{
  "url": "https://dantelabs.com/traits/pseudoarthrosis",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "pseudoarthrosis",
    "id": "HP:0005864",
    "name": "Pseudoarthrosis",
    "definition": "A pathologic entity characterized by a developmental defect in a long bone leading to bending and pathologic fracture, with inability to form a normal bony callus with subsequent fibrous nonunion, leading to the pseudarthrosis (or \"false joint\").",
    "synonyms": [
      "Pseudoarthroses"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-long-bone-morphology",
        "name": "Abnormal shape of long bone",
        "url": "https://dantelabs.com/traits/abnormal-long-bone-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "congenital-pseudoarthrosis-of-the-clavicle",
        "name": "Congenital pseudoarthrosis of the clavicle",
        "genes": 6,
        "url": "https://dantelabs.com/traits/congenital-pseudoarthrosis-of-the-clavicle"
      },
      {
        "slug": "tibial-pseudarthrosis",
        "name": "Tibial pseudarthrosis",
        "genes": 1,
        "url": "https://dantelabs.com/traits/tibial-pseudarthrosis"
      }
    ],
    "genes": [
      {
        "slug": "ccdc134",
        "symbol": "CCDC134",
        "hgnc": "HGNC:26185",
        "name": "coiled-coil domain containing 134",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc134"
      },
      {
        "slug": "myf5",
        "symbol": "MYF5",
        "hgnc": "HGNC:7565",
        "name": "myogenic factor 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myf5"
      },
      {
        "slug": "fgfr1",
        "symbol": "FGFR1",
        "hgnc": "HGNC:3688",
        "name": "fibroblast growth factor receptor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fgfr1"
      },
      {
        "slug": "met",
        "symbol": "MET",
        "hgnc": "HGNC:7029",
        "name": "MET proto-oncogene, receptor tyrosine kinase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/met"
      }
    ]
  }
}