{
  "url": "https://dantelabs.com/fr/genes/adra2a",
  "gene": {
    "slug": "adra2a",
    "symbol": "ADRA2A",
    "name": "adrenoceptor alpha 2A",
    "hgnc": "HGNC:281",
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    "location": "10q25.2",
    "locusType": "gene with protein product",
    "aliases": [
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      "ADRA2R"
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    "entrezId": 150,
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    "uniprot": [
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      "chrom": "10",
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      "strand": "+",
      "ensemblTranscript": "ENST00000280155.4",
      "refseqTranscript": "NM_000681.4",
      "ensemblProtein": "ENSP00000280155.2",
      "refseqProtein": "NP_000672.3",
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          "end": 111080907
        }
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        "end": 111079394
      }
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      "build": "GRCh37",
      "release": "87",
      "chrom": "10",
      "start": 112836790,
      "end": 112840658,
      "strand": "+"
    },
    "neighbourhood": {
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      "genes": [
        {
          "symbol": "SMC3",
          "ensemblId": "ENSG00000108055",
          "biotype": "protein_coding",
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          "end": 110606063,
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        {
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        {
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        {
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        {
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      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
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        "name": "Buffalo hump",
        "systems": [
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          "abnormality-of-the-musculoskeletal-system"
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dorsocervical-fat-pad"
      },
      {
        "slug": "acanthosis-nigricans",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/acanthosis-nigricans"
      },
      {
        "slug": "diabetes-mellitus",
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        "url": "https://dantelabs.com/traits/diabetes-mellitus"
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      {
        "slug": "elevated-circulating-creatine-kinase-activity",
        "name": "Elevated blood creatine phosphokinase",
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/elevated-circulating-creatine-kinase-activity"
      },
      {
        "slug": "hepatomegaly",
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hepatomegaly"
      },
      {
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        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/gout"
      },
      {
        "slug": "hypertension",
        "name": "High blood pressure",
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        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hypertension"
      },
      {
        "slug": "hyperglycemia",
        "name": "High blood sugar",
        "systems": [
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        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hyperglycemia"
      },
      {
        "slug": "hyperuricemia",
        "name": "High blood uric acid level",
        "systems": [
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        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hyperuricemia"
      },
      {
        "slug": "lipodystrophy",
        "name": "Inability to make and keep healthy fat tissue",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/lipodystrophy"
      },
      {
        "slug": "hypertriglyceridemia",
        "name": "Increased plasma triglycerides",
        "systems": [
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hypertriglyceridemia"
      },
      {
        "slug": "obstructive-sleep-apnea",
        "name": "Obstructive sleep apnea",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/obstructive-sleep-apnea"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}