{
  "url": "https://dantelabs.com/et/genes/idh3g",
  "gene": {
    "slug": "idh3g",
    "symbol": "IDH3G",
    "name": "isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma",
    "hgnc": "HGNC:5386",
    "summary": null,
    "location": "Xq28",
    "locusType": "gene with protein product",
    "aliases": [],
    "previousSymbols": [],
    "ensemblId": "ENSG00000067829",
    "entrezId": 3421,
    "omim": [
      "300089"
    ],
    "uniprot": [
      "P51553"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "X",
      "start": 153785768,
      "end": 153794375,
      "strand": "-",
      "ensemblTranscript": "ENST00000217901.10",
      "refseqTranscript": "NM_004135.4",
      "ensemblProtein": "ENSP00000217901.5",
      "refseqProtein": "NP_004126.1",
      "exons": [
        {
          "start": 153785768,
          "end": 153785973
        },
        {
          "start": 153786212,
          "end": 153786272
        },
        {
          "start": 153786355,
          "end": 153786449
        },
        {
          "start": 153786801,
          "end": 153786947
        },
        {
          "start": 153787051,
          "end": 153787153
        },
        {
          "start": 153787464,
          "end": 153787597
        },
        {
          "start": 153787823,
          "end": 153787955
        },
        {
          "start": 153788075,
          "end": 153788135
        },
        {
          "start": 153789712,
          "end": 153789824
        },
        {
          "start": 153790195,
          "end": 153790292
        },
        {
          "start": 153790564,
          "end": 153790575
        },
        {
          "start": 153790810,
          "end": 153790851
        },
        {
          "start": 153794246,
          "end": 153794375
        }
      ],
      "cds": {
        "start": 153785872,
        "end": 153794326
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "X",
      "start": 153051221,
      "end": 153059978,
      "strand": "-"
    },
    "neighbourhood": {
      "release": "116",
      "start": 153290072,
      "end": 154290071,
      "genes": [
        {
          "symbol": "PNMA6F",
          "ensemblId": "ENSG00000225110",
          "biotype": "protein_coding",
          "start": 153317680,
          "end": 153321774,
          "strand": "-",
          "slug": "pnma6f"
        },
        {
          "symbol": "ZNF275",
          "ensemblId": "ENSG00000063587",
          "biotype": "protein_coding",
          "start": 153334122,
          "end": 153360110,
          "strand": "+",
          "slug": "znf275"
        },
        {
          "symbol": "PNMA6E",
          "ensemblId": "ENSG00000214897",
          "biotype": "protein_coding",
          "start": 153395639,
          "end": 153401392,
          "strand": "-",
          "slug": "pnma6e"
        },
        {
          "symbol": "ZFP92",
          "ensemblId": "ENSG00000189420",
          "biotype": "protein_coding",
          "start": 153411434,
          "end": 153426481,
          "strand": "+",
          "slug": "zfp92"
        },
        {
          "symbol": "TREX2",
          "ensemblId": "ENSG00000183479",
          "biotype": "protein_coding",
          "start": 153444473,
          "end": 153470592,
          "strand": "-",
          "slug": "trex2"
        },
        {
          "symbol": "HAUS7",
          "ensemblId": "ENSG00000213397",
          "biotype": "protein_coding",
          "start": 153447655,
          "end": 153495529,
          "strand": "-",
          "slug": "haus7"
        },
        {
          "symbol": "BGN",
          "ensemblId": "ENSG00000182492",
          "biotype": "protein_coding",
          "start": 153488654,
          "end": 153510711,
          "strand": "+",
          "slug": "bgn"
        },
        {
          "symbol": "ATP2B3",
          "ensemblId": "ENSG00000067842",
          "biotype": "protein_coding",
          "start": 153517620,
          "end": 153582939,
          "strand": "+",
          "slug": "atp2b3"
        },
        {
          "symbol": "CCNQ",
          "ensemblId": "ENSG00000262919",
          "biotype": "protein_coding",
          "start": 153587925,
          "end": 153600045,
          "strand": "-",
          "slug": "ccnq"
        },
        {
          "symbol": "DUSP9",
          "ensemblId": "ENSG00000130829",
          "biotype": "protein_coding",
          "start": 153642397,
          "end": 153651326,
          "strand": "+",
          "slug": "dusp9"
        },
        {
          "symbol": "PNCK",
          "ensemblId": "ENSG00000130822",
          "biotype": "protein_coding",
          "start": 153669730,
          "end": 153689033,
          "strand": "-",
          "slug": "pnck"
        },
        {
          "symbol": "SLC6A8",
          "ensemblId": "ENSG00000130821",
          "biotype": "protein_coding",
          "start": 153687914,
          "end": 153696591,
          "strand": "+",
          "slug": "slc6a8"
        },
        {
          "symbol": "BCAP31",
          "ensemblId": "ENSG00000185825",
          "biotype": "protein_coding",
          "start": 153698006,
          "end": 153725957,
          "strand": "-",
          "slug": "bcap31"
        },
        {
          "symbol": "ABCD1",
          "ensemblId": "ENSG00000101986",
          "biotype": "protein_coding",
          "start": 153724495,
          "end": 153744755,
          "strand": "+",
          "slug": "abcd1"
        },
        {
          "symbol": "PLXNB3",
          "ensemblId": "ENSG00000198753",
          "biotype": "protein_coding",
          "start": 153764179,
          "end": 153779346,
          "strand": "+",
          "slug": "plxnb3"
        },
        {
          "symbol": "SRPK3",
          "ensemblId": "ENSG00000184343",
          "biotype": "protein_coding",
          "start": 153781001,
          "end": 153785768,
          "strand": "+",
          "slug": "srpk3"
        },
        {
          "symbol": "SSR4",
          "ensemblId": "ENSG00000180879",
          "biotype": "protein_coding",
          "start": 153793516,
          "end": 153798510,
          "strand": "+",
          "slug": "ssr4"
        },
        {
          "symbol": "PDZD4",
          "ensemblId": "ENSG00000067840",
          "biotype": "protein_coding",
          "start": 153802161,
          "end": 153830935,
          "strand": "-",
          "slug": "pdzd4"
        },
        {
          "symbol": "L1CAM",
          "ensemblId": "ENSG00000198910",
          "biotype": "protein_coding",
          "start": 153861511,
          "end": 153886204,
          "strand": "-",
          "slug": "l1cam"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000284987",
          "biotype": "protein_coding",
          "start": 153872221,
          "end": 153909223,
          "strand": "-"
        },
        {
          "symbol": "AVPR2",
          "ensemblId": "ENSG00000126895",
          "biotype": "protein_coding",
          "start": 153902531,
          "end": 153907169,
          "strand": "+",
          "slug": "avpr2"
        },
        {
          "symbol": "ARHGAP4",
          "ensemblId": "ENSG00000089820",
          "biotype": "protein_coding",
          "start": 153907367,
          "end": 153934999,
          "strand": "-",
          "slug": "arhgap4"
        },
        {
          "symbol": "NAA10",
          "ensemblId": "ENSG00000102030",
          "biotype": "protein_coding",
          "start": 153928799,
          "end": 153935083,
          "strand": "-",
          "slug": "naa10"
        },
        {
          "symbol": "RENBP",
          "ensemblId": "ENSG00000102032",
          "biotype": "protein_coding",
          "start": 153935269,
          "end": 153944688,
          "strand": "-",
          "slug": "renbp"
        },
        {
          "symbol": "HCFC1",
          "ensemblId": "ENSG00000172534",
          "biotype": "protein_coding",
          "start": 153946434,
          "end": 153972427,
          "strand": "-",
          "slug": "hcfc1"
        },
        {
          "symbol": "TMEM187",
          "ensemblId": "ENSG00000177854",
          "biotype": "protein_coding",
          "start": 153972290,
          "end": 153983194,
          "strand": "+",
          "slug": "tmem187"
        },
        {
          "symbol": "IRAK1",
          "ensemblId": "ENSG00000184216",
          "biotype": "protein_coding",
          "start": 154010501,
          "end": 154020650,
          "strand": "-",
          "slug": "irak1"
        },
        {
          "symbol": "MECP2",
          "ensemblId": "ENSG00000169057",
          "biotype": "protein_coding",
          "start": 154021573,
          "end": 154137103,
          "strand": "-",
          "slug": "mecp2"
        },
        {
          "symbol": "OPN1LW",
          "ensemblId": "ENSG00000102076",
          "biotype": "protein_coding",
          "start": 154144243,
          "end": 154159032,
          "strand": "+",
          "slug": "opn1lw"
        },
        {
          "symbol": "OPN1MW",
          "ensemblId": "ENSG00000268221",
          "biotype": "protein_coding",
          "start": 154182596,
          "end": 154196861,
          "strand": "+",
          "slug": "opn1mw"
        },
        {
          "symbol": "OPN1MW2",
          "ensemblId": "ENSG00000166160",
          "biotype": "protein_coding",
          "start": 154219756,
          "end": 154233286,
          "strand": "+",
          "slug": "opn1mw2"
        },
        {
          "symbol": "OPN1MW3",
          "ensemblId": "ENSG00000269433",
          "biotype": "protein_coding",
          "start": 154257582,
          "end": 154271090,
          "strand": "+",
          "slug": "opn1mw3"
        },
        {
          "symbol": "TEX28",
          "ensemblId": "ENSG00000278057",
          "biotype": "protein_coding",
          "start": 154271265,
          "end": 154295853,
          "strand": "-",
          "slug": "tex28"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [
      {
        "slug": "nyctalopia",
        "name": "Difficulties with night vision",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/nyctalopia"
      },
      {
        "slug": "dull-foveal-reflex",
        "name": "Dull foveal reflex",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/dull-foveal-reflex"
      },
      {
        "slug": "focal-retinal-arteriolar-constriction",
        "name": "Focal retinal arteriolar constriction",
        "systems": [
          "abnormality-of-head-or-neck",
          "abnormality-of-the-cardiovascular-system",
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/focal-retinal-arteriolar-constriction"
      },
      {
        "slug": "hypoautofluorescent-retinal-lesion",
        "name": "Hypoautofluorescent retinal lesion",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/hypoautofluorescent-retinal-lesion"
      },
      {
        "slug": "constriction-of-peripheral-visual-field",
        "name": "Limited peripheral vision",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "very-frequent",
        "url": "https://dantelabs.com/traits/constriction-of-peripheral-visual-field"
      },
      {
        "slug": "mildly-reduced-visual-acuity",
        "name": "Mildly reduced visual acuity",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "frequent",
        "url": "https://dantelabs.com/traits/mildly-reduced-visual-acuity"
      },
      {
        "slug": "optic-disc-pallor",
        "name": "Optic disc pallor",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/optic-disc-pallor"
      },
      {
        "slug": "perifoveal-ring-of-hyperautofluorescence",
        "name": "Perifoveal ring of hyperautofluorescence",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/perifoveal-ring-of-hyperautofluorescence"
      },
      {
        "slug": "retinal-pigment-epithelial-atrophy",
        "name": "Retinal pigment epithelial atrophy",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/retinal-pigment-epithelial-atrophy"
      },
      {
        "slug": "ring-scotoma",
        "name": "Ring scotoma",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "occasional",
        "url": "https://dantelabs.com/traits/ring-scotoma"
      },
      {
        "slug": "spicular-pigmentation-of-the-retina",
        "name": "Spicular pigmentation of the retina",
        "systems": [
          "abnormality-of-the-eye"
        ],
        "frequency": "obligate",
        "url": "https://dantelabs.com/traits/spicular-pigmentation-of-the-retina"
      }
    ],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}