{
  "url": "https://dantelabs.com/et/genes/cybrd1",
  "gene": {
    "slug": "cybrd1",
    "symbol": "CYBRD1",
    "name": "cytochrome b reductase 1",
    "hgnc": "HGNC:20797",
    "summary": null,
    "location": "2q31.1",
    "locusType": "gene with protein product",
    "aliases": [
      "DCYTB",
      "FLJ23462",
      "FRRS3",
      "CYB561A2"
    ],
    "previousSymbols": [],
    "ensemblId": "ENSG00000071967",
    "entrezId": 79901,
    "omim": [
      "605745"
    ],
    "uniprot": [
      "Q53TN4"
    ],
    "model": {
      "build": "GRCh38",
      "release": "v1.5",
      "chrom": "2",
      "start": 171522474,
      "end": 171558129,
      "strand": "+",
      "ensemblTranscript": "ENST00000321348.9",
      "refseqTranscript": "NM_024843.4",
      "ensemblProtein": "ENSP00000319141.4",
      "refseqProtein": "NP_079119.3",
      "exons": [
        {
          "start": 171522474,
          "end": 171522738
        },
        {
          "start": 171541585,
          "end": 171541793
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        {
          "start": 171553346,
          "end": 171553500
        },
        {
          "start": 171554524,
          "end": 171558129
        }
      ],
      "cds": {
        "start": 171522546,
        "end": 171554827
      }
    },
    "grch37": {
      "build": "GRCh37",
      "release": "87",
      "chrom": "2",
      "start": 172378757,
      "end": 172414643,
      "strand": "+"
    },
    "neighbourhood": {
      "release": "116",
      "start": 171040302,
      "end": 172040301,
      "genes": [
        {
          "symbol": "TLK1",
          "ensemblId": "ENSG00000198586",
          "biotype": "protein_coding",
          "start": 170990823,
          "end": 171231314,
          "strand": "-",
          "slug": "tlk1"
        },
        {
          "symbol": "METTL8",
          "ensemblId": "ENSG00000123600",
          "biotype": "protein_coding",
          "start": 171315746,
          "end": 171434802,
          "strand": "-",
          "slug": "mettl8"
        },
        {
          "symbol": "DCAF17",
          "ensemblId": "ENSG00000115827",
          "biotype": "protein_coding",
          "start": 171434217,
          "end": 171491318,
          "strand": "+",
          "slug": "dcaf17"
        },
        {
          "symbol": "DYNC1I2",
          "ensemblId": "ENSG00000077380",
          "biotype": "protein_coding",
          "start": 171687409,
          "end": 171750179,
          "strand": "+",
          "slug": "dync1i2"
        },
        {
          "symbol": "SLC25A12",
          "ensemblId": "ENSG00000115840",
          "biotype": "protein_coding",
          "start": 171781168,
          "end": 171999859,
          "strand": "-",
          "slug": "slc25a12"
        },
        {
          "symbol": "HAT1",
          "ensemblId": "ENSG00000128708",
          "biotype": "protein_coding",
          "start": 171922404,
          "end": 171986773,
          "strand": "+",
          "slug": "hat1"
        },
        {
          "symbol": "METAP1D",
          "ensemblId": "ENSG00000172878",
          "biotype": "protein_coding",
          "start": 171999935,
          "end": 172083989,
          "strand": "+",
          "slug": "metap1d"
        }
      ],
      "truncated": false
    },
    "reports": [
      {
        "slug": "hemochromatosis",
        "name": "Hemokromatoos",
        "diseases": [
          {
            "mondoId": "MONDO:0006507",
            "name": "Pärilik hemokromatoos",
            "genes": 6,
            "inheritance": null,
            "description": "Pärilik ainevahetushäire, mida iseloomustab raua kogunemine kudedesse.",
            "management": "Flebotoomia, raua kelaatravi, rauarikka toidu piiramine, sugulaste sõeluuring",
            "evidence": {
              "gencc": [
                "Genomics England PanelApp"
              ],
              "acmgSf": false,
              "inheritance": [
                "autosomal-recessive"
              ]
            },
            "sameAsReport": false,
            "broad": false
          }
        ],
        "url": "https://dantelabs.com/et/conditions/hemochromatosis"
      }
    ],
    "pharmacogenomics": [],
    "traits": [],
    "phenotypes": [],
    "related": [
      {
        "slug": "hamp",
        "symbol": "HAMP",
        "name": "hepcidin antimicrobial peptide",
        "shared": 1,
        "url": "https://dantelabs.com/et/genes/hamp"
      },
      {
        "slug": "hfe",
        "symbol": "HFE",
        "name": "homeostatic iron regulator",
        "shared": 1,
        "url": "https://dantelabs.com/et/genes/hfe"
      },
      {
        "slug": "hjv",
        "symbol": "HJV",
        "name": "hemojuvelin BMP co-receptor",
        "shared": 1,
        "url": "https://dantelabs.com/et/genes/hjv"
      },
      {
        "slug": "slc40a1",
        "symbol": "SLC40A1",
        "name": "solute carrier family 40 member 1",
        "shared": 1,
        "url": "https://dantelabs.com/et/genes/slc40a1"
      },
      {
        "slug": "tfr2",
        "symbol": "TFR2",
        "name": "transferrin receptor 2",
        "shared": 1,
        "url": "https://dantelabs.com/et/genes/tfr2"
      }
    ],
    "sources": {
      "bundleId": "2026.10.17-8666dff2",
      "panel": "2026-10-17",
      "acmgSf": "SF v3.2"
    },
    "locusKind": "proteinCoding"
  },
  "variants": {
    "total": 0,
    "url": null,
    "items": []
  }
}