{
  "url": "https://dantelabs.com/traits/dilated-third-ventricle",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "dilated-third-ventricle",
    "id": "HP:0007082",
    "name": "Dilated third ventricle",
    "definition": "An increase in size of the third ventricle.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-nervous-system",
        "name": "Abnormality of the nervous system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-nervous-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-third-ventricle-morphology",
        "name": "Abnormal third ventricle morphology",
        "url": "https://dantelabs.com/traits/abnormal-third-ventricle-morphology"
      },
      {
        "slug": "ventriculomegaly",
        "name": "Ventriculomegaly",
        "url": "https://dantelabs.com/traits/ventriculomegaly"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "asns",
        "symbol": "ASNS",
        "hgnc": "HGNC:753",
        "name": "asparagine synthetase (glutamine-hydrolyzing)",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asns"
      },
      {
        "slug": "esam",
        "symbol": "ESAM",
        "hgnc": "HGNC:17474",
        "name": "endothelial cell adhesion molecule",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/esam"
      },
      {
        "slug": "rnu6atac",
        "symbol": "RNU6ATAC",
        "hgnc": "HGNC:34017",
        "name": "RNA, U6atac small nuclear",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6atac"
      },
      {
        "slug": "c2cd3",
        "symbol": "C2CD3",
        "hgnc": "HGNC:24564",
        "name": "C2 domain containing 3 centriole elongation regulator",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/c2cd3"
      },
      {
        "slug": "kidins220",
        "symbol": "KIDINS220",
        "hgnc": "HGNC:29508",
        "name": "kinase D interacting substrate 220",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kidins220"
      },
      {
        "slug": "large1",
        "symbol": "LARGE1",
        "hgnc": "HGNC:6511",
        "name": "LARGE xylosyl- and glucuronyltransferase 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/large1"
      },
      {
        "slug": "usp7",
        "symbol": "USP7",
        "hgnc": "HGNC:12630",
        "name": "ubiquitin specific peptidase 7",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp7"
      },
      {
        "slug": "atp6ap2",
        "symbol": "ATP6AP2",
        "hgnc": "HGNC:18305",
        "name": "ATPase H+ transporting accessory protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atp6ap2"
      },
      {
        "slug": "cspp1",
        "symbol": "CSPP1",
        "hgnc": "HGNC:26193",
        "name": "centrosome and spindle pole associated protein 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cspp1"
      },
      {
        "slug": "dnmt1",
        "symbol": "DNMT1",
        "hgnc": "HGNC:2976",
        "name": "DNA methyltransferase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnmt1"
      },
      {
        "slug": "eif2b5",
        "symbol": "EIF2B5",
        "hgnc": "HGNC:3261",
        "name": "eukaryotic translation initiation factor 2B subunit epsilon",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eif2b5"
      },
      {
        "slug": "kcnn2",
        "symbol": "KCNN2",
        "hgnc": "HGNC:6291",
        "name": "potassium calcium-activated channel subfamily N member 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kcnn2"
      },
      {
        "slug": "kiaa0586",
        "symbol": "KIAA0586",
        "hgnc": "HGNC:19960",
        "name": "KIAA0586",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa0586"
      },
      {
        "slug": "med25",
        "symbol": "MED25",
        "hgnc": "HGNC:28845",
        "name": "mediator complex subunit 25",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/med25"
      },
      {
        "slug": "odc1",
        "symbol": "ODC1",
        "hgnc": "HGNC:8109",
        "name": "ornithine decarboxylase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/odc1"
      },
      {
        "slug": "taok1",
        "symbol": "TAOK1",
        "hgnc": "HGNC:29259",
        "name": "TAO kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taok1"
      },
      {
        "slug": "ttc5",
        "symbol": "TTC5",
        "hgnc": "HGNC:19274",
        "name": "tetratricopeptide repeat domain 5",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc5"
      }
    ]
  }
}