{
  "url": "https://dantelabs.com/traits/persistent-ebv-viremia",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "persistent-ebv-viremia",
    "id": "HP:0020072",
    "name": "Persistent EBV viremia",
    "definition": "Persistent or recurrent detection of Epstein-Barr virus (EBV) in the blood that occurs in the context of unusual susceptibility to infection.",
    "synonyms": [
      "Chronic EBV viremia",
      "Persistent EBV viraemia",
      "Recurrent EBV viremia"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-immune-system",
        "name": "Abnormality of the immune system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-immune-system"
      }
    ],
    "broader": [
      {
        "slug": "persistent-viremia",
        "name": "Persistent viremia",
        "url": "https://dantelabs.com/traits/persistent-viremia"
      },
      {
        "slug": "unusual-ebv-infection",
        "name": "Unusual EBV infection",
        "url": "https://dantelabs.com/traits/unusual-ebv-infection"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cd28",
        "symbol": "CD28",
        "hgnc": "HGNC:1653",
        "name": "CD28 molecule",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd28"
      },
      {
        "slug": "irf4",
        "symbol": "IRF4",
        "hgnc": "HGNC:6119",
        "name": "interferon regulatory factor 4",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/irf4"
      },
      {
        "slug": "itk",
        "symbol": "ITK",
        "hgnc": "HGNC:6171",
        "name": "IL2 inducible T cell kinase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itk"
      },
      {
        "slug": "itpr3",
        "symbol": "ITPR3",
        "hgnc": "HGNC:6182",
        "name": "inositol 1,4,5-trisphosphate receptor type 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itpr3"
      },
      {
        "slug": "magt1",
        "symbol": "MAGT1",
        "hgnc": "HGNC:28880",
        "name": "magnesium transporter 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/magt1"
      },
      {
        "slug": "prkcd",
        "symbol": "PRKCD",
        "hgnc": "HGNC:9399",
        "name": "protein kinase C delta",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prkcd"
      },
      {
        "slug": "tnfrsf9",
        "symbol": "TNFRSF9",
        "hgnc": "HGNC:11924",
        "name": "TNF receptor superfamily member 9",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf9"
      },
      {
        "slug": "cd27",
        "symbol": "CD27",
        "hgnc": "HGNC:11922",
        "name": "CD27 molecule",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cd27"
      },
      {
        "slug": "def6",
        "symbol": "DEF6",
        "hgnc": "HGNC:2760",
        "name": "DEF6 guanine nucleotide exchange factor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/def6"
      },
      {
        "slug": "flt3lg",
        "symbol": "FLT3LG",
        "hgnc": "HGNC:3766",
        "name": "fms related receptor tyrosine kinase 3 ligand",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flt3lg"
      },
      {
        "slug": "ikzf3",
        "symbol": "IKZF3",
        "hgnc": "HGNC:13178",
        "name": "IKAROS family zinc finger 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ikzf3"
      },
      {
        "slug": "il27ra",
        "symbol": "IL27RA",
        "hgnc": "HGNC:17290",
        "name": "interleukin 27 receptor subunit alpha",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/il27ra"
      },
      {
        "slug": "lat",
        "symbol": "LAT",
        "hgnc": "HGNC:18874",
        "name": "linker for activation of T cells",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lat"
      },
      {
        "slug": "pgm3",
        "symbol": "PGM3",
        "hgnc": "HGNC:8907",
        "name": "phosphoglucomutase 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pgm3"
      },
      {
        "slug": "stk4",
        "symbol": "STK4",
        "hgnc": "HGNC:11408",
        "name": "serine/threonine kinase 4",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stk4"
      },
      {
        "slug": "tet2",
        "symbol": "TET2",
        "hgnc": "HGNC:25941",
        "name": "tet methylcytosine dioxygenase 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tet2"
      },
      {
        "slug": "tom1",
        "symbol": "TOM1",
        "hgnc": "HGNC:11982",
        "name": "target of myb1 membrane trafficking protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tom1"
      },
      {
        "slug": "trac",
        "symbol": "TRAC",
        "hgnc": "HGNC:12029",
        "name": "T cell receptor alpha constant",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/trac"
      },
      {
        "slug": "pik3r1",
        "symbol": "PIK3R1",
        "hgnc": "HGNC:8979",
        "name": "phosphoinositide-3-kinase regulatory subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3r1"
      }
    ]
  }
}