{
  "url": "https://dantelabs.com/fr/genes/rptor",
  "gene": {
    "slug": "rptor",
    "symbol": "RPTOR",
    "name": "regulatory associated protein of MTOR complex 1",
    "hgnc": "HGNC:30287",
    "summary": null,
    "location": "17q25.3",
    "locusType": "gene with protein product",
    "aliases": [
      "KOG1",
      "Mip1",
      "KIAA1303",
      "raptor"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000141564",
    "entrezId": 57521,
    "omim": [
      "607130"
    ],
    "uniprot": [
      "Q8N122"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "17",
      "start": 80544838,
      "end": 80966368,
      "strand": "+",
      "ensemblTranscript": "ENST00000306801.8",
      "refseqTranscript": "NM_020761.3",
      "ensemblProtein": "ENSP00000307272.3",
      "refseqProtein": "NP_065812.1",
      "exons": [
        {
          "start": 80544838,
          "end": 80545791
        },
        {
          "start": 80625691,
          "end": 80625793
        },
        {
          "start": 80643728,
          "end": 80643810
        },
        {
          "start": 80707841,
          "end": 80707999
        },
        {
          "start": 80730560,
          "end": 80730706
        },
        {
          "start": 80754010,
          "end": 80754185
        },
        {
          "start": 80791450,
          "end": 80791509
        },
        {
          "start": 80822201,
          "end": 80822301
        },
        {
          "start": 80823079,
          "end": 80823223
        },
        {
          "start": 80837922,
          "end": 80837997
        },
        {
          "start": 80846473,
          "end": 80846574
        },
        {
          "start": 80855464,
          "end": 80855547
        },
        {
          "start": 80857790,
          "end": 80857900
        },
        {
          "start": 80880415,
          "end": 80880489
        },
        {
          "start": 80883419,
          "end": 80883484
        },
        {
          "start": 80883781,
          "end": 80883972
        },
        {
          "start": 80885008,
          "end": 80885148
        },
        {
          "start": 80891720,
          "end": 80891837
        },
        {
          "start": 80892729,
          "end": 80892869
        },
        {
          "start": 80893707,
          "end": 80893865
        },
        {
          "start": 80908811,
          "end": 80908929
        },
        {
          "start": 80922724,
          "end": 80922827
        },
        {
          "start": 80923490,
          "end": 80923673
        },
        {
          "start": 80925370,
          "end": 80925480
        },
        {
          "start": 80940496,
          "end": 80940601
        },
        {
          "start": 80945667,
          "end": 80945781
        },
        {
          "start": 80947227,
          "end": 80947351
        },
        {
          "start": 80949443,
          "end": 80949547
        },
        {
          "start": 80957624,
          "end": 80957730
        },
        {
          "start": 80960078,
          "end": 80960205
        },
        {
          "start": 80961394,
          "end": 80961480
        },
        {
          "start": 80962461,
          "end": 80962577
        },
        {
          "start": 80962928,
          "end": 80963057
        },
        {
          "start": 80964262,
          "end": 80966368
        }
      ],
      "cds": {
        "start": 80545630,
        "end": 80964330
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "17",
      "start": 78518619,
      "end": 78940171,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 80123307,
      "end": 81387899,
      "genes": [
        {
          "symbol": "EIF4A3",
          "ensemblId": "ENSG00000141543",
          "biotype": "protein_coding",
          "start": 80132700,
          "end": 80147151,
          "strand": "-",
          "slug": "eif4a3"
        },
        {
          "symbol": "CARD14",
          "ensemblId": "ENSG00000141527",
          "biotype": "protein_coding",
          "start": 80169992,
          "end": 80216073,
          "strand": "+",
          "slug": "card14"
        },
        {
          "symbol": "SGSH",
          "ensemblId": "ENSG00000181523",
          "biotype": "protein_coding",
          "start": 80206716,
          "end": 80220928,
          "strand": "-",
          "slug": "sgsh"
        },
        {
          "symbol": "SLC26A11",
          "ensemblId": "ENSG00000181045",
          "biotype": "protein_coding",
          "start": 80219699,
          "end": 80253509,
          "strand": "+",
          "slug": "slc26a11"
        },
        {
          "symbol": "RNF213",
          "ensemblId": "ENSG00000173821",
          "biotype": "protein_coding",
          "start": 80260807,
          "end": 80398794,
          "strand": "+",
          "slug": "rnf213"
        },
        {
          "symbol": "ENDOV",
          "ensemblId": "ENSG00000173818",
          "biotype": "protein_coding",
          "start": 80415147,
          "end": 80438086,
          "strand": "+",
          "slug": "endov"
        },
        {
          "symbol": "NPTX1",
          "ensemblId": "ENSG00000171246",
          "biotype": "protein_coding",
          "start": 80466834,
          "end": 80477843,
          "strand": "-",
          "slug": "nptx1"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000289764",
          "biotype": "protein_coding",
          "start": 80545075,
          "end": 80545134,
          "strand": "+"
        },
        {
          "symbol": "CHMP6",
          "ensemblId": "ENSG00000176108",
          "biotype": "protein_coding",
          "start": 80991598,
          "end": 81031356,
          "strand": "+",
          "slug": "chmp6"
        },
        {
          "symbol": "BAIAP2",
          "ensemblId": "ENSG00000175866",
          "biotype": "protein_coding",
          "start": 81035122,
          "end": 81117434,
          "strand": "+",
          "slug": "baiap2"
        },
        {
          "symbol": "LMTK1",
          "ensemblId": "ENSG00000181409",
          "biotype": "protein_coding",
          "start": 81110487,
          "end": 81166228,
          "strand": "-",
          "slug": "lmtk1"
        },
        {
          "symbol": "PVALEF",
          "ensemblId": "ENSG00000225180",
          "biotype": "protein_coding",
          "start": 81165507,
          "end": 81183166,
          "strand": "+",
          "slug": "pvalef"
        },
        {
          "symbol": "CEP131",
          "ensemblId": "ENSG00000141577",
          "biotype": "protein_coding",
          "start": 81189583,
          "end": 81223014,
          "strand": "-",
          "slug": "cep131"
        },
        {
          "symbol": "TEPSIN",
          "ensemblId": "ENSG00000167302",
          "biotype": "protein_coding",
          "start": 81228277,
          "end": 81239095,
          "strand": "-",
          "slug": "tepsin"
        },
        {
          "symbol": "NDUFAF8",
          "ensemblId": "ENSG00000224877",
          "biotype": "protein_coding",
          "start": 81239305,
          "end": 81241310,
          "strand": "+",
          "slug": "ndufaf8"
        },
        {
          "symbol": "SLC38A10",
          "ensemblId": "ENSG00000157637",
          "biotype": "protein_coding",
          "start": 81244811,
          "end": 81295567,
          "strand": "-",
          "slug": "slc38a10"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}