{
  "url": "https://dantelabs.com/traits/short-5th-toe",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "short-5th-toe",
    "id": "HP:0011917",
    "name": "Short little toe",
    "label": "Short 5th toe",
    "definition": "Underdevelopment (hypoplasia) of the fifth toe.",
    "synonyms": [
      "Short pinkie toe",
      "Short pinky toe",
      "Short fifth toe"
    ],
    "systems": [
      {
        "slug": "abnormality-of-limbs",
        "name": "Abnormality of limbs",
        "url": "https://dantelabs.com/traits/abnormality-of-limbs"
      },
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "short-toe",
        "name": "Short toe",
        "url": "https://dantelabs.com/traits/short-toe"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ep300",
        "symbol": "EP300",
        "hgnc": "HGNC:3373",
        "name": "EP300 lysine acetyltransferase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ep300"
      },
      {
        "slug": "cox4i1",
        "symbol": "COX4I1",
        "hgnc": "HGNC:2265",
        "name": "cytochrome c oxidase subunit 4I1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cox4i1"
      },
      {
        "slug": "dyrk1a",
        "symbol": "DYRK1A",
        "hgnc": "HGNC:3091",
        "name": "dual specificity tyrosine phosphorylation regulated kinase 1A",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dyrk1a"
      },
      {
        "slug": "rbpj",
        "symbol": "RBPJ",
        "hgnc": "HGNC:5724",
        "name": "recombination signal binding protein for immunoglobulin kappa J region",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbpj"
      },
      {
        "slug": "tbx3",
        "symbol": "TBX3",
        "hgnc": "HGNC:11602",
        "name": "T-box transcription factor 3",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx3"
      }
    ]
  }
}