{
  "url": "https://dantelabs.com/fr/genes/u2af1",
  "gene": {
    "slug": "u2af1",
    "symbol": "U2AF1",
    "name": "U2 small nuclear RNA auxiliary factor 1",
    "hgnc": "HGNC:12453",
    "summary": null,
    "location": "21q22.3",
    "locusType": "gene with protein product",
    "aliases": [
      "U2AF35",
      "RNU2AF1",
      "RN"
    ],
    "previousSymbols": [
      "U2AFBP"
    ],
    "ensemblId": "ENSG00000160201",
    "entrezId": 7307,
    "omim": [
      "191317"
    ],
    "uniprot": [
      "Q01081"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "21",
      "start": 43092956,
      "end": 43107570,
      "strand": "-",
      "ensemblTranscript": "ENST00000291552.9",
      "refseqTranscript": "NM_006758.3",
      "ensemblProtein": "ENSP00000291552.4",
      "refseqProtein": "NP_006749.1",
      "exons": [
        {
          "start": 43092956,
          "end": 43093249
        },
        {
          "start": 43094471,
          "end": 43094563
        },
        {
          "start": 43094655,
          "end": 43094788
        },
        {
          "start": 43095438,
          "end": 43095536
        },
        {
          "start": 43095694,
          "end": 43095743
        },
        {
          "start": 43100453,
          "end": 43100519
        },
        {
          "start": 43104315,
          "end": 43104402
        },
        {
          "start": 43107451,
          "end": 43107570
        }
      ],
      "cds": {
        "start": 43093102,
        "end": 43107494
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "21",
      "start": 44513066,
      "end": 44527697,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 42600263,
      "end": 43600262,
      "genes": [
        {
          "symbol": "PDE9A",
          "ensemblId": "ENSG00000160191",
          "biotype": "protein_coding",
          "start": 42653584,
          "end": 42776512,
          "strand": "+",
          "slug": "pde9a"
        },
        {
          "symbol": "WDR4",
          "ensemblId": "ENSG00000160193",
          "biotype": "protein_coding",
          "start": 42843013,
          "end": 42879583,
          "strand": "-",
          "slug": "wdr4"
        },
        {
          "symbol": "NDUFV3",
          "ensemblId": "ENSG00000160194",
          "biotype": "protein_coding",
          "start": 42879644,
          "end": 42913304,
          "strand": "+",
          "slug": "ndufv3"
        },
        {
          "symbol": "ERVH48-1",
          "ensemblId": "ENSG00000233056",
          "biotype": "protein_coding",
          "start": 42916803,
          "end": 42925630,
          "strand": "-",
          "slug": "ervh48-1"
        },
        {
          "symbol": "PKNOX1",
          "ensemblId": "ENSG00000160199",
          "biotype": "protein_coding",
          "start": 42974328,
          "end": 43034494,
          "strand": "+",
          "slug": "pknox1"
        },
        {
          "symbol": "CBS",
          "ensemblId": "ENSG00000160200",
          "biotype": "protein_coding",
          "start": 43050900,
          "end": 43076943,
          "strand": "-",
          "slug": "cbs"
        },
        {
          "symbol": "CRYAA",
          "ensemblId": "ENSG00000160202",
          "biotype": "protein_coding",
          "start": 43169008,
          "end": 43172810,
          "strand": "+",
          "slug": "cryaa"
        },
        {
          "symbol": "SIK1",
          "ensemblId": "ENSG00000142178",
          "biotype": "protein_coding",
          "start": 43414483,
          "end": 43427137,
          "strand": "-",
          "slug": "sik1"
        },
        {
          "symbol": "HSF2BP",
          "ensemblId": "ENSG00000160207",
          "biotype": "protein_coding",
          "start": 43529186,
          "end": 43659524,
          "strand": "-",
          "slug": "hsf2bp"
        },
        {
          "symbol": "H2BC12L",
          "ensemblId": "ENSG00000234289",
          "biotype": "protein_coding",
          "start": 43565182,
          "end": 43565648,
          "strand": "+",
          "slug": "h2bc12l"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}