{
  "url": "https://dantelabs.com/fi/genes/xpnpep2",
  "gene": {
    "slug": "xpnpep2",
    "symbol": "XPNPEP2",
    "name": "X-prolyl aminopeptidase 2",
    "hgnc": "HGNC:12823",
    "summary": null,
    "location": "Xq26.1",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000122121",
    "entrezId": 7512,
    "omim": [
      "300145"
    ],
    "uniprot": [
      "O43895"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "X",
      "start": 129738979,
      "end": 129769536,
      "strand": "+",
      "ensemblTranscript": "ENST00000371106.4",
      "refseqTranscript": "NM_003399.6",
      "ensemblProtein": "ENSP00000360147.3",
      "refseqProtein": "NP_003390.4",
      "exons": [
        {
          "start": 129738979,
          "end": 129739262
        },
        {
          "start": 129742108,
          "end": 129742181
        },
        {
          "start": 129743961,
          "end": 129744071
        },
        {
          "start": 129745203,
          "end": 129745266
        },
        {
          "start": 129746236,
          "end": 129746340
        },
        {
          "start": 129746595,
          "end": 129746681
        },
        {
          "start": 129747607,
          "end": 129747753
        },
        {
          "start": 129750468,
          "end": 129750569
        },
        {
          "start": 129751745,
          "end": 129751826
        },
        {
          "start": 129752150,
          "end": 129752345
        },
        {
          "start": 129753159,
          "end": 129753248
        },
        {
          "start": 129754472,
          "end": 129754581
        },
        {
          "start": 129755294,
          "end": 129755371
        },
        {
          "start": 129756484,
          "end": 129756555
        },
        {
          "start": 129759180,
          "end": 129759240
        },
        {
          "start": 129760512,
          "end": 129760581
        },
        {
          "start": 129761172,
          "end": 129761276
        },
        {
          "start": 129762006,
          "end": 129762065
        },
        {
          "start": 129762694,
          "end": 129762770
        },
        {
          "start": 129767603,
          "end": 129767692
        },
        {
          "start": 129768291,
          "end": 129769536
        }
      ],
      "cds": {
        "start": 129739214,
        "end": 129768485
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "X",
      "start": 128872950,
      "end": 128903514,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 129254258,
      "end": 130254257,
      "genes": [
        {
          "symbol": "SMARCA1",
          "ensemblId": "ENSG00000102038",
          "biotype": "protein_coding",
          "start": 129446402,
          "end": 129523947,
          "strand": "-",
          "slug": "smarca1"
        },
        {
          "symbol": "OCRL",
          "ensemblId": "ENSG00000122126",
          "biotype": "protein_coding",
          "start": 129539849,
          "end": 129592772,
          "strand": "+",
          "slug": "ocrl"
        },
        {
          "symbol": "APLN",
          "ensemblId": "ENSG00000171388",
          "biotype": "protein_coding",
          "start": 129645259,
          "end": 129654965,
          "strand": "-",
          "slug": "apln"
        },
        {
          "symbol": "SASH3",
          "ensemblId": "ENSG00000122122",
          "biotype": "protein_coding",
          "start": 129779901,
          "end": 129795201,
          "strand": "+",
          "slug": "sash3"
        },
        {
          "symbol": "ZDHHC9",
          "ensemblId": "ENSG00000188706",
          "biotype": "protein_coding",
          "start": 129797030,
          "end": 129844215,
          "strand": "-",
          "slug": "zdhhc9"
        },
        {
          "symbol": "UTP14A",
          "ensemblId": "ENSG00000156697",
          "biotype": "protein_coding",
          "start": 129906114,
          "end": 129929957,
          "strand": "+",
          "slug": "utp14a"
        },
        {
          "symbol": "BCORL1",
          "ensemblId": "ENSG00000085185",
          "biotype": "protein_coding",
          "start": 129981107,
          "end": 130058071,
          "strand": "+",
          "slug": "bcorl1"
        },
        {
          "symbol": "ELF4",
          "ensemblId": "ENSG00000102034",
          "biotype": "protein_coding",
          "start": 130063955,
          "end": 130110951,
          "strand": "-",
          "slug": "elf4"
        },
        {
          "symbol": "AIFM1",
          "ensemblId": "ENSG00000156709",
          "biotype": "protein_coding",
          "start": 130124666,
          "end": 130165884,
          "strand": "-",
          "slug": "aifm1"
        },
        {
          "symbol": "RAB33A",
          "ensemblId": "ENSG00000134594",
          "biotype": "protein_coding",
          "start": 130171720,
          "end": 130184874,
          "strand": "+",
          "slug": "rab33a"
        },
        {
          "symbol": "ZNF280C",
          "ensemblId": "ENSG00000056277",
          "biotype": "protein_coding",
          "start": 130202699,
          "end": 130268923,
          "strand": "-",
          "slug": "znf280c"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "abnormal-capillary-physiology",
        "name": "Abnormal capillary physiology",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/abnormal-capillary-physiology"
      },
      {
        "slug": "angioedema",
        "name": "Angioedema",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/angioedema"
      },
      {
        "slug": "respiratory-distress",
        "name": "Breathing difficulties",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/respiratory-distress"
      },
      {
        "slug": "facial-edema",
        "name": "Facial puffiness",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/facial-edema"
      },
      {
        "slug": "palpebral-edema",
        "name": "Fullness of eyelids",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/palpebral-edema"
      },
      {
        "slug": "urticaria",
        "name": "Hives",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/urticaria"
      },
      {
        "slug": "pruritus",
        "name": "Itching",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "url": "https://dantelabs.com/traits/pruritus"
      },
      {
        "slug": "laryngeal-edema",
        "name": "Laryngeal edema",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/laryngeal-edema"
      },
      {
        "slug": "erythema",
        "name": "Redness of skin or mucous membrane",
        "systems": [
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/erythema"
      },
      {
        "slug": "swollen-lip",
        "name": "Swollen lip",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/swollen-lip"
      },
      {
        "slug": "pharyngeal-edema",
        "name": "Throat swelling",
        "systems": [
          "abnormality-of-metabolism-homeostasis",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pharyngeal-edema"
      },
      {
        "slug": "tongue-edema",
        "name": "Tongue edema",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-metabolism-homeostasis"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/tongue-edema"
      },
      {
        "slug": "upper-airway-obstruction",
        "name": "Upper airway obstruction",
        "systems": [
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/upper-airway-obstruction"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}