{
  "url": "https://dantelabs.com/traits/open-operculum",
  "trait": {
    "bundleId": "2026.10.16-c6eea6bf",
    "release": "2026-09-01",
    "slug": "open-operculum",
    "id": "HP:0100954",
    "name": "Open operculum",
    "definition": "Underdevelopment of the operculum.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-cerebral-cortex-morphology",
        "name": "Abnormal cerebral cortex morphology",
        "url": "https://dantelabs.com/traits/abnormal-cerebral-cortex-morphology"
      },
      {
        "slug": "cerebral-hypoplasia",
        "name": "Small cerebrum",
        "url": "https://dantelabs.com/traits/cerebral-hypoplasia"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "c2cd3",
        "symbol": "C2CD3",
        "hgnc": "HGNC:24564",
        "name": "C2 domain containing 3 centriole elongation regulator",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c2cd3"
      },
      {
        "slug": "gcdh",
        "symbol": "GCDH",
        "hgnc": "HGNC:4189",
        "name": "glutaryl-CoA dehydrogenase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gcdh"
      },
      {
        "slug": "cnnm2",
        "symbol": "CNNM2",
        "hgnc": "HGNC:103",
        "name": "cyclin and CBS domain divalent metal cation transport mediator 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnnm2"
      },
      {
        "slug": "cspp1",
        "symbol": "CSPP1",
        "hgnc": "HGNC:26193",
        "name": "centrosome and spindle pole associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cspp1"
      },
      {
        "slug": "kiaa0586",
        "symbol": "KIAA0586",
        "hgnc": "HGNC:19960",
        "name": "KIAA0586",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa0586"
      },
      {
        "slug": "fh",
        "symbol": "FH",
        "hgnc": "HGNC:3700",
        "name": "fumarate hydratase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fh"
      }
    ]
  }
}