{
  "url": "https://dantelabs.com/traits/abnormal-placenta-morphology",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-placenta-morphology",
    "id": "HP:0100767",
    "name": "Placental issue",
    "label": "Abnormal placenta morphology",
    "definition": "An abnormality of the placenta, the organ that connects the developing fetus to the uterine wall to enable nutrient uptake, waste elimination, and gas exchange.",
    "synonyms": [
      "Abnormality of the placenta"
    ],
    "systems": [
      {
        "slug": "abnormality-of-prenatal-development-or-birth",
        "name": "Abnormality of prenatal development or birth",
        "url": "https://dantelabs.com/traits/abnormality-of-prenatal-development-or-birth"
      }
    ],
    "broader": [
      {
        "slug": "abnormalities-of-placenta-or-umbilical-cord",
        "name": "Abnormalities of placenta or umbilical cord",
        "url": "https://dantelabs.com/traits/abnormalities-of-placenta-or-umbilical-cord"
      }
    ],
    "narrower": [
      {
        "slug": "choriocarcinoma",
        "name": "Choriocarcinoma",
        "genes": 8,
        "url": "https://dantelabs.com/traits/choriocarcinoma"
      },
      {
        "slug": "placental-abruption",
        "name": "Placental abruption",
        "genes": 6,
        "url": "https://dantelabs.com/traits/placental-abruption"
      },
      {
        "slug": "placental-mesenchymal-dysplasia",
        "name": "Placental mesenchymal dysplasia",
        "genes": 4,
        "url": "https://dantelabs.com/traits/placental-mesenchymal-dysplasia"
      },
      {
        "slug": "placenta-previa",
        "name": "Placenta previa",
        "genes": 2,
        "url": "https://dantelabs.com/traits/placenta-previa"
      },
      {
        "slug": "calcified-placenta",
        "name": "Calcified placenta",
        "genes": 1,
        "url": "https://dantelabs.com/traits/calcified-placenta"
      },
      {
        "slug": "abnormal-placental-size",
        "name": "Abnormal placental size",
        "genes": 0,
        "url": "https://dantelabs.com/traits/abnormal-placental-size"
      }
    ],
    "genes": [
      {
        "slug": "corin",
        "symbol": "CORIN",
        "hgnc": "HGNC:19012",
        "name": "corin, serine peptidase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/corin"
      },
      {
        "slug": "flt1",
        "symbol": "FLT1",
        "hgnc": "HGNC:3763",
        "name": "fms related receptor tyrosine kinase 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/flt1"
      },
      {
        "slug": "stox1",
        "symbol": "STOX1",
        "hgnc": "HGNC:23508",
        "name": "storkhead box 1",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/stox1"
      },
      {
        "slug": "glb1",
        "symbol": "GLB1",
        "hgnc": "HGNC:4298",
        "name": "galactosidase beta 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/glb1"
      },
      {
        "slug": "hymai",
        "symbol": "HYMAI",
        "hgnc": "HGNC:5326",
        "name": "hydatidiform mole associated and imprinted",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/hymai"
      },
      {
        "slug": "plagl1",
        "symbol": "PLAGL1",
        "hgnc": "HGNC:9046",
        "name": "PLAG1 like zinc finger 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/plagl1"
      },
      {
        "slug": "sptbn1",
        "symbol": "SPTBN1",
        "hgnc": "HGNC:11275",
        "name": "spectrin beta, non-erythrocytic 1",
        "frequency": "very-rare",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/sptbn1"
      }
    ]
  }
}