{
  "url": "https://dantelabs.com/traits/abnormal-thymus-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-thymus-morphology",
    "id": "HP:0000777",
    "name": "Abnormality of the thymus",
    "label": "Abnormal thymus morphology",
    "definition": "Abnormality of the thymus, an organ located in the upper anterior portion of the chest cavity just behind the sternum and whose main function is to provide an environment for T lymphocyte maturation.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-cardiovascular-system",
        "name": "Abnormality of the cardiovascular system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-cardiovascular-system"
      },
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      },
      {
        "slug": "abnormality-of-the-lymphatic-system",
        "name": "Abnormality of the lymphatic system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-lymphatic-system"
      }
    ],
    "narrower": [
      {
        "slug": "thymus-hyperplasia",
        "name": "Enlarged thymus",
        "genes": 6,
        "url": "https://dantelabs.com/traits/thymus-hyperplasia"
      },
      {
        "slug": "aplasia-hypoplasia-of-the-thymus",
        "name": "Absent/small thymus",
        "genes": 5,
        "url": "https://dantelabs.com/traits/aplasia-hypoplasia-of-the-thymus"
      },
      {
        "slug": "ectopic-thymus-tissue",
        "name": "Abnormal thymus position",
        "genes": 1,
        "url": "https://dantelabs.com/traits/ectopic-thymus-tissue"
      },
      {
        "slug": "neoplasm-of-the-thymus",
        "name": "Neoplasm of the thymus",
        "genes": 1,
        "url": "https://dantelabs.com/traits/neoplasm-of-the-thymus"
      },
      {
        "slug": "thymic-hormone-decreased",
        "name": "Thymic hormone decreased",
        "genes": 1,
        "url": "https://dantelabs.com/traits/thymic-hormone-decreased"
      }
    ],
    "genes": [
      {
        "slug": "epg5",
        "symbol": "EPG5",
        "hgnc": "HGNC:29331",
        "name": "ectopic P-granules 5 autophagy tethering factor",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epg5"
      },
      {
        "slug": "fras1",
        "symbol": "FRAS1",
        "hgnc": "HGNC:19185",
        "name": "Fraser extracellular matrix complex subunit 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fras1"
      },
      {
        "slug": "tbx1",
        "symbol": "TBX1",
        "hgnc": "HGNC:11592",
        "name": "T-box transcription factor 1",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbx1"
      }
    ]
  }
}