{
  "url": "https://dantelabs.com/fi/genes/wbp11",
  "gene": {
    "slug": "wbp11",
    "symbol": "WBP11",
    "name": "WW domain binding protein 11",
    "hgnc": "HGNC:16461",
    "summary": null,
    "location": "12p12.3",
    "locusType": "gene with protein product",
    "aliases": [
      "NPWBP",
      "SIPP1",
      "PPP1R165",
      "BUG13"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000084463",
    "entrezId": 51729,
    "omim": [
      "618083"
    ],
    "uniprot": [
      "Q9Y2W2"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "12",
      "start": 14784582,
      "end": 14803478,
      "strand": "-",
      "ensemblTranscript": "ENST00000261167.7",
      "refseqTranscript": "NM_016312.3",
      "ensemblProtein": "ENSP00000261167.2",
      "refseqProtein": "NP_057396.1",
      "exons": [
        {
          "start": 14784582,
          "end": 14787498
        },
        {
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      ],
      "cds": {
        "start": 14787065,
        "end": 14801383
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "12",
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      "end": 14956474,
      "strand": "-"
    },
    "neighbourhood": {
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      "end": 15294029,
      "genes": [
        {
          "symbol": "ATF7IP",
          "ensemblId": "ENSG00000171681",
          "biotype": "protein_coding",
          "start": 14365439,
          "end": 14502931,
          "strand": "+",
          "slug": "atf7ip"
        },
        {
          "symbol": "PLBD1",
          "ensemblId": "ENSG00000121316",
          "biotype": "protein_coding",
          "start": 14503660,
          "end": 14567928,
          "strand": "-",
          "slug": "plbd1"
        },
        {
          "symbol": "GUCY2C",
          "ensemblId": "ENSG00000070019",
          "biotype": "protein_coding",
          "start": 14612632,
          "end": 14696652,
          "strand": "-",
          "slug": "gucy2c"
        },
        {
          "symbol": "H4C16",
          "ensemblId": "ENSG00000197837",
          "biotype": "protein_coding",
          "start": 14767999,
          "end": 14771131,
          "strand": "-",
          "slug": "h4c16"
        },
        {
          "symbol": "H2AJ",
          "ensemblId": "ENSG00000246705",
          "biotype": "protein_coding",
          "start": 14774405,
          "end": 14778002,
          "strand": "+",
          "slug": "h2aj"
        },
        {
          "symbol": "C12orf60",
          "ensemblId": "ENSG00000182993",
          "biotype": "protein_coding",
          "start": 14802864,
          "end": 14906586,
          "strand": "+",
          "slug": "c12orf60"
        },
        {
          "symbol": "SMCO3",
          "ensemblId": "ENSG00000179256",
          "biotype": "protein_coding",
          "start": 14804065,
          "end": 14814189,
          "strand": "-",
          "slug": "smco3"
        },
        {
          "symbol": "ART4",
          "ensemblId": "ENSG00000111339",
          "biotype": "protein_coding",
          "start": 14822378,
          "end": 14843630,
          "strand": "-",
          "slug": "art4"
        },
        {
          "symbol": "MGP",
          "ensemblId": "ENSG00000111341",
          "biotype": "protein_coding",
          "start": 14879368,
          "end": 14905245,
          "strand": "-",
          "slug": "mgp"
        },
        {
          "symbol": "ERP27",
          "ensemblId": "ENSG00000139055",
          "biotype": "protein_coding",
          "start": 14912600,
          "end": 14938557,
          "strand": "-",
          "slug": "erp27"
        },
        {
          "symbol": "ARHGDIB",
          "ensemblId": "ENSG00000111348",
          "biotype": "protein_coding",
          "start": 14942009,
          "end": 14961985,
          "strand": "-",
          "slug": "arhgdib"
        },
        {
          "symbol": "PDE6H",
          "ensemblId": "ENSG00000139053",
          "biotype": "protein_coding",
          "start": 14949827,
          "end": 14982699,
          "strand": "+",
          "slug": "pde6h"
        },
        {
          "symbol": "RERG",
          "ensemblId": "ENSG00000134533",
          "biotype": "protein_coding",
          "start": 15107783,
          "end": 15390485,
          "strand": "-",
          "slug": "rerg"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "tracheoesophageal-fistula",
        "name": "Abnormal connection between trachea and esophagus",
        "systems": [
          "abnormality-of-the-digestive-system",
          "abnormality-of-the-respiratory-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/tracheoesophageal-fistula"
      },
      {
        "slug": "microcephaly",
        "name": "Abnormally small head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system",
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/microcephaly"
      },
      {
        "slug": "duodenal-atresia",
        "name": "Absence or narrowing of first part of small bowel",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/duodenal-atresia"
      },
      {
        "slug": "renal-agenesis",
        "name": "Absent kidney",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/renal-agenesis"
      },
      {
        "slug": "unilateral-renal-agenesis",
        "name": "Absent kidney on one side",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/unilateral-renal-agenesis"
      },
      {
        "slug": "plagiocephaly",
        "name": "Asymmetry of the posterior head",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/plagiocephaly"
      },
      {
        "slug": "attention-deficit-hyperactivity-disorder",
        "name": "Attention deficit",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/attention-deficit-hyperactivity-disorder"
      },
      {
        "slug": "esophageal-atresia",
        "name": "Birth defect in which part of esophagus did not develop",
        "systems": [
          "abnormality-of-the-digestive-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/esophageal-atresia"
      },
      {
        "slug": "cafe-au-lait-spot",
        "name": "Birthmark",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/cafe-au-lait-spot"
      },
      {
        "slug": "choanal-atresia",
        "name": "Blockage of the rear opening of the nasal cavity",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/choanal-atresia"
      },
      {
        "slug": "broad-forehead",
        "name": "Broad forehead",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/broad-forehead"
      },
      {
        "slug": "butterfly-vertebrae",
        "name": "Butterfly vertebrae",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/butterfly-vertebrae"
      },
      {
        "slug": "hypertrichosis",
        "name": "Excessive hair growth",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/hypertrichosis"
      },
      {
        "slug": "pectus-excavatum",
        "name": "Funnel chest",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/pectus-excavatum"
      },
      {
        "slug": "fused-cervical-vertebrae",
        "name": "Fused neck",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/fused-cervical-vertebrae"
      },
      {
        "slug": "global-developmental-delay",
        "name": "Global developmental delay",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/global-developmental-delay"
      },
      {
        "slug": "sprengel-anomaly",
        "name": "High shoulder blade",
        "systems": [
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/sprengel-anomaly"
      },
      {
        "slug": "low-posterior-hairline",
        "name": "Low hairline at back of neck",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/low-posterior-hairline"
      },
      {
        "slug": "low-set-ears",
        "name": "Low-set ears",
        "systems": [
          "abnormality-of-the-ear"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/low-set-ears"
      },
      {
        "slug": "muscular-ventricular-septal-defect",
        "name": "Muscular ventricular septal defect",
        "systems": [
          "abnormality-of-the-cardiovascular-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/muscular-ventricular-septal-defect"
      },
      {
        "slug": "preauricular-pit",
        "name": "Pit in front of the ear",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/preauricular-pit"
      },
      {
        "slug": "retrognathia",
        "name": "Receding chin",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-musculoskeletal-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/retrognathia"
      },
      {
        "slug": "short-stature",
        "name": "Short stature",
        "systems": [
          "growth-abnormality"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/short-stature"
      },
      {
        "slug": "preauricular-skin-tag",
        "name": "Skin tag in front of the ear",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-integument"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/preauricular-skin-tag"
      },
      {
        "slug": "spina-bifida-occulta",
        "name": "Spina bifida occulta",
        "systems": [
          "abnormality-of-the-nervous-system"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/spina-bifida-occulta"
      },
      {
        "slug": "submucous-cleft-hard-palate",
        "name": "Submucous cleft hard palate",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/submucous-cleft-hard-palate"
      },
      {
        "slug": "webbed-neck",
        "name": "Webbed neck",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/webbed-neck"
      },
      {
        "slug": "wide-nose",
        "name": "Wide nose",
        "systems": [
          "abnormality-of-head-or-neck"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/wide-nose"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}