{
  "url": "https://dantelabs.com/traits/severe-temper-tantrums",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "severe-temper-tantrums",
    "id": "HP:0025162",
    "name": "Severe temper tantrums",
    "definition": "Temper tantrums, which occur with more severe symptomatology compared to a temper tantrum that occurs as a part of normal developmental process.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-temper-tantrums",
        "name": "Abnormal temper tantrums",
        "url": "https://dantelabs.com/traits/abnormal-temper-tantrums"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "rsrc1",
        "symbol": "RSRC1",
        "hgnc": "HGNC:24152",
        "name": "arginine and serine rich coiled-coil 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rsrc1"
      },
      {
        "slug": "wars2",
        "symbol": "WARS2",
        "hgnc": "HGNC:12730",
        "name": "tryptophanyl tRNA synthetase 2, mitochondrial",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wars2"
      },
      {
        "slug": "gnai1",
        "symbol": "GNAI1",
        "hgnc": "HGNC:4384",
        "name": "G protein subunit alpha i1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnai1"
      },
      {
        "slug": "scn8a",
        "symbol": "SCN8A",
        "hgnc": "HGNC:10596",
        "name": "sodium voltage-gated channel alpha subunit 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scn8a"
      },
      {
        "slug": "dpf2",
        "symbol": "DPF2",
        "hgnc": "HGNC:9964",
        "name": "double PHD fingers 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dpf2"
      },
      {
        "slug": "taco1",
        "symbol": "TACO1",
        "hgnc": "HGNC:24316",
        "name": "translational activator of cytochrome c oxidase I",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taco1"
      }
    ]
  }
}