{
  "url": "https://dantelabs.com/traits/abnormal-trabecular-bone-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-trabecular-bone-morphology",
    "id": "HP:0100671",
    "name": "Abnormal trabecular bone morphology",
    "definition": "Abnormal structure or form of trabecular bone.",
    "synonyms": [
      "Abnormal shape of spongy bone",
      "Abnormality of bone trabeculation"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-musculoskeletal-system",
        "name": "Abnormality of the musculoskeletal system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-musculoskeletal-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-bone-structure",
        "name": "Abnormal bone structure",
        "url": "https://dantelabs.com/traits/abnormal-bone-structure"
      }
    ],
    "narrower": [
      {
        "slug": "coarse-metaphyseal-trabecularization",
        "name": "Coarse metaphyseal trabecularization",
        "genes": 25,
        "url": "https://dantelabs.com/traits/coarse-metaphyseal-trabecularization"
      },
      {
        "slug": "sparse-bone-trabeculae",
        "name": "Sparse bone trabeculae",
        "genes": 5,
        "url": "https://dantelabs.com/traits/sparse-bone-trabeculae"
      }
    ],
    "genes": [
      {
        "slug": "dmp1",
        "symbol": "DMP1",
        "hgnc": "HGNC:2932",
        "name": "dentin matrix acidic phosphoprotein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dmp1"
      },
      {
        "slug": "enpp1",
        "symbol": "ENPP1",
        "hgnc": "HGNC:3356",
        "name": "ectonucleotide pyrophosphatase/phosphodiesterase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/enpp1"
      },
      {
        "slug": "pth1r",
        "symbol": "PTH1R",
        "hgnc": "HGNC:9608",
        "name": "parathyroid hormone 1 receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pth1r"
      },
      {
        "slug": "anapc1",
        "symbol": "ANAPC1",
        "hgnc": "HGNC:19988",
        "name": "anaphase promoting complex subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/anapc1"
      },
      {
        "slug": "recql4",
        "symbol": "RECQL4",
        "hgnc": "HGNC:9949",
        "name": "RecQ like helicase 4",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/recql4"
      },
      {
        "slug": "tnfrsf11a",
        "symbol": "TNFRSF11A",
        "hgnc": "HGNC:11908",
        "name": "TNF receptor superfamily member 11a",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf11a"
      }
    ]
  }
}