{
  "url": "https://dantelabs.com/et/genes/mei1",
  "gene": {
    "slug": "mei1",
    "symbol": "MEI1",
    "name": "meiotic double-stranded break formation protein 1",
    "hgnc": "HGNC:28613",
    "summary": null,
    "location": "22q13.2",
    "locusType": "gene with protein product",
    "aliases": [
      "MGC40042",
      "SPATA38"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000167077",
    "entrezId": 150365,
    "omim": [
      "608797"
    ],
    "uniprot": [
      "Q5TIA1"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "22",
      "start": 41699503,
      "end": 41799454,
      "strand": "+",
      "ensemblTranscript": "ENST00000401548.8",
      "refseqTranscript": "NM_152513.4",
      "ensemblProtein": "ENSP00000384115.3",
      "refseqProtein": "NP_689726.3",
      "exons": [
        {
          "start": 41699503,
          "end": 41699712
        },
        {
          "start": 41703331,
          "end": 41703454
        },
        {
          "start": 41705504,
          "end": 41705554
        },
        {
          "start": 41714002,
          "end": 41714075
        },
        {
          "start": 41716041,
          "end": 41716146
        },
        {
          "start": 41718071,
          "end": 41718274
        },
        {
          "start": 41723943,
          "end": 41724073
        },
        {
          "start": 41729665,
          "end": 41729779
        },
        {
          "start": 41730521,
          "end": 41730637
        },
        {
          "start": 41732245,
          "end": 41732344
        },
        {
          "start": 41732469,
          "end": 41732603
        },
        {
          "start": 41743080,
          "end": 41743194
        },
        {
          "start": 41744973,
          "end": 41745064
        },
        {
          "start": 41745885,
          "end": 41746026
        },
        {
          "start": 41748107,
          "end": 41748218
        },
        {
          "start": 41752591,
          "end": 41752651
        },
        {
          "start": 41753949,
          "end": 41754046
        },
        {
          "start": 41758365,
          "end": 41758533
        },
        {
          "start": 41763174,
          "end": 41763321
        },
        {
          "start": 41770686,
          "end": 41770961
        },
        {
          "start": 41776102,
          "end": 41776267
        },
        {
          "start": 41778708,
          "end": 41778812
        },
        {
          "start": 41781284,
          "end": 41781394
        },
        {
          "start": 41781685,
          "end": 41781845
        },
        {
          "start": 41784339,
          "end": 41784420
        },
        {
          "start": 41784608,
          "end": 41784783
        },
        {
          "start": 41793829,
          "end": 41793910
        },
        {
          "start": 41794371,
          "end": 41794477
        },
        {
          "start": 41795411,
          "end": 41795542
        },
        {
          "start": 41795735,
          "end": 41795847
        },
        {
          "start": 41799254,
          "end": 41799454
        }
      ],
      "cds": {
        "start": 41699539,
        "end": 41799299
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "22",
      "start": 42095503,
      "end": 42195460,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 41249479,
      "end": 42249478,
      "genes": [
        {
          "symbol": "RANGAP1",
          "ensemblId": "ENSG00000100401",
          "biotype": "protein_coding",
          "start": 41243474,
          "end": 41302744,
          "strand": "-",
          "slug": "rangap1"
        },
        {
          "symbol": "ZC3H7B",
          "ensemblId": "ENSG00000100403",
          "biotype": "protein_coding",
          "start": 41301457,
          "end": 41360155,
          "strand": "+",
          "slug": "zc3h7b"
        },
        {
          "symbol": "TEF",
          "ensemblId": "ENSG00000167074",
          "biotype": "protein_coding",
          "start": 41367333,
          "end": 41399326,
          "strand": "+",
          "slug": "tef"
        },
        {
          "symbol": "TOB2",
          "ensemblId": "ENSG00000183864",
          "biotype": "protein_coding",
          "start": 41433489,
          "end": 41447602,
          "strand": "-",
          "slug": "tob2"
        },
        {
          "symbol": "ACO2",
          "ensemblId": "ENSG00000100412",
          "biotype": "protein_coding",
          "start": 41447830,
          "end": 41529273,
          "strand": "+",
          "slug": "aco2"
        },
        {
          "symbol": "PHF5A",
          "ensemblId": "ENSG00000100410",
          "biotype": "protein_coding",
          "start": 41448895,
          "end": 41468713,
          "strand": "-",
          "slug": "phf5a"
        },
        {
          "symbol": "POLR3H",
          "ensemblId": "ENSG00000100413",
          "biotype": "protein_coding",
          "start": 41525799,
          "end": 41544606,
          "strand": "-",
          "slug": "polr3h"
        },
        {
          "symbol": "CSDC2",
          "ensemblId": "ENSG00000172346",
          "biotype": "protein_coding",
          "start": 41560758,
          "end": 41577741,
          "strand": "+",
          "slug": "csdc2"
        },
        {
          "symbol": "PMM1",
          "ensemblId": "ENSG00000100417",
          "biotype": "protein_coding",
          "start": 41576886,
          "end": 41595275,
          "strand": "-",
          "slug": "pmm1"
        },
        {
          "symbol": "DESI1",
          "ensemblId": "ENSG00000100418",
          "biotype": "protein_coding",
          "start": 41598028,
          "end": 41621089,
          "strand": "-",
          "slug": "desi1"
        },
        {
          "symbol": "XRCC6",
          "ensemblId": "ENSG00000196419",
          "biotype": "protein_coding",
          "start": 41620786,
          "end": 41664087,
          "strand": "+",
          "slug": "xrcc6"
        },
        {
          "symbol": "SNU13",
          "ensemblId": "ENSG00000100138",
          "biotype": "protein_coding",
          "start": 41666627,
          "end": 41690504,
          "strand": "-",
          "slug": "snu13"
        },
        {
          "symbol": "CCDC134",
          "ensemblId": "ENSG00000100147",
          "biotype": "protein_coding",
          "start": 41800321,
          "end": 41832178,
          "strand": "+",
          "slug": "ccdc134"
        },
        {
          "symbol": "SREBF2",
          "ensemblId": "ENSG00000198911",
          "biotype": "protein_coding",
          "start": 41833029,
          "end": 41907308,
          "strand": "+",
          "slug": "srebf2"
        },
        {
          "symbol": "SHISA8",
          "ensemblId": "ENSG00000234965",
          "biotype": "protein_coding",
          "start": 41906316,
          "end": 41915129,
          "strand": "-",
          "slug": "shisa8"
        },
        {
          "symbol": "TNFRSF13C",
          "ensemblId": "ENSG00000159958",
          "biotype": "protein_coding",
          "start": 41922032,
          "end": 41926806,
          "strand": "-",
          "slug": "tnfrsf13c"
        },
        {
          "symbol": "CENPM",
          "ensemblId": "ENSG00000100162",
          "biotype": "protein_coding",
          "start": 41927514,
          "end": 41947183,
          "strand": "-",
          "slug": "cenpm"
        },
        {
          "symbol": "SMIM45",
          "ensemblId": "ENSG00000205704",
          "biotype": "protein_coding",
          "start": 41947178,
          "end": 41958942,
          "strand": "+",
          "slug": "smim45"
        },
        {
          "symbol": "SEPTIN3",
          "ensemblId": "ENSG00000100167",
          "biotype": "protein_coding",
          "start": 41969443,
          "end": 41998221,
          "strand": "+",
          "slug": "septin3"
        },
        {
          "symbol": "WBP2NL",
          "ensemblId": "ENSG00000183066",
          "biotype": "protein_coding",
          "start": 41998725,
          "end": 42058456,
          "strand": "+",
          "slug": "wbp2nl"
        },
        {
          "symbol": "NAGA",
          "ensemblId": "ENSG00000198951",
          "biotype": "protein_coding",
          "start": 42032595,
          "end": 42071198,
          "strand": "-",
          "slug": "naga"
        },
        {
          "symbol": "PHETA2",
          "ensemblId": "ENSG00000177096",
          "biotype": "protein_coding",
          "start": 42073789,
          "end": 42079439,
          "strand": "+",
          "slug": "pheta2"
        },
        {
          "symbol": "SMDT1",
          "ensemblId": "ENSG00000183172",
          "biotype": "protein_coding",
          "start": 42079564,
          "end": 42090033,
          "strand": "+",
          "slug": "smdt1"
        },
        {
          "symbol": "NDUFA6",
          "ensemblId": "ENSG00000184983",
          "biotype": "protein_coding",
          "start": 42080336,
          "end": 42090884,
          "strand": "-",
          "slug": "ndufa6"
        },
        {
          "symbol": "CYP2D6",
          "ensemblId": "ENSG00000100197",
          "biotype": "protein_coding",
          "start": 42120962,
          "end": 42131727,
          "strand": "-",
          "slug": "cyp2d6"
        },
        {
          "symbol": "CYP2D7",
          "ensemblId": "ENSG00000205702",
          "biotype": "protein_coding",
          "start": 42140203,
          "end": 42149500,
          "strand": "-",
          "slug": "cyp2d7"
        },
        {
          "symbol": "TCF20",
          "ensemblId": "ENSG00000100207",
          "biotype": "protein_coding",
          "start": 42160013,
          "end": 42343616,
          "strand": "-",
          "slug": "tcf20"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "female-infertility",
        "name": "Female infertility",
        "systems": [
          "abnormality-of-the-genitourinary-system"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/female-infertility"
      },
      {
        "slug": "hydatidiform-mole",
        "name": "Hydatidiform mole",
        "systems": [
          "abnormality-of-prenatal-development-or-birth"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/hydatidiform-mole"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}