{
  "url": "https://dantelabs.com/fi/genes/adam10",
  "gene": {
    "slug": "adam10",
    "symbol": "ADAM10",
    "name": "ADAM metallopeptidase domain 10",
    "hgnc": "HGNC:188",
    "summary": null,
    "location": "15q21.3",
    "locusType": "gene with protein product",
    "aliases": [
      "kuz",
      "MADM",
      "HsT18717",
      "CD156C"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000137845",
    "entrezId": 102,
    "omim": [
      "602192"
    ],
    "uniprot": [
      "O14672"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "15",
      "start": 58588809,
      "end": 58749707,
      "strand": "-",
      "ensemblTranscript": "ENST00000260408.8",
      "refseqTranscript": "NM_001110.4",
      "ensemblProtein": "ENSP00000260408.3",
      "refseqProtein": "NP_001101.1",
      "exons": [
        {
          "start": 58588809,
          "end": 58597641
        },
        {
          "start": 58599598,
          "end": 58599724
        },
        {
          "start": 58610297,
          "end": 58610517
        },
        {
          "start": 58610999,
          "end": 58611107
        },
        {
          "start": 58611808,
          "end": 58611991
        },
        {
          "start": 58621471,
          "end": 58621621
        },
        {
          "start": 58627700,
          "end": 58627883
        },
        {
          "start": 58633196,
          "end": 58633359
        },
        {
          "start": 58640777,
          "end": 58640960
        },
        {
          "start": 58643886,
          "end": 58643978
        },
        {
          "start": 58646055,
          "end": 58646204
        },
        {
          "start": 58665097,
          "end": 58665197
        },
        {
          "start": 58679124,
          "end": 58679282
        },
        {
          "start": 58682196,
          "end": 58682314
        },
        {
          "start": 58717577,
          "end": 58717727
        },
        {
          "start": 58749480,
          "end": 58749707
        }
      ],
      "cds": {
        "start": 58597547,
        "end": 58749534
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "15",
      "start": 58887403,
      "end": 59042177,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 58169258,
      "end": 59169257,
      "genes": [
        {
          "symbol": "ALDH1A2",
          "ensemblId": "ENSG00000128918",
          "biotype": "protein_coding",
          "start": 57953424,
          "end": 58497866,
          "strand": "-",
          "slug": "aldh1a2"
        },
        {
          "symbol": "AQP9",
          "ensemblId": "ENSG00000103569",
          "biotype": "protein_coding",
          "start": 58138169,
          "end": 58185915,
          "strand": "+",
          "slug": "aqp9"
        },
        {
          "symbol": "LIPC",
          "ensemblId": "ENSG00000166035",
          "biotype": "protein_coding",
          "start": 58410380,
          "end": 58570449,
          "strand": "+",
          "slug": "lipc"
        },
        {
          "symbol": "MINDY2",
          "ensemblId": "ENSG00000128923",
          "biotype": "protein_coding",
          "start": 58771117,
          "end": 58861900,
          "strand": "+",
          "slug": "mindy2"
        },
        {
          "symbol": "RNF111",
          "ensemblId": "ENSG00000157450",
          "biotype": "protein_coding",
          "start": 58865175,
          "end": 59097508,
          "strand": "+",
          "slug": "rnf111"
        },
        {
          "symbol": "SLTM",
          "ensemblId": "ENSG00000137776",
          "biotype": "protein_coding",
          "start": 58879046,
          "end": 58934012,
          "strand": "-",
          "slug": "sltm"
        },
        {
          "symbol": "CCNB2",
          "ensemblId": "ENSG00000157456",
          "biotype": "protein_coding",
          "start": 59105066,
          "end": 59126030,
          "strand": "+",
          "slug": "ccnb2"
        },
        {
          "symbol": "MYO1E",
          "ensemblId": "ENSG00000157483",
          "biotype": "protein_coding",
          "start": 59132409,
          "end": 59373121,
          "strand": "-",
          "slug": "myo1e"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "macule",
        "name": "Flat, discolored area of skin",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/macule"
      },
      {
        "slug": "hyperkeratosis",
        "name": "Hyperkeratosis",
        "systems": [
          "abnormality-of-the-integument"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hyperkeratosis"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}