{
  "url": "https://dantelabs.com/et/genes/hecw1",
  "gene": {
    "slug": "hecw1",
    "symbol": "HECW1",
    "name": "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1",
    "hgnc": "HGNC:22195",
    "summary": null,
    "location": "7p14.1-p13",
    "locusType": "gene with protein product",
    "aliases": [
      "KIAA0322",
      "NEDL1"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000002746",
    "entrezId": 23072,
    "omim": [
      "610384"
    ],
    "uniprot": [
      "Q76N89"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "7",
      "start": 43112647,
      "end": 43566001,
      "strand": "+",
      "ensemblTranscript": "ENST00000395891.7",
      "refseqTranscript": "NM_015052.5",
      "ensemblProtein": "ENSP00000379228.1",
      "refseqProtein": "NP_055867.3",
      "exons": [
        {
          "start": 43112647,
          "end": 43112937
        },
        {
          "start": 43114157,
          "end": 43114391
        },
        {
          "start": 43243875,
          "end": 43243932
        },
        {
          "start": 43311763,
          "end": 43312087
        },
        {
          "start": 43320635,
          "end": 43320742
        },
        {
          "start": 43360886,
          "end": 43360980
        },
        {
          "start": 43396814,
          "end": 43396889
        },
        {
          "start": 43407562,
          "end": 43407731
        },
        {
          "start": 43438003,
          "end": 43438145
        },
        {
          "start": 43442529,
          "end": 43442629
        },
        {
          "start": 43444218,
          "end": 43445570
        },
        {
          "start": 43450828,
          "end": 43450929
        },
        {
          "start": 43456297,
          "end": 43456447
        },
        {
          "start": 43463660,
          "end": 43463799
        },
        {
          "start": 43466447,
          "end": 43466568
        },
        {
          "start": 43468920,
          "end": 43469105
        },
        {
          "start": 43479610,
          "end": 43479744
        },
        {
          "start": 43492075,
          "end": 43492180
        },
        {
          "start": 43493084,
          "end": 43493180
        },
        {
          "start": 43500699,
          "end": 43500782
        },
        {
          "start": 43501213,
          "end": 43501322
        },
        {
          "start": 43507137,
          "end": 43507257
        },
        {
          "start": 43508018,
          "end": 43508131
        },
        {
          "start": 43508969,
          "end": 43509121
        },
        {
          "start": 43541163,
          "end": 43541261
        },
        {
          "start": 43541869,
          "end": 43541998
        },
        {
          "start": 43550445,
          "end": 43550591
        },
        {
          "start": 43552222,
          "end": 43552336
        },
        {
          "start": 43554592,
          "end": 43554790
        },
        {
          "start": 43561815,
          "end": 43566001
        }
      ],
      "cds": {
        "start": 43243906,
        "end": 43561926
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "7",
      "start": 43152198,
      "end": 43605600,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 42659292,
      "end": 44019356,
      "genes": [
        {
          "symbol": "C7orf25",
          "ensemblId": "ENSG00000136197",
          "biotype": "protein_coding",
          "start": 42883178,
          "end": 42912518,
          "strand": "-",
          "slug": "c7orf25"
        },
        {
          "symbol": "",
          "ensemblId": "ENSG00000256646",
          "biotype": "protein_coding",
          "start": 42909273,
          "end": 42932214,
          "strand": "-"
        },
        {
          "symbol": "PSMA2",
          "ensemblId": "ENSG00000106588",
          "biotype": "protein_coding",
          "start": 42916828,
          "end": 42932223,
          "strand": "-",
          "slug": "psma2"
        },
        {
          "symbol": "MRPL32",
          "ensemblId": "ENSG00000106591",
          "biotype": "protein_coding",
          "start": 42932346,
          "end": 42948958,
          "strand": "+",
          "slug": "mrpl32"
        },
        {
          "symbol": "COA1",
          "ensemblId": "ENSG00000106603",
          "biotype": "protein_coding",
          "start": 43552389,
          "end": 43729857,
          "strand": "-",
          "slug": "coa1"
        },
        {
          "symbol": "STK17A",
          "ensemblId": "ENSG00000164543",
          "biotype": "protein_coding",
          "start": 43582758,
          "end": 43650713,
          "strand": "+",
          "slug": "stk17a"
        },
        {
          "symbol": "BLVRA",
          "ensemblId": "ENSG00000106605",
          "biotype": "protein_coding",
          "start": 43758009,
          "end": 43808868,
          "strand": "+",
          "slug": "blvra"
        },
        {
          "symbol": "MRPS24",
          "ensemblId": "ENSG00000062582",
          "biotype": "protein_coding",
          "start": 43866556,
          "end": 43869893,
          "strand": "-",
          "slug": "mrps24"
        },
        {
          "symbol": "URGCP-MRPS24",
          "ensemblId": "ENSG00000270617",
          "biotype": "protein_coding",
          "start": 43866558,
          "end": 43906589,
          "strand": "-",
          "slug": "urgcp-mrps24"
        },
        {
          "symbol": "URGCP",
          "ensemblId": "ENSG00000106608",
          "biotype": "protein_coding",
          "start": 43873645,
          "end": 43926411,
          "strand": "-",
          "slug": "urgcp"
        },
        {
          "symbol": "UBE2D4",
          "ensemblId": "ENSG00000078967",
          "biotype": "protein_coding",
          "start": 43925799,
          "end": 43956136,
          "strand": "+",
          "slug": "ube2d4"
        },
        {
          "symbol": "SPDYE1",
          "ensemblId": "ENSG00000136206",
          "biotype": "protein_coding",
          "start": 43997897,
          "end": 44010124,
          "strand": "+",
          "slug": "spdye1"
        }
      ],
      "truncated": false
    },
    "reports": [],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [],
    "sources": null,
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}