{
  "url": "https://dantelabs.com/traits/prune-belly",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "prune-belly",
    "id": "HP:0004392",
    "name": "Prune belly",
    "definition": "A kind of congenital defect of the anterior abdominal wall in which the intestines are evident through the thin, lax, and protruding abdominal wall in affected infants.",
    "synonyms": [],
    "systems": [
      {
        "slug": "abnormality-of-the-digestive-system",
        "name": "Abnormality of the digestive system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-digestive-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-abdominal-wall-morphology",
        "name": "Abnormality of the abdominal wall",
        "url": "https://dantelabs.com/traits/abnormal-abdominal-wall-morphology"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "myh11",
        "symbol": "MYH11",
        "hgnc": "HGNC:7569",
        "name": "myosin heavy chain 11",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/myh11"
      },
      {
        "slug": "chrm3",
        "symbol": "CHRM3",
        "hgnc": "HGNC:1952",
        "name": "cholinergic receptor muscarinic 3",
        "frequency": "frequent",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/chrm3"
      },
      {
        "slug": "alkbh8",
        "symbol": "ALKBH8",
        "hgnc": "HGNC:25189",
        "name": "alkB homolog 8, tRNA methyltransferase",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/alkbh8"
      },
      {
        "slug": "piezo1",
        "symbol": "PIEZO1",
        "hgnc": "HGNC:28993",
        "name": "piezo type mechanosensitive ion channel component 1 (Er blood group)",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/piezo1"
      }
    ]
  }
}