{
  "url": "https://dantelabs.com/traits/abnormal-ciliary-motility",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "abnormal-ciliary-motility",
    "id": "HP:0012262",
    "name": "Abnormal ciliary motility",
    "definition": "Any anomaly of the normal motility of motile cilia. Evaluation of ciliary beat frequency and ciliary beat pattern requires high-speed videomicroscopy of freshly obtained ciliary biopsies that are maintained in culture media under controlled conditions.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-respiratory-system",
        "name": "Abnormality of the respiratory system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-respiratory-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-respiratory-motile-cilium-physiology",
        "name": "Abnormal respiratory motile cilium physiology",
        "url": "https://dantelabs.com/traits/abnormal-respiratory-motile-cilium-physiology"
      }
    ],
    "narrower": [
      {
        "slug": "ciliary-dyskinesia",
        "name": "Ciliary dyskinesia",
        "genes": 32,
        "url": "https://dantelabs.com/traits/ciliary-dyskinesia"
      },
      {
        "slug": "immotile-cilia",
        "name": "Immotile cilia",
        "genes": 13,
        "url": "https://dantelabs.com/traits/immotile-cilia"
      }
    ],
    "genes": [
      {
        "slug": "dnah11",
        "symbol": "DNAH11",
        "hgnc": "HGNC:2942",
        "name": "dynein axonemal heavy chain 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnah11"
      },
      {
        "slug": "dnal1",
        "symbol": "DNAL1",
        "hgnc": "HGNC:23247",
        "name": "dynein axonemal light chain 1",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/dnal1"
      },
      {
        "slug": "ccdc39",
        "symbol": "CCDC39",
        "hgnc": "HGNC:25244",
        "name": "coiled-coil domain 39 molecular ruler complex subunit",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc39"
      },
      {
        "slug": "nme8",
        "symbol": "NME8",
        "hgnc": "HGNC:16473",
        "name": "NME/NM23 family member 8",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/nme8"
      }
    ]
  }
}