{
  "url": "https://dantelabs.com/traits/acholic-stools",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "acholic-stools",
    "id": "HP:0011985",
    "name": "Clay colored stools",
    "label": "Acholic stools",
    "definition": "Clay colored stools lacking bile pigment.",
    "synonyms": [
      "Acholia",
      "Clay coloured stools",
      "Discolored, acholic stools"
    ],
    "systems": [
      {
        "slug": "abnormality-of-metabolism-homeostasis",
        "name": "Laboratory abnormality",
        "url": "https://dantelabs.com/traits/abnormality-of-metabolism-homeostasis"
      },
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-stool-composition",
        "name": "Abnormal stool composition",
        "url": "https://dantelabs.com/traits/abnormal-stool-composition"
      },
      {
        "slug": "cholestasis",
        "name": "Slowed or blocked flow of bile from liver",
        "url": "https://dantelabs.com/traits/cholestasis"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "cyp7b1",
        "symbol": "CYP7B1",
        "hgnc": "HGNC:2652",
        "name": "cytochrome P450 family 7 subfamily B member 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cyp7b1"
      },
      {
        "slug": "brca1",
        "symbol": "BRCA1",
        "hgnc": "HGNC:1100",
        "name": "BRCA1 DNA repair associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca1"
      },
      {
        "slug": "brca2",
        "symbol": "BRCA2",
        "hgnc": "HGNC:1101",
        "name": "BRCA2 DNA repair associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/brca2"
      },
      {
        "slug": "ptpn3",
        "symbol": "PTPN3",
        "hgnc": "HGNC:9655",
        "name": "protein tyrosine phosphatase non-receptor type 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ptpn3"
      },
      {
        "slug": "ros1",
        "symbol": "ROS1",
        "hgnc": "HGNC:10261",
        "name": "ROS proto-oncogene 1, receptor tyrosine kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ros1"
      },
      {
        "slug": "dcdc2",
        "symbol": "DCDC2",
        "hgnc": "HGNC:18141",
        "name": "doublecortin domain containing 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dcdc2"
      },
      {
        "slug": "hsd3b7",
        "symbol": "HSD3B7",
        "hgnc": "HGNC:18324",
        "name": "hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hsd3b7"
      },
      {
        "slug": "myo5b",
        "symbol": "MYO5B",
        "hgnc": "HGNC:7603",
        "name": "myosin VB",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myo5b"
      },
      {
        "slug": "rfx6",
        "symbol": "RFX6",
        "hgnc": "HGNC:21478",
        "name": "regulatory factor X6",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rfx6"
      }
    ]
  }
}