{
  "url": "https://dantelabs.com/traits/recurrent-gastroenteritis",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "recurrent-gastroenteritis",
    "id": "HP:0031123",
    "name": "Recurrent gastroenteritis",
    "definition": "Increased susceptibility to gastroenteritis, an infectious inflammationof the stomach and small intestines manifested by signs and symptoms such as diarheas and abdominal pain, as manifested by recurrent episodes of gastroenteritis.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "recurrent-infection-of-the-gastrointestinal-tract",
        "name": "Recurrent infection of the gastrointestinal tract",
        "url": "https://dantelabs.com/traits/recurrent-infection-of-the-gastrointestinal-tract"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "adam17",
        "symbol": "ADAM17",
        "hgnc": "HGNC:195",
        "name": "ADAM metallopeptidase domain 17",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adam17"
      },
      {
        "slug": "dock11",
        "symbol": "DOCK11",
        "hgnc": "HGNC:23483",
        "name": "dedicator of cytokinesis 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dock11"
      },
      {
        "slug": "man2b1",
        "symbol": "MAN2B1",
        "hgnc": "HGNC:6826",
        "name": "mannosidase alpha class 2B member 1",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/man2b1"
      },
      {
        "slug": "sp110",
        "symbol": "SP110",
        "hgnc": "HGNC:5401",
        "name": "SP110 nuclear body protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sp110"
      },
      {
        "slug": "spink5",
        "symbol": "SPINK5",
        "hgnc": "HGNC:15464",
        "name": "serine peptidase inhibitor Kazal type 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/spink5"
      },
      {
        "slug": "vps33a",
        "symbol": "VPS33A",
        "hgnc": "HGNC:18179",
        "name": "VPS33A core subunit of CORVET and HOPS complexes",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps33a"
      },
      {
        "slug": "adat3",
        "symbol": "ADAT3",
        "hgnc": "HGNC:25151",
        "name": "adenosine deaminase tRNA specific 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adat3"
      },
      {
        "slug": "blm",
        "symbol": "BLM",
        "hgnc": "HGNC:1058",
        "name": "BLM RecQ like helicase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/blm"
      },
      {
        "slug": "dclre1c",
        "symbol": "DCLRE1C",
        "hgnc": "HGNC:17642",
        "name": "DNA cross-link repair 1C",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dclre1c"
      },
      {
        "slug": "foxp3",
        "symbol": "FOXP3",
        "hgnc": "HGNC:6106",
        "name": "forkhead box P3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/foxp3"
      },
      {
        "slug": "slc35c1",
        "symbol": "SLC35C1",
        "hgnc": "HGNC:20197",
        "name": "solute carrier family 35 member C1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc35c1"
      },
      {
        "slug": "cd3e",
        "symbol": "CD3E",
        "hgnc": "HGNC:1674",
        "name": "CD3 epsilon subunit of T-cell receptor complex",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd3e"
      },
      {
        "slug": "cd3g",
        "symbol": "CD3G",
        "hgnc": "HGNC:1675",
        "name": "CD3 gamma subunit of T-cell receptor complex",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd3g"
      },
      {
        "slug": "irf9",
        "symbol": "IRF9",
        "hgnc": "HGNC:6131",
        "name": "interferon regulatory factor 9",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf9"
      }
    ]
  }
}