{
  "url": "https://dantelabs.com/fi/genes/picalm",
  "gene": {
    "slug": "picalm",
    "symbol": "PICALM",
    "name": "phosphatidylinositol binding clathrin assembly protein",
    "hgnc": "HGNC:15514",
    "summary": null,
    "location": "11q14.2",
    "locusType": "gene with protein product",
    "aliases": [
      "CALM",
      "CLTH"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000073921",
    "entrezId": 8301,
    "omim": [
      "603025"
    ],
    "uniprot": [
      "Q13492"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "11",
      "start": 85957175,
      "end": 86069084,
      "strand": "-",
      "ensemblTranscript": "ENST00000393346.8",
      "refseqTranscript": "NM_007166.4",
      "ensemblProtein": "ENSP00000377015.3",
      "refseqProtein": "NP_009097.2",
      "exons": [
        {
          "start": 85957175,
          "end": 85959060
        },
        {
          "start": 85974708,
          "end": 85974812
        },
        {
          "start": 85976623,
          "end": 85976682
        },
        {
          "start": 85981129,
          "end": 85981228
        },
        {
          "start": 85981745,
          "end": 85981775
        },
        {
          "start": 85981872,
          "end": 85982003
        },
        {
          "start": 85983866,
          "end": 85983973
        },
        {
          "start": 85990250,
          "end": 85990399
        },
        {
          "start": 85996826,
          "end": 85996929
        },
        {
          "start": 86000643,
          "end": 86000779
        },
        {
          "start": 86001035,
          "end": 86001158
        },
        {
          "start": 86003366,
          "end": 86003451
        },
        {
          "start": 86007542,
          "end": 86007583
        },
        {
          "start": 86011030,
          "end": 86011136
        },
        {
          "start": 86012281,
          "end": 86012392
        },
        {
          "start": 86014870,
          "end": 86014963
        },
        {
          "start": 86022367,
          "end": 86022469
        },
        {
          "start": 86026292,
          "end": 86026367
        },
        {
          "start": 86031469,
          "end": 86031611
        },
        {
          "start": 86068651,
          "end": 86069084
        }
      ],
      "cds": {
        "start": 85959046,
        "end": 86068780
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "11",
      "start": 85668727,
      "end": 85780924,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 85513130,
      "end": 86513129,
      "genes": [
        {
          "symbol": "DLG2",
          "ensemblId": "ENSG00000150672",
          "biotype": "protein_coding",
          "start": 83455012,
          "end": 85628399,
          "strand": "-",
          "slug": "dlg2"
        },
        {
          "symbol": "TMEM126B",
          "ensemblId": "ENSG00000171204",
          "biotype": "protein_coding",
          "start": 85628556,
          "end": 85638965,
          "strand": "+",
          "slug": "tmem126b"
        },
        {
          "symbol": "TMEM126A",
          "ensemblId": "ENSG00000171202",
          "biotype": "protein_coding",
          "start": 85647956,
          "end": 85656547,
          "strand": "+",
          "slug": "tmem126a"
        },
        {
          "symbol": "CREBZF",
          "ensemblId": "ENSG00000137504",
          "biotype": "protein_coding",
          "start": 85657742,
          "end": 85682908,
          "strand": "-",
          "slug": "crebzf"
        },
        {
          "symbol": "CCDC89",
          "ensemblId": "ENSG00000179071",
          "biotype": "protein_coding",
          "start": 85683848,
          "end": 85686195,
          "strand": "-",
          "slug": "ccdc89"
        },
        {
          "symbol": "SYTL2",
          "ensemblId": "ENSG00000137501",
          "biotype": "protein_coding",
          "start": 85694224,
          "end": 85811182,
          "strand": "-",
          "slug": "sytl2"
        },
        {
          "symbol": "CCDC83",
          "ensemblId": "ENSG00000150676",
          "biotype": "protein_coding",
          "start": 85828907,
          "end": 85920021,
          "strand": "+",
          "slug": "ccdc83"
        },
        {
          "symbol": "EED",
          "ensemblId": "ENSG00000074266",
          "biotype": "protein_coding",
          "start": 86201212,
          "end": 86279811,
          "strand": "+",
          "slug": "eed"
        },
        {
          "symbol": "HIKESHI",
          "ensemblId": "ENSG00000149196",
          "biotype": "protein_coding",
          "start": 86302181,
          "end": 86346246,
          "strand": "+",
          "slug": "hikeshi"
        },
        {
          "symbol": "CCDC81",
          "ensemblId": "ENSG00000149201",
          "biotype": "protein_coding",
          "start": 86374736,
          "end": 86423109,
          "strand": "+",
          "slug": "ccdc81"
        },
        {
          "symbol": "ME3",
          "ensemblId": "ENSG00000151376",
          "biotype": "protein_coding",
          "start": 86438751,
          "end": 86672636,
          "strand": "-",
          "slug": "me3"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "acute-myeloid-leukemia",
        "name": "Acute myeloid leukemia",
        "systems": [
          "abnormality-of-blood-and-blood-forming-tissues",
          "abnormality-of-the-immune-system",
          "neoplasm"
        ],
        "url": "https://dantelabs.com/traits/acute-myeloid-leukemia"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}