{
  "url": "https://dantelabs.com/traits/ewing-sarcoma",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "ewing-sarcoma",
    "id": "HP:0012254",
    "name": "Ewing sarcoma",
    "definition": "A malignant tumor of the bone which always arises in the medullary tissue, occurring more often in cylindrical bones.",
    "synonyms": [
      "Ewing's sarcoma"
    ],
    "systems": [
      {
        "slug": "neoplasm",
        "name": "Abnormal tissue mass",
        "url": "https://dantelabs.com/traits/neoplasm"
      }
    ],
    "broader": [
      {
        "slug": "sarcoma",
        "name": "Cancer of connective tissue",
        "url": "https://dantelabs.com/traits/sarcoma"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "brd4",
        "symbol": "BRD4",
        "hgnc": "HGNC:13575",
        "name": "bromodomain containing 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brd4"
      },
      {
        "slug": "nutm1",
        "symbol": "NUTM1",
        "hgnc": "HGNC:29919",
        "name": "NUT midline carcinoma family member 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nutm1"
      },
      {
        "slug": "ewsr1",
        "symbol": "EWSR1",
        "hgnc": "HGNC:3508",
        "name": "EWS RNA binding protein 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ewsr1"
      },
      {
        "slug": "rb1",
        "symbol": "RB1",
        "hgnc": "HGNC:9884",
        "name": "RB transcriptional corepressor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rb1"
      }
    ]
  }
}