{
  "url": "https://dantelabs.com/fr/genes/ssx1",
  "gene": {
    "slug": "ssx1",
    "symbol": "SSX1",
    "name": "SSX family member 1",
    "hgnc": "HGNC:11335",
    "summary": null,
    "location": "Xp11.23",
    "locusType": "gene with protein product",
    "aliases": [
      "CT5.1"
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    "previousSymbols": [],
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    "uniprot": [
      "Q16384"
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      "release": "v1.5",
      "chrom": "X",
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      "strand": "+",
      "ensemblTranscript": "ENST00000376919.4",
      "refseqTranscript": "NM_005635.4",
      "ensemblProtein": "ENSP00000366118.3",
      "refseqProtein": "NP_005626.1",
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      "cds": {
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      "build": "GRCh37",
      "release": "87",
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      "strand": "+"
    },
    "neighbourhood": {
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      "genes": [
        {
          "symbol": "ZNF81",
          "ensemblId": "ENSG00000197779",
          "biotype": "protein_coding",
          "start": 47836471,
          "end": 48003066,
          "strand": "+",
          "slug": "znf81"
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        {
          "symbol": "ZNF182",
          "ensemblId": "ENSG00000147118",
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        {
          "symbol": "ZNF630",
          "ensemblId": "ENSG00000221994",
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          "strand": "-",
          "slug": "znf630"
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        {
          "symbol": "SPACA5",
          "ensemblId": "ENSG00000171489",
          "biotype": "protein_coding",
          "start": 48004336,
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          "slug": "spaca5"
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        {
          "symbol": "SPACA5B",
          "ensemblId": "ENSG00000171478",
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        },
        {
          "symbol": "SSX5",
          "ensemblId": "ENSG00000165583",
          "biotype": "protein_coding",
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          "slug": "ssx5"
        },
        {
          "symbol": "SSX3",
          "ensemblId": "ENSG00000165584",
          "biotype": "protein_coding",
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          "strand": "-",
          "slug": "ssx3"
        },
        {
          "symbol": "SSX4",
          "ensemblId": "ENSG00000268009",
          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "ssx4"
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        {
          "symbol": "SSX4B",
          "ensemblId": "ENSG00000269791",
          "biotype": "protein_coding",
          "start": 48402082,
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          "strand": "-",
          "slug": "ssx4b"
        },
        {
          "symbol": "SLC38A5",
          "ensemblId": "ENSG00000017483",
          "biotype": "protein_coding",
          "start": 48458536,
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          "strand": "-",
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        },
        {
          "symbol": "FTSJ1",
          "ensemblId": "ENSG00000068438",
          "biotype": "protein_coding",
          "start": 48476021,
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          "strand": "+",
          "slug": "ftsj1"
        },
        {
          "symbol": "PORCN",
          "ensemblId": "ENSG00000102312",
          "biotype": "protein_coding",
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          "slug": "porcn"
        },
        {
          "symbol": "EBP",
          "ensemblId": "ENSG00000147155",
          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "ebp"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000286268",
          "biotype": "protein_coding",
          "start": 48521806,
          "end": 48545469,
          "strand": "+"
        },
        {
          "symbol": "TBC1D25",
          "ensemblId": "ENSG00000068354",
          "biotype": "protein_coding",
          "start": 48539623,
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          "strand": "+",
          "slug": "tbc1d25"
        },
        {
          "symbol": "RBM3",
          "ensemblId": "ENSG00000102317",
          "biotype": "protein_coding",
          "start": 48574056,
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          "strand": "+",
          "slug": "rbm3"
        },
        {
          "symbol": "WDR13",
          "ensemblId": "ENSG00000101940",
          "biotype": "protein_coding",
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          "strand": "+",
          "slug": "wdr13"
        },
        {
          "symbol": "WAS",
          "ensemblId": "ENSG00000015285",
          "biotype": "protein_coding",
          "start": 48676593,
          "end": 48691431,
          "strand": "+",
          "slug": "was"
        },
        {
          "symbol": "SUV39H1",
          "ensemblId": "ENSG00000101945",
          "biotype": "protein_coding",
          "start": 48695554,
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          "strand": "+",
          "slug": "suv39h1"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "male-infertility",
        "name": "Infertilité masculine",
        "diseases": [
          {
            "mondoId": "MONDO:0005372",
            "name": "Infertilité masculine",
            "genes": 41,
            "inheritance": null,
            "description": "Incapacité pour l'homme de féconder un ovocyte après une période donnée de rapports sexuels non protégés. La stérilité masculine correspond à une infertilité permanente.",
            "management": null,
            "evidence": {
              "gencc": [
                "Labcorp Genetics (formerly Invitae)"
              ],
              "acmgSf": false,
              "inheritance": []
            },
            "sameAsReport": true,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/fr/conditions/male-infertility"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "absent-sperm-flagella",
        "name": "Absent sperm flagella",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/absent-sperm-flagella"
      },
      {
        "slug": "coiled-sperm-flagella",
        "name": "Coiled sperm flagella",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/coiled-sperm-flagella"
      },
      {
        "slug": "irregularly-shaped-sperm-tail",
        "name": "Irregularly shaped sperm tail",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/irregularly-shaped-sperm-tail"
      },
      {
        "slug": "male-infertility",
        "name": "Male infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/male-infertility"
      },
      {
        "slug": "reduced-progressive-sperm-motility",
        "name": "Reduced progressive sperm motility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/reduced-progressive-sperm-motility"
      },
      {
        "slug": "reduced-sperm-motility",
        "name": "Reduced sperm motility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/reduced-sperm-motility"
      },
      {
        "slug": "short-sperm-flagella",
        "name": "Short sperm flagella",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/short-sperm-flagella"
      },
      {
        "slug": "synovial-sarcoma",
        "name": "Synovial sarcoma",
        "systems": [
          "neoplasm"
        ],
        "url": "https://dantelabs.com/traits/synovial-sarcoma"
      }
    ],
    "related": [
      {
        "slug": "actl9",
        "symbol": "ACTL9",
        "name": "actin like 9",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/actl9"
      },
      {
        "slug": "armc2",
        "symbol": "ARMC2",
        "name": "armadillo repeat containing 2",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/armc2"
      },
      {
        "slug": "aurkc",
        "symbol": "AURKC",
        "name": "aurora kinase C",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/aurkc"
      },
      {
        "slug": "bcorl1",
        "symbol": "BCORL1",
        "name": "BCL6 corepressor like 1",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/bcorl1"
      },
      {
        "slug": "cfap251",
        "symbol": "CFAP251",
        "name": "cilia and flagella associated protein 251",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/cfap251"
      },
      {
        "slug": "cfap43",
        "symbol": "CFAP43",
        "name": "cilia and flagella associated protein 43",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/cfap43"
      },
      {
        "slug": "dmc1",
        "symbol": "DMC1",
        "name": "DNA meiotic recombinase 1",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/dmc1"
      },
      {
        "slug": "dmrt1",
        "symbol": "DMRT1",
        "name": "doublesex and mab-3 related transcription factor 1",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/dmrt1"
      },
      {
        "slug": "dnah1",
        "symbol": "DNAH1",
        "name": "dynein axonemal heavy chain 1",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/dnah1"
      },
      {
        "slug": "dnah10",
        "symbol": "DNAH10",
        "name": "dynein axonemal heavy chain 10",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/dnah10"
      },
      {
        "slug": "dnah12",
        "symbol": "DNAH12",
        "name": "dynein axonemal heavy chain 12",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/dnah12"
      },
      {
        "slug": "dnah17",
        "symbol": "DNAH17",
        "name": "dynein axonemal heavy chain 17",
        "shared": 1,
        "url": "https://dantelabs.com/fr/genes/dnah17"
      }
    ],
    "sources": {
      "bundleId": "2026.10.16-c6eea6bf",
      "panel": "2026-10-16",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}