{
  "url": "https://dantelabs.com/fr/genes/racgap1",
  "gene": {
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    "symbol": "RACGAP1",
    "name": "Rac GTPase activating protein 1",
    "hgnc": "HGNC:9804",
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    "location": "12q13.12",
    "locusType": "gene with protein product",
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      "CYK4"
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    "previousSymbols": [],
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    "entrezId": 29127,
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    "uniprot": [
      "Q9H0H5"
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      "release": "v1.5",
      "chrom": "12",
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      "ensemblTranscript": "ENST00000312377.10",
      "refseqTranscript": "NM_001319999.2",
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    },
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          "symbol": "SPATS2",
          "ensemblId": "ENSG00000123352",
          "biotype": "protein_coding",
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        {
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        {
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        {
          "symbol": "PRPF40B",
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        {
          "symbol": "FAM186B",
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        {
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        {
          "symbol": "TMBIM6",
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        {
          "symbol": "NCKAP5L",
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        {
          "symbol": "BCDIN3D",
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        {
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          "slug": "faim2"
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        {
          "symbol": "AQP2",
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        {
          "symbol": "AQP5",
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          "biotype": "protein_coding",
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        {
          "symbol": "AQP6",
          "ensemblId": "ENSG00000086159",
          "biotype": "protein_coding",
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          "strand": "+",
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        {
          "symbol": "ASIC1",
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        {
          "symbol": "SMARCD1",
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        {
          "symbol": "GPD1",
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          "biotype": "protein_coding",
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        {
          "symbol": "COX14",
          "ensemblId": "ENSG00000178449",
          "biotype": "protein_coding",
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          "slug": "cox14"
        },
        {
          "symbol": "CERS5",
          "ensemblId": "ENSG00000139624",
          "biotype": "protein_coding",
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          "end": 50167533,
          "strand": "-",
          "slug": "cers5"
        },
        {
          "symbol": "LIMA1",
          "ensemblId": "ENSG00000050405",
          "biotype": "protein_coding",
          "start": 50175788,
          "end": 50283550,
          "strand": "-",
          "slug": "lima1"
        },
        {
          "symbol": "FAM186A",
          "ensemblId": "ENSG00000185958",
          "biotype": "protein_coding",
          "start": 50326230,
          "end": 50396622,
          "strand": "-",
          "slug": "fam186a"
        },
        {
          "symbol": "LARP4",
          "ensemblId": "ENSG00000161813",
          "biotype": "protein_coding",
          "start": 50392383,
          "end": 50480007,
          "strand": "+",
          "slug": "larp4"
        },
        {
          "symbol": "DIP2B",
          "ensemblId": "ENSG00000066084",
          "biotype": "protein_coding",
          "start": 50504962,
          "end": 50748657,
          "strand": "+",
          "slug": "dip2b"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-cellular-phenotype",
        "name": "Abnormal cellular phenotype",
        "systems": [],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-cellular-phenotype"
      },
      {
        "slug": "abnormal-erythrocyte-morphology",
        "name": "Abnormal erythrocyte morphology",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/abnormal-erythrocyte-morphology"
      },
      {
        "slug": "abnormal-erythroid-lineage-cell-morphology",
        "name": "Abnormal erythroid lineage cell morphology",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-erythroid-lineage-cell-morphology"
      },
      {
        "slug": "abnormal-proerythroblast-morphology",
        "name": "Abnormal proerythroblast morphology",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/abnormal-proerythroblast-morphology"
      },
      {
        "slug": "melena",
        "name": "Black feces",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/melena"
      },
      {
        "slug": "gingival-bleeding",
        "name": "Bleeding gums",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/gingival-bleeding"
      },
      {
        "slug": "post-partum-hemorrhage",
        "name": "Bleeding post-delivery",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/post-partum-hemorrhage"
      },
      {
        "slug": "elevated-circulating-iron-concentration",
        "name": "Elevated circulating iron concentration",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/elevated-circulating-iron-concentration"
      },
      {
        "slug": "fatigue",
        "name": "Fatigue",
        "systems": [
          "constitutional-symptom"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fatigue"
      },
      {
        "slug": "headache",
        "name": "Headache",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/headache"
      },
      {
        "slug": "hyperbilirubinemia",
        "name": "High blood bilirubin levels",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hyperbilirubinemia"
      },
      {
        "slug": "elevated-circulating-hepatic-transaminase-concentration",
        "name": "High liver enzymes",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/elevated-circulating-hepatic-transaminase-concentration"
      },
      {
        "slug": "increased-mean-corpuscular-volume",
        "name": "Increased mean corpuscular volume",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/increased-mean-corpuscular-volume"
      },
      {
        "slug": "increased-total-iron-binding-capacity",
        "name": "Increased total iron binding capacity",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/increased-total-iron-binding-capacity"
      },
      {
        "slug": "anemia",
        "name": "Low number of red blood cells or hemoglobin",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/anemia"
      },
      {
        "slug": "macrocytic-anemia",
        "name": "Macrocytic anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/macrocytic-anemia"
      },
      {
        "slug": "macrocytic-dyserythropoietic-anemia",
        "name": "Macrocytic dyserythropoietic anemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/macrocytic-dyserythropoietic-anemia"
      },
      {
        "slug": "oral-cavity-bleeding",
        "name": "Oral cavity bleeding",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/oral-cavity-bleeding"
      },
      {
        "slug": "pallor",
        "name": "Paleness",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pallor"
      },
      {
        "slug": "poikilocytosis",
        "name": "Poikilocytosis",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/poikilocytosis"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "very-rare",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "anisocytosis",
        "name": "Unequal size of red blood cells",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/anisocytosis"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}