{
  "url": "https://dantelabs.com/traits/white-forelock",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "white-forelock",
    "id": "HP:0002211",
    "name": "White part of hair above forehead",
    "label": "White forelock",
    "definition": "A triangular depigmented region of white hairs located in the anterior midline of the scalp.",
    "synonyms": [
      "Poliosis of anterior hair",
      "Poliosis of forelock hair"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-integument",
        "name": "Abnormality of the integument",
        "url": "https://dantelabs.com/traits/abnormality-of-the-integument"
      }
    ],
    "broader": [
      {
        "slug": "patchy-hypopigmentation-of-hair",
        "name": "Patchy hypopigmentation of hair",
        "url": "https://dantelabs.com/traits/patchy-hypopigmentation-of-hair"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "sox10",
        "symbol": "SOX10",
        "hgnc": "HGNC:11190",
        "name": "SRY-box transcription factor 10",
        "frequency": "obligate",
        "diseases": 6,
        "url": "https://dantelabs.com/genes/sox10"
      },
      {
        "slug": "edn3",
        "symbol": "EDN3",
        "hgnc": "HGNC:3178",
        "name": "endothelin 3",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/edn3"
      },
      {
        "slug": "ednrb",
        "symbol": "EDNRB",
        "hgnc": "HGNC:3180",
        "name": "endothelin receptor type B",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/ednrb"
      },
      {
        "slug": "kit",
        "symbol": "KIT",
        "hgnc": "HGNC:6342",
        "name": "KIT proto-oncogene, receptor tyrosine kinase",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kit"
      },
      {
        "slug": "lmna",
        "symbol": "LMNA",
        "hgnc": "HGNC:6636",
        "name": "lamin A/C",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lmna"
      },
      {
        "slug": "mitf",
        "symbol": "MITF",
        "hgnc": "HGNC:7105",
        "name": "melanocyte inducing transcription factor",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/mitf"
      },
      {
        "slug": "pax3",
        "symbol": "PAX3",
        "hgnc": "HGNC:8617",
        "name": "paired box 3",
        "frequency": "very-frequent",
        "diseases": 3,
        "url": "https://dantelabs.com/genes/pax3"
      },
      {
        "slug": "snai2",
        "symbol": "SNAI2",
        "hgnc": "HGNC:11094",
        "name": "snail family transcriptional repressor 2",
        "frequency": "very-frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/snai2"
      },
      {
        "slug": "wrn",
        "symbol": "WRN",
        "hgnc": "HGNC:12791",
        "name": "WRN RecQ like helicase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/wrn"
      },
      {
        "slug": "kitlg",
        "symbol": "KITLG",
        "hgnc": "HGNC:6343",
        "name": "KIT ligand",
        "frequency": "frequent",
        "diseases": 2,
        "url": "https://dantelabs.com/genes/kitlg"
      },
      {
        "slug": "pepd",
        "symbol": "PEPD",
        "hgnc": "HGNC:8840",
        "name": "peptidase D",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pepd"
      },
      {
        "slug": "tert",
        "symbol": "TERT",
        "hgnc": "HGNC:11730",
        "name": "telomerase reverse transcriptase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tert"
      },
      {
        "slug": "tyr",
        "symbol": "TYR",
        "hgnc": "HGNC:12442",
        "name": "tyrosinase",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tyr"
      },
      {
        "slug": "tfap2a",
        "symbol": "TFAP2A",
        "hgnc": "HGNC:11742",
        "name": "transcription factor AP-2 alpha",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tfap2a"
      }
    ]
  }
}