": "https://dantelabs.com/traits/vertebral-fusion"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "zic3",
        "symbol": "ZIC3",
        "hgnc": "HGNC:12874",
        "name": "Zic family zinc finger 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/zic3"
      },
      {
        "slug": "dll3",
        "symbol": "DLL3",
        "hgnc": "HGNC:2909",
        "name": "delta like canonical Notch ligand 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dll3"
      },
      {
        "slug": "flnb",
        "symbol": "FLNB",
        "hgnc": "HGNC:3755",
        "name": "filamin B",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnb"
      },
      {
        "slug": "hes7",
        "symbol": "HES7",
        "hgnc": "HGNC:15977",
        "name": "hes family bHLH transcription factor 7",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hes7"
      },
      {
        "slug": "mesp2",
        "symbol": "MESP2",
        "hgnc": "HGNC:29659",
        "name": "mesoderm posterior bHLH transcription factor 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mesp2"
      },
      {
        "slug": "sf3b2",
        "symbol": "SF3B2",
        "hgnc": "HGNC:10769",
        "name": "splicing factor 3b subunit 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sf3b2"
      }
    ]
  }
}