{
  "url": "https://dantelabs.com/traits/abnormal-circulating-testosterone-concentration",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-circulating-testosterone-concentration",
    "id": "HP:0030087",
    "name": "Abnormal testosterone level",
    "label": "Abnormal circulating testosterone concentration",
    "definition": "An anomalous concentration of testosterone in the blood.",
    "synonyms": [
      "Abnormal serum testosterone level"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-androgen-level",
        "name": "Abnormal circulating androgen level",
        "url": "https://dantelabs.com/traits/abnormal-circulating-androgen-level"
      }
    ],
    "narrower": [
      {
        "slug": "decreased-serum-testosterone-concentration",
        "name": "Decreased serum testosterone level",
        "genes": 71,
        "url": "https://dantelabs.com/traits/decreased-serum-testosterone-concentration"
      },
      {
        "slug": "increased-serum-testosterone-level",
        "name": "Increased testosterone",
        "genes": 11,
        "url": "https://dantelabs.com/traits/increased-serum-testosterone-level"
      }
    ],
    "genes": [
      {
        "slug": "nr3c1",
        "symbol": "NR3C1",
        "hgnc": "HGNC:7978",
        "name": "nuclear receptor subfamily 3 group C member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr3c1"
      },
      {
        "slug": "esr1",
        "symbol": "ESR1",
        "hgnc": "HGNC:3467",
        "name": "estrogen receptor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/esr1"
      }
    ]
  }
}