{
  "url": "https://dantelabs.com/traits/abnormal-upper-lip-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-upper-lip-morphology",
    "id": "HP:0000177",
    "name": "Abnormality of upper lip",
    "label": "Abnormal upper lip morphology",
    "definition": "An abnormality of the upper lip.",
    "synonyms": [
      "Anomaly of the upper lip",
      "Deformity of the upper lip",
      "Malformation of the upper lip"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-lip-morphology",
        "name": "Abnormal lip",
        "url": "https://dantelabs.com/traits/abnormal-lip-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "cleft-upper-lip",
        "name": "Cleft upper lip",
        "genes": 103,
        "url": "https://dantelabs.com/traits/cleft-upper-lip"
      },
      {
        "slug": "abnormality-of-the-philtrum",
        "name": "Abnormality of the philtrum",
        "genes": 13,
        "url": "https://dantelabs.com/traits/abnormality-of-the-philtrum"
      },
      {
        "slug": "short-upper-lip",
        "name": "Short upper lip",
        "genes": 13,
        "url": "https://dantelabs.com/traits/short-upper-lip"
      },
      {
        "slug": "long-upper-lip",
        "name": "Long upper lip",
        "genes": 8,
        "url": "https://dantelabs.com/traits/long-upper-lip"
      },
      {
        "slug": "abnormality-of-upper-lip-vermillion",
        "name": "Abnormality of the red part of the upper lip",
        "genes": 3,
        "url": "https://dantelabs.com/traits/abnormality-of-upper-lip-vermillion"
      },
      {
        "slug": "upper-lip-pit",
        "name": "Upper lip pit",
        "genes": 1,
        "url": "https://dantelabs.com/traits/upper-lip-pit"
      }
    ],
    "genes": [
      {
        "slug": "dis3l2",
        "symbol": "DIS3L2",
        "hgnc": "HGNC:28648",
        "name": "DIS3 like 3'-5' exoribonuclease 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dis3l2"
      },
      {
        "slug": "hic1",
        "symbol": "HIC1",
        "hgnc": "HGNC:4909",
        "name": "HIC ZBTB transcriptional repressor 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hic1"
      },
      {
        "slug": "pafah1b1",
        "symbol": "PAFAH1B1",
        "hgnc": "HGNC:8574",
        "name": "platelet activating factor acetylhydrolase 1b regulatory subunit 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pafah1b1"
      },
      {
        "slug": "ywhae",
        "symbol": "YWHAE",
        "hgnc": "HGNC:12851",
        "name": "tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ywhae"
      },
      {
        "slug": "znhit3",
        "symbol": "ZNHIT3",
        "hgnc": "HGNC:12309",
        "name": "zinc finger HIT-type containing 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znhit3"
      },
      {
        "slug": "ube3b",
        "symbol": "UBE3B",
        "hgnc": "HGNC:13478",
        "name": "ubiquitin protein ligase E3B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ube3b"
      }
    ]
  }
}