{
  "url": "https://dantelabs.com/traits/visual-fixation-instability",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "visual-fixation-instability",
    "id": "HP:0025405",
    "name": "Visual fixation instability",
    "definition": "A deficit in the ability to fixate eye movements in order to stabilize images on the retina",
    "synonyms": [
      "Instability of ocular fixation"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-eye",
        "name": "Abnormality of the eye",
        "url": "https://dantelabs.com/traits/abnormality-of-the-eye"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-visual-fixation",
        "name": "Abnormal visual fixation",
        "url": "https://dantelabs.com/traits/abnormal-visual-fixation"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "ankh",
        "symbol": "ANKH",
        "hgnc": "HGNC:15492",
        "name": "ANKH inorganic pyrophosphate transport regulator",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ankh"
      },
      {
        "slug": "ccdc88a",
        "symbol": "CCDC88A",
        "hgnc": "HGNC:25523",
        "name": "coiled-coil and HOOK domain protein 88A",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ccdc88a"
      },
      {
        "slug": "clcn3",
        "symbol": "CLCN3",
        "hgnc": "HGNC:2021",
        "name": "Cl-/H+ antiporter 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clcn3"
      },
      {
        "slug": "lim2",
        "symbol": "LIM2",
        "hgnc": "HGNC:6610",
        "name": "lens intrinsic membrane protein 2",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/lim2"
      },
      {
        "slug": "opa1",
        "symbol": "OPA1",
        "hgnc": "HGNC:8140",
        "name": "OPA1 mitochondrial dynamin like GTPase",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/opa1"
      },
      {
        "slug": "tefm",
        "symbol": "TEFM",
        "hgnc": "HGNC:26223",
        "name": "transcription elongation factor, mitochondrial",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/tefm"
      },
      {
        "slug": "ampd2",
        "symbol": "AMPD2",
        "hgnc": "HGNC:469",
        "name": "adenosine monophosphate deaminase 2",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/ampd2"
      },
      {
        "slug": "aspa",
        "symbol": "ASPA",
        "hgnc": "HGNC:756",
        "name": "aspartoacylase",
        "frequency": "very-frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/aspa"
      },
      {
        "slug": "rnf13",
        "symbol": "RNF13",
        "hgnc": "HGNC:10057",
        "name": "ring finger protein 13",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/rnf13"
      },
      {
        "slug": "slc39a8",
        "symbol": "SLC39A8",
        "hgnc": "HGNC:20862",
        "name": "solute carrier family 39 member 8",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/slc39a8"
      },
      {
        "slug": "vps4a",
        "symbol": "VPS4A",
        "hgnc": "HGNC:13488",
        "name": "vacuolar protein sorting 4 homolog A",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/vps4a"
      },
      {
        "slug": "asah1",
        "symbol": "ASAH1",
        "hgnc": "HGNC:735",
        "name": "N-acylsphingosine amidohydrolase 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/asah1"
      },
      {
        "slug": "clp1",
        "symbol": "CLP1",
        "hgnc": "HGNC:16999",
        "name": "cleavage factor polyribonucleotide kinase subunit 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/clp1"
      },
      {
        "slug": "itpr1",
        "symbol": "ITPR1",
        "hgnc": "HGNC:6180",
        "name": "inositol 1,4,5-trisphosphate receptor type 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/itpr1"
      },
      {
        "slug": "mab21l1",
        "symbol": "MAB21L1",
        "hgnc": "HGNC:6757",
        "name": "mab-21 like 1",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mab21l1"
      },
      {
        "slug": "pet100",
        "symbol": "PET100",
        "hgnc": "HGNC:40038",
        "name": "PET100 cytochrome c oxidase chaperone",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pet100"
      }
    ]
  }
}