{
  "url": "https://dantelabs.com/traits/capillary-leak",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "capillary-leak",
    "id": "HP:0030005",
    "name": "Capillary leak",
    "definition": "An acute phenomenon characterized by hypotension and anasarca due to the loss of plasma volume into peripheral tissues, with evidence of decreased plasma volume (hemoconcentration) and protein loss from the intravascular space (hypoalbuminemia) during acute episodes.",
    "synonyms": [
      "Increased capillary permeability"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-capillary-physiology",
        "name": "Abnormal capillary physiology",
        "url": "https://dantelabs.com/traits/abnormal-capillary-physiology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "lck",
        "symbol": "LCK",
        "hgnc": "HGNC:6524",
        "name": "LCK proto-oncogene, Src family tyrosine kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lck"
      },
      {
        "slug": "fshr",
        "symbol": "FSHR",
        "hgnc": "HGNC:3969",
        "name": "follicle stimulating hormone receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fshr"
      }
    ]
  }
}