{
  "url": "https://dantelabs.com/traits/abnormal-retinal-pigmentation",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-retinal-pigmentation",
    "id": "HP:0007703",
    "name": "Abnormal retinal pigmentation",
    "definition": "Any deviation from the normal pigmentation of the retina.",
    "synonyms": [
      "Abnormality of retinal pigment epithelium",
      "Abnormality of retinal pigmentation",
      "Abnormality of RPE",
      "Retinal pigmentary anomaly"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-retinal-morphology",
        "name": "Retina issue",
        "url": "https://dantelabs.com/traits/abnormal-retinal-morphology"
      }
    ],
    "narrower": [
      {
        "slug": "pigmentary-retinopathy",
        "name": "Pigmentary retinopathy",
        "genes": 127,
        "url": "https://dantelabs.com/traits/pigmentary-retinopathy"
      },
      {
        "slug": "retinal-pigment-epithelial-mottling",
        "name": "Retinal pigment epithelial mottling",
        "genes": 50,
        "url": "https://dantelabs.com/traits/retinal-pigment-epithelial-mottling"
      },
      {
        "slug": "nummular-pigmentation-of-the-retina",
        "name": "Nummular pigmentation of the retina",
        "genes": 5,
        "url": "https://dantelabs.com/traits/nummular-pigmentation-of-the-retina"
      }
    ],
    "genes": [
      {
        "slug": "abca4",
        "symbol": "ABCA4",
        "hgnc": "HGNC:34",
        "name": "ATP binding cassette subfamily A member 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/abca4"
      },
      {
        "slug": "adam9",
        "symbol": "ADAM9",
        "hgnc": "HGNC:216",
        "name": "ADAM metallopeptidase domain 9",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adam9"
      },
      {
        "slug": "agbl5",
        "symbol": "AGBL5",
        "hgnc": "HGNC:26147",
        "name": "AGBL carboxypeptidase 5",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/agbl5"
      },
      {
        "slug": "ahi1",
        "symbol": "AHI1",
        "hgnc": "HGNC:21575",
        "name": "Abelson helper integration site 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahi1"
      },
      {
        "slug": "ahr",
        "symbol": "AHR",
        "hgnc": "HGNC:348",
        "name": "aryl hydrocarbon receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ahr"
      },
      {
        "slug": "aipl1",
        "symbol": "AIPL1",
        "hgnc": "HGNC:359",
        "name": "AIP like 1 HSP90 co-chaperone",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/aipl1"
      },
      {
        "slug": "alms1",
        "symbol": "ALMS1",
        "hgnc": "HGNC:428",
        "name": "ALMS1 centrosome and basal body associated protein",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/alms1"
      },
      {
        "slug": "arhgef18",
        "symbol": "ARHGEF18",
        "hgnc": "HGNC:17090",
        "name": "Rho/Rac guanine nucleotide exchange factor 18",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arhgef18"
      },
      {
        "slug": "arl2bp",
        "symbol": "ARL2BP",
        "hgnc": "HGNC:17146",
        "name": "ARF like GTPase 2 binding protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arl2bp"
      },
      {
        "slug": "arl3",
        "symbol": "ARL3",
        "hgnc": "HGNC:694",
        "name": "ARF like GTPase 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arl3"
      },
      {
        "slug": "arl6",
        "symbol": "ARL6",
        "hgnc": "HGNC:13210",
        "name": "ARF like GTPase 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/arl6"
      },
      {
        "slug": "atf6",
        "symbol": "ATF6",
        "hgnc": "HGNC:791",
        "name": "activating transcription factor 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/atf6"
      },
      {
        "slug": "bbs1",
        "symbol": "BBS1",
        "hgnc": "HGNC:966",
        "name": "Bardet-Biedl syndrome 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs1"
      },
      {
        "slug": "bbs2",
        "symbol": "BBS2",
        "hgnc": "HGNC:967",
        "name": "Bardet-Biedl syndrome 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/bbs2"
      },
      {
        "slug": "best1",
        "symbol": "BEST1",
        "hgnc": "HGNC:12703",
        "name": "bestrophin 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/best1"
      },
      {
        "slug": "ca4",
        "symbol": "CA4",
        "hgnc": "HGNC:1375",
        "name": "carbonic anhydrase 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ca4"
      },
      {
        "slug": "cabp4",
        "symbol": "CABP4",
        "hgnc": "HGNC:1386",
        "name": "calcium binding protein 4",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cabp4"
      },
      {
        "slug": "cacna1f",
        "symbol": "CACNA1F",
        "hgnc": "HGNC:1393",
        "name": "calcium voltage-gated channel subunit alpha1 F",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna1f"
      },
      {
        "slug": "cacna2d4",
        "symbol": "CACNA2D4",
        "hgnc": "HGNC:20202",
        "name": "calcium voltage-gated channel auxiliary subunit alpha2delta 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cacna2d4"
      },
      {
        "slug": "cc2d2a",
        "symbol": "CC2D2A",
        "hgnc": "HGNC:29253",
        "name": "coiled-coil and C2 domain containing 2A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cc2d2a"
      },
      {
        "slug": "cdh3",
        "symbol": "CDH3",
        "hgnc": "HGNC:1762",
        "name": "cadherin 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cdh3"
      },
      {
        "slug": "cdhr1",
        "symbol": "CDHR1",
        "hgnc": "HGNC:14550",
        "name": "cadherin related family member 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cdhr1"
      },
      {
        "slug": "cep164",
        "symbol": "CEP164",
        "hgnc": "HGNC:29182",
        "name": "centrosomal protein 164",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep164"
      },
      {
        "slug": "cep290",
        "symbol": "CEP290",
        "hgnc": "HGNC:29021",
        "name": "centrosomal protein 290",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cep290"
      },
      {
        "slug": "cerkl",
        "symbol": "CERKL",
        "hgnc": "HGNC:21699",
        "name": "CERK like autophagy regulator",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cerkl"
      },
      {
        "slug": "cfap20",
        "symbol": "CFAP20",
        "hgnc": "HGNC:29523",
        "name": "cilia and flagella associated protein 20",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap20"
      },
      {
        "slug": "cfap410",
        "symbol": "CFAP410",
        "hgnc": "HGNC:1260",
        "name": "cilia and flagella associated protein 410",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfap410"
      },
      {
        "slug": "cfap418",
        "symbol": "CFAP418",
        "hgnc": "HGNC:27232",
        "name": "cilia and flagella associated protein 418",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/cfap418"
      },
      {
        "slug": "chm",
        "symbol": "CHM",
        "hgnc": "HGNC:1940",
        "name": "CHM Rab escort protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chm"
      },
      {
        "slug": "cldn19",
        "symbol": "CLDN19",
        "hgnc": "HGNC:2040",
        "name": "claudin 19",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cldn19"
      },
      {
        "slug": "clrn1",
        "symbol": "CLRN1",
        "hgnc": "HGNC:12605",
        "name": "clarin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clrn1"
      },
      {
        "slug": "cnga1",
        "symbol": "CNGA1",
        "hgnc": "HGNC:2148",
        "name": "cyclic nucleotide gated channel subunit alpha 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnga1"
      },
      {
        "slug": "cnga3",
        "symbol": "CNGA3",
        "hgnc": "HGNC:2150",
        "name": "cyclic nucleotide gated channel subunit alpha 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnga3"
      },
      {
        "slug": "cngb1",
        "symbol": "CNGB1",
        "hgnc": "HGNC:2151",
        "name": "cyclic nucleotide gated channel subunit beta 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cngb1"
      },
      {
        "slug": "cngb3",
        "symbol": "CNGB3",
        "hgnc": "HGNC:2153",
        "name": "cyclic nucleotide gated channel subunit beta 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cngb3"
      },
      {
        "slug": "cnnm4",
        "symbol": "CNNM4",
        "hgnc": "HGNC:105",
        "name": "cyclin and CBS domain divalent metal cation transport mediator 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cnnm4"
      },
      {
        "slug": "coq8b",
        "symbol": "COQ8B",
        "hgnc": "HGNC:19041",
        "name": "coenzyme Q8B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/coq8b"
      },
      {
        "slug": "crb1",
        "symbol": "CRB1",
        "hgnc": "HGNC:2343",
        "name": "crumbs cell polarity complex component 1",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/crb1"
      },
      {
        "slug": "crx",
        "symbol": "CRX",
        "hgnc": "HGNC:2383",
        "name": "cone-rod homeobox",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/crx"
      },
      {
        "slug": "dhdds",
        "symbol": "DHDDS",
        "hgnc": "HGNC:20603",
        "name": "dehydrodolichyl diphosphate synthase subunit",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhdds"
      },
      {
        "slug": "dhx38",
        "symbol": "DHX38",
        "hgnc": "HGNC:17211",
        "name": "DEAH-box helicase 38",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dhx38"
      },
      {
        "slug": "dram2",
        "symbol": "DRAM2",
        "hgnc": "HGNC:28769",
        "name": "DNA damage regulated autophagy modulator 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dram2"
      },
      {
        "slug": "epg5",
        "symbol": "EPG5",
        "hgnc": "HGNC:29331",
        "name": "ectopic P-granules 5 autophagy tethering factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/epg5"
      },
      {
        "slug": "eys",
        "symbol": "EYS",
        "hgnc": "HGNC:21555",
        "name": "EGF-like photoreceptor maintenance factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/eys"
      },
      {
        "slug": "fam161a",
        "symbol": "FAM161A",
        "hgnc": "HGNC:25808",
        "name": "FAM161 centrosomal protein A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fam161a"
      },
      {
        "slug": "fscn2",
        "symbol": "FSCN2",
        "hgnc": "HGNC:3960",
        "name": "fascin actin-bundling protein 2, retinal",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/fscn2"
      },
      {
        "slug": "fsd1l",
        "symbol": "FSD1L",
        "hgnc": "HGNC:13753",
        "name": "fibronectin type III and SPRY domain containing 1 like",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/fsd1l"
      },
      {
        "slug": "gdf6",
        "symbol": "GDF6",
        "hgnc": "HGNC:4221",
        "name": "growth differentiation factor 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gdf6"
      },
      {
        "slug": "gnat2",
        "symbol": "GNAT2",
        "hgnc": "HGNC:4394",
        "name": "G protein subunit alpha transducin 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/gnat2"
      },
      {
        "slug": "guca1a",
        "symbol": "GUCA1A",
        "hgnc": "HGNC:4678",
        "name": "guanylate cyclase activator 1A",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/guca1a"
      },
      {
        "slug": "guca1b",
        "symbol": "GUCA1B",
        "hgnc": "HGNC:4679",
        "name": "guanylate cyclase activator 1B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/guca1b"
      },
      {
        "slug": "gucy2d",
        "symbol": "GUCY2D",
        "hgnc": "HGNC:4689",
        "name": "guanylate cyclase 2D, retinal",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/gucy2d"
      },
      {
        "slug": "hgsnat",
        "symbol": "HGSNAT",
        "hgnc": "HGNC:26527",
        "name": "heparan-alpha-glucosaminide N-acetyltransferase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hgsnat"
      },
      {
        "slug": "hkdc1",
        "symbol": "HKDC1",
        "hgnc": "HGNC:23302",
        "name": "hexokinase domain containing 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hkdc1"
      },
      {
        "slug": "idh3a",
        "symbol": "IDH3A",
        "hgnc": "HGNC:5384",
        "name": "isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh3a"
      },
      {
        "slug": "idh3b",
        "symbol": "IDH3B",
        "hgnc": "HGNC:5385",
        "name": "isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/idh3b"
      },
      {
        "slug": "ift140",
        "symbol": "IFT140",
        "hgnc": "HGNC:29077",
        "name": "intraflagellar transport 140",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ift140"
      },
      {
        "slug": "ift172",
        "symbol": "IFT172",
        "hgnc": "HGNC:30391",
        "name": "intraflagellar transport 172",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/ift172"
      },
      {
        "slug": "ift43",
        "symbol": "IFT43",
        "hgnc": "HGNC:29669",
        "name": "intraflagellar transport 43",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift43"
      },
      {
        "slug": "ift54",
        "symbol": "IFT54",
        "hgnc": "HGNC:17861",
        "name": "intraflagellar transport 54",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift54"
      },
      {
        "slug": "ift88",
        "symbol": "IFT88",
        "hgnc": "HGNC:20606",
        "name": "intraflagellar transport 88",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift88"
      },
      {
        "slug": "impdh1",
        "symbol": "IMPDH1",
        "hgnc": "HGNC:6052",
        "name": "inosine monophosphate dehydrogenase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/impdh1"
      },
      {
        "slug": "impg1",
        "symbol": "IMPG1",
        "hgnc": "HGNC:6055",
        "name": "interphotoreceptor matrix proteoglycan 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/impg1"
      },
      {
        "slug": "impg2",
        "symbol": "IMPG2",
        "hgnc": "HGNC:18362",
        "name": "interphotoreceptor matrix proteoglycan 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/impg2"
      },
      {
        "slug": "invs",
        "symbol": "INVS",
        "hgnc": "HGNC:17870",
        "name": "inversin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/invs"
      },
      {
        "slug": "iqcb1",
        "symbol": "IQCB1",
        "hgnc": "HGNC:28949",
        "name": "IQ motif containing B1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/iqcb1"
      },
      {
        "slug": "kcnj13",
        "symbol": "KCNJ13",
        "hgnc": "HGNC:6259",
        "name": "potassium inwardly rectifying channel subfamily J member 13",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kcnj13"
      },
      {
        "slug": "kiaa1549",
        "symbol": "KIAA1549",
        "hgnc": "HGNC:22219",
        "name": "KIAA1549",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa1549"
      },
      {
        "slug": "kiz",
        "symbol": "KIZ",
        "hgnc": "HGNC:15865",
        "name": "kizuna centrosomal protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiz"
      },
      {
        "slug": "klhl7",
        "symbol": "KLHL7",
        "hgnc": "HGNC:15646",
        "name": "kelch like family member 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/klhl7"
      },
      {
        "slug": "lca5",
        "symbol": "LCA5",
        "hgnc": "HGNC:31923",
        "name": "lebercilin LCA5",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/lca5"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "lrat",
        "symbol": "LRAT",
        "hgnc": "HGNC:6685",
        "name": "lecithin retinol acyltransferase",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/lrat"
      },
      {
        "slug": "mak",
        "symbol": "MAK",
        "hgnc": "HGNC:6816",
        "name": "male germ cell associated kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mak"
      },
      {
        "slug": "mertk",
        "symbol": "MERTK",
        "hgnc": "HGNC:7027",
        "name": "MER proto-oncogene, tyrosine kinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mertk"
      },
      {
        "slug": "mfsd8",
        "symbol": "MFSD8",
        "hgnc": "HGNC:28486",
        "name": "major facilitator superfamily domain containing 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mfsd8"
      },
      {
        "slug": "nek2",
        "symbol": "NEK2",
        "hgnc": "HGNC:7745",
        "name": "NIMA related kinase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nek2"
      },
      {
        "slug": "nmnat1",
        "symbol": "NMNAT1",
        "hgnc": "HGNC:17877",
        "name": "nicotinamide nucleotide adenylyltransferase 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/nmnat1"
      },
      {
        "slug": "nphp1",
        "symbol": "NPHP1",
        "hgnc": "HGNC:7905",
        "name": "nephrocystin 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp1"
      },
      {
        "slug": "nphp3",
        "symbol": "NPHP3",
        "hgnc": "HGNC:7907",
        "name": "nephrocystin 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp3"
      },
      {
        "slug": "nphp4",
        "symbol": "NPHP4",
        "hgnc": "HGNC:19104",
        "name": "nephrocystin 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nphp4"
      },
      {
        "slug": "nr2e3",
        "symbol": "NR2E3",
        "hgnc": "HGNC:7974",
        "name": "nuclear receptor subfamily 2 group E member 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nr2e3"
      },
      {
        "slug": "nrl",
        "symbol": "NRL",
        "hgnc": "HGNC:8002",
        "name": "neural retina leucine zipper",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nrl"
      },
      {
        "slug": "ofd1",
        "symbol": "OFD1",
        "hgnc": "HGNC:2567",
        "name": "OFD1 centriole and centriolar satellite protein",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ofd1"
      },
      {
        "slug": "opn1lw",
        "symbol": "OPN1LW",
        "hgnc": "HGNC:9936",
        "name": "opsin 1, long wave sensitive",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/opn1lw"
      },
      {
        "slug": "opn1mw",
        "symbol": "OPN1MW",
        "hgnc": "HGNC:4206",
        "name": "opsin 1, medium wave sensitive",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/opn1mw"
      },
      {
        "slug": "otx2",
        "symbol": "OTX2",
        "hgnc": "HGNC:8522",
        "name": "orthodenticle homeobox 2",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/otx2"
      },
      {
        "slug": "pax6",
        "symbol": "PAX6",
        "hgnc": "HGNC:8620",
        "name": "paired box 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pax6"
      },
      {
        "slug": "pcare",
        "symbol": "PCARE",
        "hgnc": "HGNC:34383",
        "name": "photoreceptor cilium actin regulator",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pcare"
      },
      {
        "slug": "pcyt1a",
        "symbol": "PCYT1A",
        "hgnc": "HGNC:8754",
        "name": "phosphate cytidylyltransferase 1A, choline",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/pcyt1a"
      },
      {
        "slug": "pde6a",
        "symbol": "PDE6A",
        "hgnc": "HGNC:8785",
        "name": "phosphodiesterase 6A",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6a"
      },
      {
        "slug": "pde6b",
        "symbol": "PDE6B",
        "hgnc": "HGNC:8786",
        "name": "phosphodiesterase 6B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6b"
      },
      {
        "slug": "pde6c",
        "symbol": "PDE6C",
        "hgnc": "HGNC:8787",
        "name": "phosphodiesterase 6C",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6c"
      },
      {
        "slug": "pde6g",
        "symbol": "PDE6G",
        "hgnc": "HGNC:8789",
        "name": "phosphodiesterase 6G",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pde6g"
      },
      {
        "slug": "pex7",
        "symbol": "PEX7",
        "hgnc": "HGNC:8860",
        "name": "peroxisomal biogenesis factor 7",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex7"
      },
      {
        "slug": "phyh",
        "symbol": "PHYH",
        "hgnc": "HGNC:8940",
        "name": "phytanoyl-CoA 2-hydroxylase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/phyh"
      },
      {
        "slug": "pitpnm3",
        "symbol": "PITPNM3",
        "hgnc": "HGNC:21043",
        "name": "PITPNM family member 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pitpnm3"
      },
      {
        "slug": "plk4",
        "symbol": "PLK4",
        "hgnc": "HGNC:11397",
        "name": "polo like kinase 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plk4"
      },
      {
        "slug": "pnpla6",
        "symbol": "PNPLA6",
        "hgnc": "HGNC:16268",
        "name": "patatin like domain 6, lysophospholipase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pnpla6"
      },
      {
        "slug": "poc1b",
        "symbol": "POC1B",
        "hgnc": "HGNC:30836",
        "name": "POC1 centriolar protein B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/poc1b"
      },
      {
        "slug": "pomgnt1",
        "symbol": "POMGNT1",
        "hgnc": "HGNC:19139",
        "name": "protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pomgnt1"
      },
      {
        "slug": "prcd",
        "symbol": "PRCD",
        "hgnc": "HGNC:32528",
        "name": "photoreceptor disc component",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prcd"
      },
      {
        "slug": "prom1",
        "symbol": "PROM1",
        "hgnc": "HGNC:9454",
        "name": "prominin 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/prom1"
      },
      {
        "slug": "prpf3",
        "symbol": "PRPF3",
        "hgnc": "HGNC:17348",
        "name": "pre-mRNA processing factor 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf3"
      },
      {
        "slug": "prpf31",
        "symbol": "PRPF31",
        "hgnc": "HGNC:15446",
        "name": "pre-mRNA processing factor 31",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf31"
      },
      {
        "slug": "prpf4",
        "symbol": "PRPF4",
        "hgnc": "HGNC:17349",
        "name": "pre-mRNA splicing tri-snRNP complex factor PRPF4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf4"
      },
      {
        "slug": "prpf6",
        "symbol": "PRPF6",
        "hgnc": "HGNC:15860",
        "name": "pre-mRNA processing factor 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf6"
      },
      {
        "slug": "prpf8",
        "symbol": "PRPF8",
        "hgnc": "HGNC:17340",
        "name": "pre-mRNA processing factor 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prpf8"
      },
      {
        "slug": "prph2",
        "symbol": "PRPH2",
        "hgnc": "HGNC:9942",
        "name": "peripherin 2",
        "frequency": "very-frequent",
        "diseases": 4,
        "url": "https://dantelabs.com/genes/prph2"
      },
      {
        "slug": "rab28",
        "symbol": "RAB28",
        "hgnc": "HGNC:9768",
        "name": "RAB28, member RAS oncogene family",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab28"
      },
      {
        "slug": "rax2",
        "symbol": "RAX2",
        "hgnc": "HGNC:18286",
        "name": "retina and anterior neural fold homeobox 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rax2"
      },
      {
        "slug": "rbp3",
        "symbol": "RBP3",
        "hgnc": "HGNC:9921",
        "name": "retinol binding protein 3",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rbp3"
      },
      {
        "slug": "rd3",
        "symbol": "RD3",
        "hgnc": "HGNC:19689",
        "name": "RD3 regulator of GUCY2D",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rd3"
      },
      {
        "slug": "rdh12",
        "symbol": "RDH12",
        "hgnc": "HGNC:19977",
        "name": "retinol dehydrogenase 12",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rdh12"
      },
      {
        "slug": "reep6",
        "symbol": "REEP6",
        "hgnc": "HGNC:30078",
        "name": "receptor accessory protein 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/reep6"
      },
      {
        "slug": "rgr",
        "symbol": "RGR",
        "hgnc": "HGNC:9990",
        "name": "retinal G protein coupled receptor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rgr"
      },
      {
        "slug": "rho",
        "symbol": "RHO",
        "hgnc": "HGNC:10012",
        "name": "rhodopsin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rho"
      },
      {
        "slug": "rims1",
        "symbol": "RIMS1",
        "hgnc": "HGNC:17282",
        "name": "regulating synaptic membrane exocytosis 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rims1"
      },
      {
        "slug": "rlbp1",
        "symbol": "RLBP1",
        "hgnc": "HGNC:10024",
        "name": "retinaldehyde binding protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rlbp1"
      },
      {
        "slug": "rmrp",
        "symbol": "RMRP",
        "hgnc": "HGNC:10031",
        "name": "RNA component of mitochondrial RNA processing endoribonuclease",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rmrp"
      },
      {
        "slug": "rnf216",
        "symbol": "RNF216",
        "hgnc": "HGNC:21698",
        "name": "ring finger protein 216",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf216"
      },
      {
        "slug": "rnu4-2",
        "symbol": "RNU4-2",
        "hgnc": "HGNC:10193",
        "name": "RNA, U4 small nuclear 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4-2"
      },
      {
        "slug": "rnu6-1",
        "symbol": "RNU6-1",
        "hgnc": "HGNC:10227",
        "name": "RNA, U6 small nuclear 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-1"
      },
      {
        "slug": "rnu6-2",
        "symbol": "RNU6-2",
        "hgnc": "HGNC:34270",
        "name": "RNA, U6 small nuclear 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-2"
      },
      {
        "slug": "rnu6-8",
        "symbol": "RNU6-8",
        "hgnc": "HGNC:34285",
        "name": "RNA, U6 small nuclear 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-8"
      },
      {
        "slug": "rnu6-9",
        "symbol": "RNU6-9",
        "hgnc": "HGNC:34269",
        "name": "RNA, U6 small nuclear 9",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu6-9"
      },
      {
        "slug": "rom1",
        "symbol": "ROM1",
        "hgnc": "HGNC:10254",
        "name": "retinal outer segment membrane protein 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rom1"
      },
      {
        "slug": "rp1",
        "symbol": "RP1",
        "hgnc": "HGNC:10263",
        "name": "RP1 axonemal microtubule associated",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp1"
      },
      {
        "slug": "rp1l1",
        "symbol": "RP1L1",
        "hgnc": "HGNC:15946",
        "name": "RP1 like 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp1l1"
      },
      {
        "slug": "rp2",
        "symbol": "RP2",
        "hgnc": "HGNC:10274",
        "name": "RP2 activator of ARL3 GTPase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp2"
      },
      {
        "slug": "rp9",
        "symbol": "RP9",
        "hgnc": "HGNC:10288",
        "name": "RP9 pre-mRNA splicing factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rp9"
      },
      {
        "slug": "rpe65",
        "symbol": "RPE65",
        "hgnc": "HGNC:10294",
        "name": "retinoid isomerohydrolase RPE65",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/rpe65"
      },
      {
        "slug": "rpgr",
        "symbol": "RPGR",
        "hgnc": "HGNC:10295",
        "name": "retinitis pigmentosa GTPase regulator",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rpgr"
      },
      {
        "slug": "rpgrip1",
        "symbol": "RPGRIP1",
        "hgnc": "HGNC:13436",
        "name": "RPGR interacting protein 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/rpgrip1"
      },
      {
        "slug": "sag",
        "symbol": "SAG",
        "hgnc": "HGNC:10521",
        "name": "S-antigen visual arrestin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sag"
      },
      {
        "slug": "saxo6",
        "symbol": "SAXO6",
        "hgnc": "HGNC:29917",
        "name": "stabilizer of axonemal microtubules 6",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/saxo6"
      },
      {
        "slug": "scaper",
        "symbol": "SCAPER",
        "hgnc": "HGNC:13081",
        "name": "S-phase cyclin A associated protein in the ER",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/scaper"
      },
      {
        "slug": "sdccag8",
        "symbol": "SDCCAG8",
        "hgnc": "HGNC:10671",
        "name": "SHH signaling and ciliogenesis regulator SDCCAG8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sdccag8"
      },
      {
        "slug": "sema4a",
        "symbol": "SEMA4A",
        "hgnc": "HGNC:10729",
        "name": "semaphorin 4A",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/sema4a"
      },
      {
        "slug": "slc45a2",
        "symbol": "SLC45A2",
        "hgnc": "HGNC:16472",
        "name": "solute carrier family 45 member 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc45a2"
      },
      {
        "slug": "slc7a14",
        "symbol": "SLC7A14",
        "hgnc": "HGNC:29326",
        "name": "solute carrier family 7 member 14",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc7a14"
      },
      {
        "slug": "snrnp200",
        "symbol": "SNRNP200",
        "hgnc": "HGNC:30859",
        "name": "small nuclear ribonucleoprotein U5 subunit 200",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/snrnp200"
      },
      {
        "slug": "spata7",
        "symbol": "SPATA7",
        "hgnc": "HGNC:20423",
        "name": "spermatogenesis associated 7",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/spata7"
      },
      {
        "slug": "tlcd3b",
        "symbol": "TLCD3B",
        "hgnc": "HGNC:25295",
        "name": "TLC domain containing 3B",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tlcd3b"
      },
      {
        "slug": "tmem216",
        "symbol": "TMEM216",
        "hgnc": "HGNC:25018",
        "name": "transmembrane protein 216",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem216"
      },
      {
        "slug": "topors",
        "symbol": "TOPORS",
        "hgnc": "HGNC:21653",
        "name": "TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/topors"
      },
      {
        "slug": "ttc8",
        "symbol": "TTC8",
        "hgnc": "HGNC:20087",
        "name": "tetratricopeptide repeat domain 8",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc8"
      },
      {
        "slug": "ttll5",
        "symbol": "TTLL5",
        "hgnc": "HGNC:19963",
        "name": "tubulin tyrosine ligase like 5",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttll5"
      },
      {
        "slug": "tub",
        "symbol": "TUB",
        "hgnc": "HGNC:12406",
        "name": "TUB bipartite transcription factor",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tub"
      },
      {
        "slug": "tubb4b",
        "symbol": "TUBB4B",
        "hgnc": "HGNC:20771",
        "name": "tubulin beta 4B class IVb",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tubb4b"
      },
      {
        "slug": "tubgcp4",
        "symbol": "TUBGCP4",
        "hgnc": "HGNC:16691",
        "name": "tubulin gamma complex component 4",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tubgcp4"
      },
      {
        "slug": "tubgcp6",
        "symbol": "TUBGCP6",
        "hgnc": "HGNC:18127",
        "name": "tubulin gamma complex component 6",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tubgcp6"
      },
      {
        "slug": "tulp1",
        "symbol": "TULP1",
        "hgnc": "HGNC:12423",
        "name": "TUB like protein 1",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/tulp1"
      },
      {
        "slug": "tyr",
        "symbol": "TYR",
        "hgnc": "HGNC:12442",
        "name": "tyrosinase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyr"
      },
      {
        "slug": "ubap1l",
        "symbol": "UBAP1L",
        "hgnc": "HGNC:40028",
        "name": "ubiquitin associated protein 1 like",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ubap1l"
      },
      {
        "slug": "unc119",
        "symbol": "UNC119",
        "hgnc": "HGNC:12565",
        "name": "unc-119 lipid binding chaperone",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/unc119"
      },
      {
        "slug": "ush2a",
        "symbol": "USH2A",
        "hgnc": "HGNC:12601",
        "name": "usherin",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ush2a"
      },
      {
        "slug": "usp45",
        "symbol": "USP45",
        "hgnc": "HGNC:20080",
        "name": "ubiquitin specific peptidase 45",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/usp45"
      },
      {
        "slug": "wdr19",
        "symbol": "WDR19",
        "hgnc": "HGNC:18340",
        "name": "WD repeat domain 19",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/wdr19"
      },
      {
        "slug": "znf408",
        "symbol": "ZNF408",
        "hgnc": "HGNC:20041",
        "name": "zinc finger protein 408",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf408"
      },
      {
        "slug": "znf513",
        "symbol": "ZNF513",
        "hgnc": "HGNC:26498",
        "name": "zinc finger protein 513",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/znf513"
      },
      {
        "slug": "apc",
        "symbol": "APC",
        "hgnc": "HGNC:583",
        "name": "APC regulator of Wnt signaling pathway",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/apc"
      },
      {
        "slug": "cfh",
        "symbol": "CFH",
        "hgnc": "HGNC:4883",
        "name": "complement factor H",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfh"
      },
      {
        "slug": "cfi",
        "symbol": "CFI",
        "hgnc": "HGNC:5394",
        "name": "complement factor I",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cfi"
      },
      {
        "slug": "cox7b",
        "symbol": "COX7B",
        "hgnc": "HGNC:2291",
        "name": "cytochrome c oxidase subunit 7B",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cox7b"
      },
      {
        "slug": "cp",
        "symbol": "CP",
        "hgnc": "HGNC:2295",
        "name": "ceruloplasmin",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cp"
      },
      {
        "slug": "ctnnb1",
        "symbol": "CTNNB1",
        "hgnc": "HGNC:2514",
        "name": "catenin beta 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ctnnb1"
      },
      {
        "slug": "efemp1",
        "symbol": "EFEMP1",
        "hgnc": "HGNC:3218",
        "name": "EGF-like fibulin extracellular matrix protein 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/efemp1"
      },
      {
        "slug": "elmo2",
        "symbol": "ELMO2",
        "hgnc": "HGNC:17233",
        "name": "engulfment and cell motility 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/elmo2"
      },
      {
        "slug": "hccs",
        "symbol": "HCCS",
        "hgnc": "HGNC:4837",
        "name": "holocytochrome c synthase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hccs"
      },
      {
        "slug": "kif11",
        "symbol": "KIF11",
        "hgnc": "HGNC:6388",
        "name": "kinesin family member 11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kif11"
      },
      {
        "slug": "lyst",
        "symbol": "LYST",
        "hgnc": "HGNC:1968",
        "name": "lysosomal trafficking regulator",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lyst"
      },
      {
        "slug": "mc1r",
        "symbol": "MC1R",
        "hgnc": "HGNC:6929",
        "name": "melanocortin 1 receptor",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mc1r"
      },
      {
        "slug": "mttp",
        "symbol": "MTTP",
        "hgnc": "HGNC:7467",
        "name": "microsomal triglyceride transfer protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mttp"
      },
      {
        "slug": "ndufb11",
        "symbol": "NDUFB11",
        "hgnc": "HGNC:20372",
        "name": "NADH:ubiquinone oxidoreductase subunit B11",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ndufb11"
      },
      {
        "slug": "oca2",
        "symbol": "OCA2",
        "hgnc": "HGNC:8101",
        "name": "OCA2 melanosomal transmembrane protein",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/oca2"
      },
      {
        "slug": "pepd",
        "symbol": "PEPD",
        "hgnc": "HGNC:8840",
        "name": "peptidase D",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pepd"
      },
      {
        "slug": "pex1",
        "symbol": "PEX1",
        "hgnc": "HGNC:8850",
        "name": "peroxisomal biogenesis factor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex1"
      },
      {
        "slug": "pex10",
        "symbol": "PEX10",
        "hgnc": "HGNC:8851",
        "name": "peroxisomal biogenesis factor 10",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex10"
      },
      {
        "slug": "pex11b",
        "symbol": "PEX11B",
        "hgnc": "HGNC:8853",
        "name": "peroxisomal biogenesis factor 11 beta",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex11b"
      },
      {
        "slug": "pex12",
        "symbol": "PEX12",
        "hgnc": "HGNC:8854",
        "name": "peroxisomal biogenesis factor 12",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex12"
      },
      {
        "slug": "pex13",
        "symbol": "PEX13",
        "hgnc": "HGNC:8855",
        "name": "peroxisomal biogenesis factor 13",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex13"
      },
      {
        "slug": "pex14",
        "symbol": "PEX14",
        "hgnc": "HGNC:8856",
        "name": "peroxisomal biogenesis factor 14",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex14"
      },
      {
        "slug": "pex16",
        "symbol": "PEX16",
        "hgnc": "HGNC:8857",
        "name": "peroxisomal biogenesis factor 16",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex16"
      },
      {
        "slug": "pex19",
        "symbol": "PEX19",
        "hgnc": "HGNC:9713",
        "name": "peroxisomal biogenesis factor 19",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex19"
      },
      {
        "slug": "pex2",
        "symbol": "PEX2",
        "hgnc": "HGNC:9717",
        "name": "peroxisomal biogenesis factor 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex2"
      },
      {
        "slug": "pex26",
        "symbol": "PEX26",
        "hgnc": "HGNC:22965",
        "name": "peroxisomal biogenesis factor 26",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex26"
      },
      {
        "slug": "pex3",
        "symbol": "PEX3",
        "hgnc": "HGNC:8858",
        "name": "peroxisomal biogenesis factor 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex3"
      },
      {
        "slug": "pex5",
        "symbol": "PEX5",
        "hgnc": "HGNC:9719",
        "name": "peroxisomal biogenesis factor 5",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex5"
      },
      {
        "slug": "pex6",
        "symbol": "PEX6",
        "hgnc": "HGNC:8859",
        "name": "peroxisomal biogenesis factor 6",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pex6"
      },
      {
        "slug": "rab18",
        "symbol": "RAB18",
        "hgnc": "HGNC:14244",
        "name": "RAB18, member RAS oncogene family",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab18"
      },
      {
        "slug": "rab3gap1",
        "symbol": "RAB3GAP1",
        "hgnc": "HGNC:17063",
        "name": "RAB3 GTPase activating protein catalytic subunit 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab3gap1"
      },
      {
        "slug": "rab3gap2",
        "symbol": "RAB3GAP2",
        "hgnc": "HGNC:17168",
        "name": "RAB3 GTPase activating non-catalytic protein subunit 2",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rab3gap2"
      },
      {
        "slug": "rnu4atac",
        "symbol": "RNU4ATAC",
        "hgnc": "HGNC:34016",
        "name": "RNA, U4atac small nuclear",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnu4atac"
      },
      {
        "slug": "sumf1",
        "symbol": "SUMF1",
        "hgnc": "HGNC:20376",
        "name": "sulfatase modifying factor 1",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sumf1"
      },
      {
        "slug": "tbc1d20",
        "symbol": "TBC1D20",
        "hgnc": "HGNC:16133",
        "name": "TBC1 domain family member 20",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tbc1d20"
      },
      {
        "slug": "tnfrsf11a",
        "symbol": "TNFRSF11A",
        "hgnc": "HGNC:11908",
        "name": "TNF receptor superfamily member 11a",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf11a"
      },
      {
        "slug": "tnfrsf11b",
        "symbol": "TNFRSF11B",
        "hgnc": "HGNC:11909",
        "name": "TNF receptor superfamily member 11b",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tnfrsf11b"
      },
      {
        "slug": "wrn",
        "symbol": "WRN",
        "hgnc": "HGNC:12791",
        "name": "WRN RecQ like helicase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wrn"
      },
      {
        "slug": "akt1",
        "symbol": "AKT1",
        "hgnc": "HGNC:391",
        "name": "AKT serine/threonine kinase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/akt1"
      },
      {
        "slug": "aldh1a3",
        "symbol": "ALDH1A3",
        "hgnc": "HGNC:409",
        "name": "aldehyde dehydrogenase 1 family member A3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aldh1a3"
      },
      {
        "slug": "cbs",
        "symbol": "CBS",
        "hgnc": "HGNC:1550",
        "name": "cystathionine beta-synthase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cbs"
      },
      {
        "slug": "cep120",
        "symbol": "CEP120",
        "hgnc": "HGNC:26690",
        "name": "centrosomal protein 120",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/cep120"
      },
      {
        "slug": "dync2h1",
        "symbol": "DYNC2H1",
        "hgnc": "HGNC:2962",
        "name": "dynein cytoplasmic 2 heavy chain 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2h1"
      },
      {
        "slug": "dync2i1",
        "symbol": "DYNC2I1",
        "hgnc": "HGNC:21862",
        "name": "dynein 2 intermediate chain 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2i1"
      },
      {
        "slug": "dync2i2",
        "symbol": "DYNC2I2",
        "hgnc": "HGNC:28296",
        "name": "dynein 2 intermediate chain 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2i2"
      },
      {
        "slug": "dync2li1",
        "symbol": "DYNC2LI1",
        "hgnc": "HGNC:24595",
        "name": "dynein cytoplasmic 2 light intermediate chain 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dync2li1"
      },
      {
        "slug": "edn3",
        "symbol": "EDN3",
        "hgnc": "HGNC:3178",
        "name": "endothelin 3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/edn3"
      },
      {
        "slug": "ednrb",
        "symbol": "EDNRB",
        "hgnc": "HGNC:3180",
        "name": "endothelin receptor type B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ednrb"
      },
      {
        "slug": "ercc1",
        "symbol": "ERCC1",
        "hgnc": "HGNC:3433",
        "name": "ERCC excision repair 1, endonuclease non-catalytic subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc1"
      },
      {
        "slug": "ercc2",
        "symbol": "ERCC2",
        "hgnc": "HGNC:3434",
        "name": "ERCC excision repair 2, TFIIH core complex helicase subunit",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc2"
      },
      {
        "slug": "ercc5",
        "symbol": "ERCC5",
        "hgnc": "HGNC:3437",
        "name": "ERCC excision repair 5, endonuclease",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc5"
      },
      {
        "slug": "ercc6",
        "symbol": "ERCC6",
        "hgnc": "HGNC:3438",
        "name": "ERCC excision repair 6, chromatin remodeling factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ercc6"
      },
      {
        "slug": "hadha",
        "symbol": "HADHA",
        "hgnc": "HGNC:4801",
        "name": "hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hadha"
      },
      {
        "slug": "ift80",
        "symbol": "IFT80",
        "hgnc": "HGNC:29262",
        "name": "intraflagellar transport 80",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ift80"
      },
      {
        "slug": "kiaa0753",
        "symbol": "KIAA0753",
        "hgnc": "HGNC:29110",
        "name": "KIAA0753",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/kiaa0753"
      },
      {
        "slug": "mcoln1",
        "symbol": "MCOLN1",
        "hgnc": "HGNC:13356",
        "name": "mucolipin TRP cation channel 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mcoln1"
      },
      {
        "slug": "mfrp",
        "symbol": "MFRP",
        "hgnc": "HGNC:18121",
        "name": "membrane frizzled-related protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mfrp"
      },
      {
        "slug": "mitf",
        "symbol": "MITF",
        "hgnc": "HGNC:7105",
        "name": "melanocyte inducing transcription factor",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mitf"
      },
      {
        "slug": "morc2",
        "symbol": "MORC2",
        "hgnc": "HGNC:23573",
        "name": "MORC family CW-type zinc finger 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/morc2"
      },
      {
        "slug": "prss56",
        "symbol": "PRSS56",
        "hgnc": "HGNC:39433",
        "name": "serine protease 56",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/prss56"
      },
      {
        "slug": "rax",
        "symbol": "RAX",
        "hgnc": "HGNC:18662",
        "name": "retina and anterior neural fold homeobox",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rax"
      },
      {
        "slug": "rps6ka3",
        "symbol": "RPS6KA3",
        "hgnc": "HGNC:10432",
        "name": "ribosomal protein S6 kinase A3",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rps6ka3"
      },
      {
        "slug": "six6",
        "symbol": "SIX6",
        "hgnc": "HGNC:10892",
        "name": "SIX homeobox 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/six6"
      },
      {
        "slug": "slc12a6",
        "symbol": "SLC12A6",
        "hgnc": "HGNC:10914",
        "name": "solute carrier family 12 member 6",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc12a6"
      },
      {
        "slug": "sox10",
        "symbol": "SOX10",
        "hgnc": "HGNC:11190",
        "name": "SRY-box transcription factor 10",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox10"
      },
      {
        "slug": "sox2",
        "symbol": "SOX2",
        "hgnc": "HGNC:11195",
        "name": "SRY-box transcription factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sox2"
      },
      {
        "slug": "taf2",
        "symbol": "TAF2",
        "hgnc": "HGNC:11536",
        "name": "TATA-box binding protein associated factor 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/taf2"
      },
      {
        "slug": "tmem98",
        "symbol": "TMEM98",
        "hgnc": "HGNC:24529",
        "name": "transmembrane protein 98",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tmem98"
      },
      {
        "slug": "ttc21b",
        "symbol": "TTC21B",
        "hgnc": "HGNC:25660",
        "name": "tetratricopeptide repeat domain 21B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttc21b"
      },
      {
        "slug": "ttpa",
        "symbol": "TTPA",
        "hgnc": "HGNC:12404",
        "name": "alpha tocopherol transfer protein",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ttpa"
      },
      {
        "slug": "vps13b",
        "symbol": "VPS13B",
        "hgnc": "HGNC:2183",
        "name": "vacuolar protein sorting 13 homolog B",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps13b"
      },
      {
        "slug": "vps33a",
        "symbol": "VPS33A",
        "hgnc": "HGNC:18179",
        "name": "VPS33A core subunit of CORVET and HOPS complexes",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps33a"
      },
      {
        "slug": "flnb",
        "symbol": "FLNB",
        "hgnc": "HGNC:3755",
        "name": "filamin B",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flnb"
      },
      {
        "slug": "ids",
        "symbol": "IDS",
        "hgnc": "HGNC:5389",
        "name": "iduronate 2-sulfatase",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ids"
      },
      {
        "slug": "piezo2",
        "symbol": "PIEZO2",
        "hgnc": "HGNC:26270",
        "name": "piezo type mechanosensitive ion channel component 2",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piezo2"
      }
    ]
  }
}